Lipoprotein News and Research

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A lipoprotein is a biochemical assembly that contains both proteins and lipids. The lipids or their derivatives may be covalently or non-covalently bound to the proteins.

GW researcher to help HIV patients better understand treatments for cardiovascular issues

In 1980, men and women who were diagnosed with the human immunodeficiency virus (HIV) had little to no hope of living long, full lives. Thanks to advances in science and medicine, this is no longer the case. HIV patients now live a near-normal lifespan. However, as patients live longer, new medical issues arise.

3 Oct 2012

Eating apples might help keep the cardiologist away

Eating an apple a day might in fact help keep the cardiologist away, new research suggests.

3 Oct 2012

HDL may protect against abdominal aortic aneurysm

High levels of high-density lipoprotein cholesterol inhibit the formation of abdominal aortic aneurysm, findings from experimental mouse models suggest.

2 Oct 2012

Oil blend plus antihypertensive lowers blood pressure, cholesterol level

A blend of sesame and rice bran oil could reduce blood pressure by almost as much as an antihypertensive medication, say researchers.

1 Oct 2012

Cholesterol has repercussions for recovering heroin addicts

Cholesterol levels may be negatively associated with heroin craving in patients on methadone maintenance therapy, researchers suggest.

1 Oct 2012

ApoA-V as a contributor to dyslipidemia in obese children

Insulin may be an important regulator of serum apolipoprotein A-V levels in obese people and may contribute to the development of obesity-associated dyslipidemia, say Japanese researchers.

27 Sep 2012

Enrollment complete in Resverlogix‘s RVX-208 Phase 2b trial on cardiovascular disease

Resverlogix Corp. today announced that it has completed enrollment in ASSURE, a Phase 2b clinical trial targeting high-risk cardiovascular disease patients.

27 Sep 2012

High uric acid precursor of obesity, metabolic syndrome

The relationship between uric acid and early cardiometabolic risk may precede obesity and the metabolic syndrome, show study findings.

20 Sep 2012

Pfizer announces that 14 abstracts for tofacitinib to be presented at ACR/ARHP annual meeting

Pfizer Inc. announced today that 14 abstracts for tofacitinib, an investigational oral Janus kinase (JAK) inhibitor for the treatment of adults with moderate-to-severe active rheumatoid arthritis (RA), will be presented at the American College of Rheumatology (ACR) / Association of Rheumatology Health Professionals (ARHP) 2012 Annual Meeting, which is being held November 9-14 in Washington, D.C.

18 Sep 2012

Type 2 diabetes mellitus patients are at increased risk for cardiovascular disease

LipoScience, Inc., a highly innovative diagnostic company that is advancing patient care by developing high value proprietary blood tests using nuclear magnetic resonance technology, today announced the publication of results from a clinical study in the American Journal of Cardiology suggesting that despite having cholesterol levels considered acceptable by today's clinical standards, patients with Type 2 diabetes mellitus (T2DM) are at increased risk for cardiovascular disease-related events.

17 Sep 2012

Pam2Cys nasal spray may be useful agent against pandemics and emerging viral strains

In an advance toward development of a nasal spray that protects against infection with influenza and spread of the disease, scientists are reporting identification of a substance that activates the first-line defense system against infection inside the nose. They describe effects of a synthetic form of a natural substance found in bacterial cell walls in ACS' journal Molecular Pharmaceutics.

13 Sep 2012

Angiopoietin-like protein 2 level linked to incident diabetes

Elevated angiopoietin-like protein 2 levels are associated with the development of Type 2 diabetes, show findings from a Japanese study.

12 Sep 2012

ApoB no better than current lipid markers in CVD risk prediction

Assessment of apolipoprotein B levels does not seem to improve cardiovascular disease risk prediction over low-density lipoprotein cholesterol and non-high-density lipoprotein cholesterol, report researchers.

11 Sep 2012

Endocrine Society issues practice guideline for diagnosis and treatment of hypertriglyceridemia

The Endocrine Society today issued a Clinical Practice Guideline (CPG) for the diagnosis and treatment of hypertriglyceridemia. Triglycerides are a type of fat found in the blood and are associated with cardiovascular risk. The CPG, entitled "Evaluation and Treatment of Hypertriglyceridemia: An Endocrine Society Clinical Practice Guideline" appears in the September 2012 issue of the Journal of Clinical Endocrinology and Metabolism (JCEM), a publication of The Endocrine Society.

10 Sep 2012

Vitamin D supplements have unintended lipid consequences

Correcting vitamin D levels in individuals at risk for cardiovascular disease may have detrimental effects on their lipid profiles, report researchers.

6 Sep 2012

Study questions use of vitamin D supplements to improve cholesterol

Vitamin D has been touted for its beneficial effects on a range of human systems, from enhancing bone health to reducing the risk of developing certain cancers. But it does not improve cholesterol levels, according to a new study conducted at The Rockefeller University Hospital.

From Quest Diagnostics 5 Sep 2012

Update on Merck's development programs for vorapaxar, ER niacin/laropirprant and anacetrapib

Merck today provided an update on the development programs for vorapaxar, extended release niacin/laropirprant (MK524A, Tredaptive) and anacetrapib in association with the European Society of Cardiology (ESC) meeting in Munich.

27 Aug 2012

HDL cholesterol benefits reduced with high C-reactive protein

The cardioprotective effects of high-density lipoprotein cholesterol are compromised in the presence of elevated high-sensitivity C-reactive protein, report researchers.

21 Aug 2012

Total cholesterol test can identify patients at increased risk of heart disease

Researchers in India have developed a total cholesterol test that uses a digital camera to take a snapshot of the back of the patient's hand rather than a blood sample. The image obtained is cropped and compared with images in a database for known cholesterol levels.

18 Aug 2012

Tofacitinib shows promise in active ulcerative colitis

Tofacitinib can induce a clinical response in the majority of patients with moderate to severe, active ulcerative colitis, a placebo-controlled trial has shown.

16 Aug 2012