Immune System News and Research

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Single-cell transcriptomes of immune cells offer insight into juvenile idiopathic arthritis

Juvenile idiopathic arthritis (JIA), a type of arthritis commonly occurring in children, is a chronic, inflammatory condition that affects the joints, causing pain, swelling, stiffness, and limiting the range of motion.

2 Jul 2025

Could your pregnancy diet shape your child’s immune future?

Researchers found that a pro-inflammatory maternal diet during pregnancy was linked to a 16% increased risk of type 1 diabetes in offspring. This large Danish cohort study suggests that maternal dietary patterns may shape long-term autoimmune risk in children.

2 Jul 2025

Researchers uncover how RNA modifications evade immune detection

The innate immune system is the body's first line of defense against pathogens and foreign substances. An essential component of this system are pattern recognition receptors, which recognize non-self RNA - such as that from viruses and bacteria - and trigger an immune response.

1 Jul 2025

HIV treatment linked to risk of early knee osteoarthritis

Acquired immune deficiency syndrome, or AIDS, caused by the human immunodeficiency virus (HIV), weakens the body's immune system and can be life-threatening if left untreated.

1 Jul 2025

Engineered protein silences harmful T cells in autoimmune disease

An engineered protein turns off the kind of immune cells most likely to damage tissue as part of Type-1 diabetes, hepatitis, multiple sclerosis, shows a new study in mice.

1 Jul 2025

Inflammaging may be a lifestyle phenomenon rather than a universal aging trait

Inflammation, long considered a hallmark of aging, may not be a universal human experience, according to a new study from Columbia University Mailman School of Public Health.

1 Jul 2025

Novel method to improve the biocompatibility and chronic stability of neural electrode implants

An international research team, including scientists from the Institut de Neurociències at the Universitat Autònoma de Barcelona (UAB), has developed a new solution to reduce the immune response triggered by neural prosthetics used after limb amputations or severe nerve injuries.

30 Jun 2025

GATE complex discovery sheds light on CMV's evasion of immune defenses

New research from the University of Pittsburgh School of Medicine and La Jolla Institute for Immunology, published today in Nature Microbiology, reveals an opportunity for developing a therapy against cytomegalovirus (CMV), the leading infectious cause of birth defects in the United States.

30 Jun 2025

Ancient DNA sheds light on the origins of leprosy in the Americas

Hansen's Disease, more commonly known as leprosy, is a chronic disease that can lead to physical impairment. Today it exists in over 100 countries, and while the infection is treatable, access to treatment varies widely with socioeconomic conditions.

30 Jun 2025

Study provides insights into the immune response following pig-to-human kidney xenotransplants

A pioneering study has provided unprecedented insights into the immune response following pig-to-human kidney xenotransplantation.

30 Jun 2025

Newly discovered target may re-energize exhausted immune cells in the fight against cancer

Van Andel Institute scientists and collaborators have discovered a potential treatment target that may re-energize dysfunctional or "exhausted" immune cells in their fight against cancer.

27 Jun 2025

Beetle-inspired tuberculosis testing device offers accurate detection for people with HIV

Current tuberculosis infection tests struggle to detect the disease in those with HIV. A common co-infection, HIV can hide TB from traditional tests by eliminating the immune cells relied upon to sound the alarm.

27 Jun 2025

Global effort enters an active growth phase to preserve the Earth's microbial heritage

A global effort to create a "microbial Noah's Ark" to preserve the world's diverse collection of healthy microbes before they disappear is now entering an active growth phase.

27 Jun 2025

New enzyme can be "turned off" to restore cholesterol balance and reduce inflammation

Scientists at The University of Texas at Arlington have identified a new enzyme that can be "turned off" to help the body maintain healthy cholesterol levels-a significant development that could lead to new treatments for diseases that affect millions of Americans.

27 Jun 2025

Pesticides found to disrupt specific gut bacteria linked to inflammation

While emerging evidence suggests pesticides can be toxic to the mix of microorganisms in the digestive system, a new study is the first to map changes to specific gut bacteria based on interactions between human microbes and insect-killing chemicals observed in the lab and an animal model.

27 Jun 2025

Partial match stem cell transplants show strong survival rates

Blood cancer patients who may have previously struggled to find a donor for transplantation now have more options.

26 Jun 2025

Fire smoke exposure found to alter immune system at the cellular level

Exposure to fire smoke-which can be composed of particulate matter, gases, materials from buildings such as perfluoroalkyl and polyfluoroalkyl substances (PFAS), toxic metals, and carcinogenic compounds-may alter the immune system on a cellular level, according to a new study led by researchers at Harvard T.H. Chan School of Public Health.

26 Jun 2025