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New insight into how genes and proteins go awry in autism to alter the mind

For decades, autism researchers have faced a baffling riddle: how to unravel a disorder that leaves no known physical trace as it develops in the brain.

26 May 2011

Sangamo announces presentations of ZFP Therapeutics data at ASGCT 2011

Sangamo BioSciences, Inc. announced today that data from clinical, preclinical and research-stage programs focused on the development of zinc finger DNA-binding protein Therapeutics were described in twenty presentations given by Sangamo scientists and collaborators at the 14th Annual Meeting of the American Society of Gene and Cell Therapy.

23 May 2011

Golden Helix integrates CMC and KBAC methods of analyzing rare DNA sequence variants in SVS product

Though two of the best-known methods for analyzing rare variants in sequencing data were published in 2008 and 2010, they have never been available to the public as a supported package.

21 May 2011

New research contributes to basic biological understanding of how retinas develop

New research at UC Santa Barbara is contributing to the basic biological understanding of how retinas develop. The study is part of the campus's expanding vision research.

21 May 2011

Researchers develop cheap, reliable diagnostic test for HLRCC

Researchers at the University of Oxford have developed a cheap and reliable diagnostic test for a rare form of cancer. The test involves screening tumour samples for a particular molecular fingerprint unique to this type of cancer.

21 May 2011

Two genes linked to worst cases of esophageal cancer

University of Rochester Medical Center researchers have pinpointed two genes that are amplified in the worst cases of esophageal cancer, providing data to support a new investigational treatment that targets those same genes.

19 May 2011

Children exposed to maternal smoking in utero have increased DNA methylation in AXL gene

Children whose mothers or grandmothers smoked during pregnancy are at increased risk of asthma in childhood, but the underlying causes of this are not well understood. Now a new study indicates changes in a process called DNA methylation that occurs before birth may be a root cause.

19 May 2011

Pacific Biosciences, Mount Sinai collaborate to advance genomic research

Mount Sinai School of Medicine and Pacific Biosciences of California, Inc. announced a bi-coastal collaboration to advance clinical research through the Mount Sinai Institute for Genomics and Multiscale Biology to be led by Eric E. Schadt, Ph.D.

16 May 2011

Researchers untangle two distinct ways in which tumor-suppressor protein works

Researchers at the Stanford University School of Medicine have untangled two distinct ways in which a common, naturally occurring "tumor-suppressor" protein works.

13 May 2011

UT Southwestern researcher measures estrogen's effect on breast cancer cells

A UT Southwestern Medical Center researcher has identified the most comprehensive measurement to date of estrogen's effect on breast cancer cells, showing for the first time how immediate and extensive the effect is.

6 May 2011

Eurotrans-Bio awards 1.1 million grant to MDxHealth, NovioGendix for bladder cancer program

MDxHealth SA, a leading molecular diagnostics company in the field of personalized cancer treatment, today announced that together with partner NovioGendix B.V., a molecular diagnostics company spun out from Radboud University Nijmegen Medical Centre, the Netherlands, has received a USD 1.1 million grant from Eurotrans-Bio to progress its bladder cancer program.

3 May 2011

SaneVax criticizes FDA for approval of Roche's cobas HPV genotyping test

In an April 22, 2011 letter to FDA Commissioner; Dr. Margaret Hamburg, Norma Erickson on behalf of the SaneVax Inc. Board of Directors, criticized the FDA for not following its own guidelines and recommendations in approving Roche's cobas HPV Test for cervical cancer screening and for HPV-16 and HPV-18 genotyping.

30 Apr 2011

Researchers unravel mechanism behind sickle hemoglobin protection against malaria

The latest issue of the journal Cell carries an article that is likely to help solve one of the long-standing mysteries of biomedicine. In a study that challenges currently held views, researchers at the Instituto Gulbenkian de Ci-ncia, in Portugal, unravel the molecular mechanism whereby sickle cell hemoglobin confers a survival advantage against malaria, the disease caused by Plasmodium infection.

29 Apr 2011

Scientists identify new risk gene variant for depression

Max Planck scientists uncover surprising genetic links. Scientists from the Max Planck Institute for Psychiatry in Munich have compared the genomes of a total of 4,088 patients and 11,001 healthy control subjects from all over the world and identified a new risk gene variant for depression.

28 Apr 2011

Oxford Nanopore raises $41 million via private placement of ordinary shares

Oxford Nanopore Technologies Ltd., the UK-based developers of nanopore technology for the direct, electronic analysis of single molecules, today announced that it has raised £25 million in new funding via a private placement of ordinary shares in the Company.

From Oxford Nanopore Technologies 26 Apr 2011

DNA rearrangements in roundworm chromosomes offer insight into genome duplications in developing tumors

A study of DNA rearrangements in roundworm chromosomes may offer new insight into large-scale genome duplications that occur in developing tumors.

22 Apr 2011

Penn researchers explore the role of telomere caps in human aging

Researchers at the University of Pennsylvania School of Medicine are delving into the details of the complex structure at the ends of chromosomes.

21 Apr 2011

Adamis acquires cancer vaccine technology from UCSD

Adamis Pharmaceuticals Corporation (OTCBB: ADMP) today announced the completion of the acquisition of a unique patented cancer vaccine technology from the Regents of the University of California.

20 Apr 2011

Mother's diet during pregnancy can influence child's risk of obesity

Scientists have discovered that a mother's nutrition during pregnancy can strongly influence her child's risk of obesity many years later.

19 Apr 2011

Research on rare cancers

A cancer diagnosis can be a life-changing event. Many questions arise, with one of the first being, "Where should I be treated?" Patients diagnosed with rare cancers may have difficulty finding a physician knowledgeable in treating their type of cancer.

11 Apr 2011