Cell Death News and Research

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How does penicillin work?

In this interview, we spoke to Dr. Bartlomiej Salamaga about his latest research that discovered how penicillin works in the body.

24 Nov 2021

Study identifies key factor sustaining malignant tumor state

In a study published in Nature Cancer, researchers led by Prof. Cedric Blanpain, WELBIO investigator, Director of the Laboratory of Stem Cells and Cancer and Professor at the Université libre de Bruxelles, Belgium, demonstrated that NR2F2 is an essential regulator of malignant tumor state by controlling cancer stem cell and tumor maintenance in mouse and human cancers.

22 Nov 2021

Monitoring cellular metabolism for NAFLD/NASH liver disease research

In this interview, Jolanta Vidugiriene, a Senior Research Scientist at Promega Corporation, talks to News-Medical about tools for studying metabolism in NAFLD/NASH research.

From Promega Corporation 22 Nov 2021

Discovery of new receptor that interacts with SARS-CoV-2 spike, suppresses infection

Researchers recently conducted a study to identify host factors affecting cellular interactions of the SARS-CoV-2 spike protein.

16 Nov 2021

Deficient spike-specific T cell responses and inability to neutralize SARS-CoV-2 variants 12 month post-infection

Researchers conducted a comprehensive, longitudinal, long-term immune study, including functional assays to assess immune fitness against antigenically different VoC. The study is currently available on the preprint server medRxiv* while awaiting peer review.

15 Nov 2021

Study highlights the need for caution while using CRISPR-based gene therapies

A comprehensive study - conducted by researchers at Sanford Burnham Prebys, the National Cancer Institute (NCI) and other groups - has shown that gene editing, specifically gene knockout (KO), with CRISPR -Cas9 can favor cells with mutated forms of genes linked to cancer.

11 Nov 2021

New method of stem cell transplantation may eliminate the need for radiation or chemotherapy

Studying mice, researchers at Washington University School of Medicine in St. Louis have developed a method of stem cell transplantation that does not require radiation or chemotherapy.

10 Nov 2021

COVID-19 and loss of sense of smell

A recent review examines the high susceptibility of the olfactory epithelium to SARS-CoV-2 infection.

9 Nov 2021

SARS-CoV-2 infection regulates protein arginylation

A new study explores the role of arginylation during SARS-CoV-2 infection.

9 Nov 2021

Pacific oyster shows antiviral activity against human coronavirus HCoV-229E

Not only are Pacific oysters (Crassostrea gigas) a seafood delicacy, but they may also be key for helping scientists figure out how to stop the spread of coronaviruses.

7 Nov 2021

Therapeutics that target ceramides may help treat cardiometabolic disease

Therapeutics that target lipids called ceramides might hold potential for treating cardiometabolic disease, argues a review article published November 5th in the journal Trends in Pharmacological Sciences.

7 Nov 2021

Placental cell-type productively infected with SARS-CoV-2

A new preprint describes the development of a new platform for evaluating the risk of SARS-CoV-2 infection in placental tissue.

2 Nov 2021

Research reveals how gut macrophages respond to prior infection by shielding enteric neurons

A simple stomach bug could do a lot of damage. There are 100 million neurons scattered along the gastrointestinal tract - directly in the line of fire - that can be stamped out by gut infections, potentially leading to long-term GI disease.

30 Oct 2021

Cancer cells exploit genetic and cellular processes to promote tumor growth

Writing in EMBO reports, researchers at University of California San Diego School of Medicine and Moores Cancer Center at UC San Diego Health describe how a pair of fundamental genetic and cellular processes are exploited by cancer cells to promote tumor survival and growth.

29 Oct 2021

Scientists uncover key genetic networks governing human embryonic stem cell behavior

At the earliest stages of human embryonic development, a small collection of cells known as human embryonic stem cells (hESCs) orchestrates growth and differentiation, eventually giving rise to highly specialized human tissues.

28 Oct 2021

UAB researchers show how to identify non-responding tumors and improve immunotherapy response

Immunotherapy using checkpoint inhibitors can work well to treat cancer, but only a minority of patients respond to therapy.

28 Oct 2021

A new approach to selectively turn on gene therapies in target cells

Researchers at MIT and Harvard University have designed a way to selectively turn on gene therapies in target cells, including human cells.

28 Oct 2021

Study uncovers how novel coronavirus disrupts normal cell defenses to hijack human host cells

A UBC-led research team has uncovered how the virus responsible for causing COVID-19 escapes destruction in infected cells, allowing SARS-CoV-2 to persist and continue spreading in the human body.

27 Oct 2021

Nanoparticle-mediated, slow-release delivery of TT-10 enhances heart attack recovery in mouse model

A heart attack kills heart muscle cells, leading to a scar that weakens the heart, often leading to eventual heart failure. The lack of muscle repair is due to the very limited ability of mammalian heart muscle cells to proliferate, except for a brief period around birth.

25 Oct 2021

Researchers employ novel algorithm to identify candidate cancer drugs for pulmonary hypertension

By combining computational and experimental approaches, University of Pittsburgh School of Medicine and Prairie View A&M University researchers identified cancer drugs that show promise for treating pulmonary hypertension, or PH, a rare and incurable lung disease.

21 Oct 2021

Cell Death News and Research

How does penicillin work?

Study identifies key factor sustaining malignant tumor state

Monitoring cellular metabolism for NAFLD/NASH liver disease research

Discovery of new receptor that interacts with SARS-CoV-2 spike, suppresses infection

Deficient spike-specific T cell responses and inability to neutralize SARS-CoV-2 variants 12 month post-infection

Study highlights the need for caution while using CRISPR-based gene therapies

New method of stem cell transplantation may eliminate the need for radiation or chemotherapy

COVID-19 and loss of sense of smell

SARS-CoV-2 infection regulates protein arginylation

Pacific oyster shows antiviral activity against human coronavirus HCoV-229E

Therapeutics that target ceramides may help treat cardiometabolic disease

Placental cell-type productively infected with SARS-CoV-2

Research reveals how gut macrophages respond to prior infection by shielding enteric neurons

Cancer cells exploit genetic and cellular processes to promote tumor growth

Scientists uncover key genetic networks governing human embryonic stem cell behavior

UAB researchers show how to identify non-responding tumors and improve immunotherapy response

A new approach to selectively turn on gene therapies in target cells

Study uncovers how novel coronavirus disrupts normal cell defenses to hijack human host cells

Nanoparticle-mediated, slow-release delivery of TT-10 enhances heart attack recovery in mouse model

Researchers employ novel algorithm to identify candidate cancer drugs for pulmonary hypertension

Event Guide: 3rd Annual TRP Supply Chain & Manufacturing Summit eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics