Lymph Nodes News and Research

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Research finding could lead to potential treatment for lymphedema

The molecule interleukin-7 is an important immune messenger protein which ensures that a sufficient number of T cells are present in our body for immune defence. Researchers from ETH Zurich have now demonstrated that IL-7 has another important function: it enhances the drainage function of lymphatic vessels, which collect fluid that has leaked out of blood vessels into the body tissue and return it to the bloodstream.

27 Aug 2013

Northwestern surgical oncologists use minimally invasive procedure to remove malignant melanoma

That's when she received the results from her dermatologist, who removed a part of the blister and had it tested. It turns out that little red bump was malignant melanoma, the leading cause of skin cancer death in the United States. It's a cancer that kills one person every hour, which translates to more than 8,700 Americans each year.

27 Aug 2013

Even in advanced stages total tumor size can have major impact on survival in lung cancer patients

For the two-thirds of lung cancer patients with locally advanced or metastatic disease, tumor size is not used currently to predict overall survival times. A new study, however, led by UT Southwestern Medical Center researchers has shown that even in advanced stages total tumor size can have a major impact on survival.

20 Aug 2013

Study shows lymph node location influences maturation process of cells they contain

Based on their observations, the scientists deduced that lymph node location influences the maturation process of the cells they contain. "The cells retained their original skills for weeks following the transplant," says Dr. Sascha Cording, one of the study's first authors. "You might say lymph nodes have something like a location-specific memory."

17 Aug 2013

Chemo before radiotherapy improves efficacy of treatment in testicular cancer patients with low side effects

Giving men with testicular cancer a single dose of chemotherapy alongside radiotherapy could improve the effectiveness of treatment and reduce the risk of long-term side-effects, a new study reports.

17 Aug 2013

Breast cancer survivors are more likely to develop debilitating disorder arm lymphoedema

Breast cancer survivors who have extensive surgery are four times more likely to develop the debilitating disorder arm lymphoedema, a QUT study has found.

8 Aug 2013

Celiac disease patients with persistent intestine damage are at higher risk of lymphoma

Patients with celiac disease who had persistent intestine damage (identified with repeat biopsy) had a higher risk of lymphoma than patients whose intestines healed, according to findings published in the August 6, 2013, issue of Annals of Internal Medicine.

6 Aug 2013

Research: Lymph nodes provide correct breast cancer prognosis

After a breast cancer operation, the removed tumour is always examined, as its subtype can provide an indication of how aggressive the disease is. The patient's lymph nodes are not analysed in the same way.

29 Jul 2013

Innovative microsurgery technique helps prevent lymphedema in patients with breast cancer

A team of surgeons and members of the breast cancer program of the Herbert Irving Comprehensive Cancer Center at NewYork-Presbyterian Hospital/Columbia University Medical Center is conducting a two-year pilot study of an innovative microsurgery technique coupled with imaging technology to not only prevent lymphedema but also potentially detect and treat it early.

24 Jul 2013

Robotic retroperitoneal lymph node dissection (RPLND) for testicular cancer: an interview with Dr. Stephen Williams of St. Joseph Hospital in Orange

Robotic RPLND utilizes laparoscopy combined with robotic technology to perform dissection and removal of lymph node tissue in the retroperitoneum both as a staging as well as therapeutic procedure for patients with testicular cancer.

10 Jul 2013

Innovative vaccine could offer hope to patients with advanced ovarian cancer

Loyola University Medical Center is conducting a clinical trial of an innovative vaccine that could offer hope to patients with advanced ovarian cancer.

10 Jul 2013

Genentech's Perjeta regimen gets FDA Priority Review for HER2-positive early stage breast cancer

Genentech, a member of the Roche Group, today announced that the U.S. Food and Drug Administration has accepted the company's supplemental Biologics License Application for the use of a Perjeta (pertuzumab) regimen before surgery (neoadjuvant treatment) in people with HER2-positive early stage breast cancer.

2 Jul 2013

Tiny RNA molecules work as powerful regulators of immune response in mammals

A team led by scientists at The Scripps Research Institute (TSRI) has identified a family of tiny RNA molecules that work as powerful regulators of the immune response in mammals. Mice who lack these RNA molecules lose their normal infection-fighting ability, whereas mice that overproduce them develop a fatal autoimmune syndrome.

1 Jul 2013

Patients' medical follow-up after melanoma diagnosis should be lifelong, says study author

Recurrence of melanoma skin cancer 10 or more years after initial treatment is more common than previously thought, occurring in more than one in 20 patients. However, according to a new study, these patients tend to live longer after their cancer returns than patients whose melanoma recurs in the first three years.

28 Jun 2013

Pretreatment PET staging of LS-SCLC associated with improved survival

Each year, 13 percent of all newly diagnosed lung cancer patients are diagnosed with small-cell lung cancer (SCLC). Approximately 39 percent of patients with SCLC are diagnosed with limited-stage disease, meaning the cancer is only present in one lung, but may have spread to lymph nodes or tissue between the lungs.

26 Jun 2013

Sentinel lymph node biopsy for early breast cancer: an interview with Prof. Gordon Wishart, Anglia Ruskin University

Our current method, which is recommended by the Association of Breast Surgeons in the UK, involves the use of injections of blue dye and radioisotope to identify the first node(s) under the arm (axilla) called the sentinel nodes.

25 Jun 2013

Endosonographic aspiration procedures result in greater diagnostic yield in treating pulmonary sarcoidosis

Among patients with suspected stage I/II pulmonary sarcoidosis who were undergoing confirmation of the condition via tissue sampling, the use of the procedure known as endosonographic nodal aspiration compared with bronchoscopic biopsy, the current diagnostic standard, resulted in greater diagnostic yield, according to a study in the June 19 issue of JAMA.

19 Jun 2013

Study demonstrates efficacy of canakinumab at tapering corticosteroid use in patients with SJIA

Study findings first presented today at EULAR 2013, the Annual Congress of the European League Against Rheumatism, demonstrate the efficacy of canakinumab at tapering corticosteroid (CS) use in patients with SJIA.

14 Jun 2013

New imaging system combines PET and MR for mapping recurrent prostate cancer

When prostate cancer makes a comeback, it becomes increasingly important to have exceptional imaging available to find all possible regions where cancer has spread to other parts of the body, or metastasized, in order to plan the best possible treatment.

12 Jun 2013

PSMA enzyme could become hallmark of new generation of biomarkers for prostate cancer treatment

No matter where they have hidden, metastatic prostate cancer cells still express some of the same signaling as normal prostate cells; in some cases even more so, as with the PSMA enzyme. Harnessing this enzyme could mean the beginning of a new platform for prostate cancer detection, staging, treatment and post-treatment monitoring, say researchers at the Society of Nuclear Medicine and Molecular Imaging's 2013 Annual Meeting.