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Oligodendrocytes may have a different role in the development of multiple sclerosis, study finds

An international team of researchers led by Karolinska Institutet in Sweden have discovered that a cell type in the central nervous system known as oligodendrocytes might have a different role in the development of multiple sclerosis (MS) than previously thought.

28 Jan 2022

Blood tests may enable simpler, more accurate early diagnosis of ALS

Blood tests may enable more accurate diagnosis of ALS at an earlier stage of the disease. As described in a study by researchers at University of Gothenburg and Umeå University, it involves measuring the blood level of a substance that, as they have also shown, varies in concentration depending on which variant of ALS the patient has.

28 Jan 2022

Desipramine and L-cycloserine together reduce ceramide levels in the retina and enhance vision

Researchers from the University of California, Irvine have discovered that the absence of Adiponectin receptor 1 protein (AdipoR1), one of the principal enzymes regulating ceramide homeostasis in the retina, leads to an accumulation of ceramides in the retina, resulting in progressive photoreceptor cell death and ultimately vision loss.

28 Jan 2022

Research teases out connection between diet, immune response, gut bacteria and multiple sclerosis

Eating more meat, having less of certain bacteria in the gut, and more of certain immune cells in the blood, all link with multiple sclerosis, reports a team of researchers led by UConn Health and Washington University School of Medicine.

27 Jan 2022

ANU researchers identify why Th17 cells go rogue and promote the onset of multiple sclerosis

Researchers from The Australian National University (ANU) have identified why certain cells in the body, known as Th17 cells, go rogue and promote the onset of autoimmune diseases such as multiple sclerosis (MS).

27 Jan 2022

Novel experimental drug designed to silence FUS gene may help treat ALS

Using an experimental drug, researchers were able to suppress a mutated amyotrophic lateral sclerosis (ALS) gene.

24 Jan 2022

Eikonoklastes completes a license to add novel gene therapy for treating neurodegenerative diseases

Eikonoklastes Therapeutics, a preclinical stage biopharmaceutical company, today announced it has completed a license with the University of California San Diego to add a novel gene therapy for the treatment of neurodegenerative diseases.

20 Jan 2022

Novel robotic replica of human spine enables surgeons to preview the effects of surgery

Degenerative disc disease affects about 40 percent of people aged 40, increasing to about 80 percent among those aged 80 or older. The disease, which is the deterioration of one or more intervertebral discs of the spine, often is surgically treated with cervical disc implants.

19 Jan 2022

Scientists reveal toxic astrocyte changes in ALS

Scientists at the Francis Crick Institute have revealed harmful changes in supporting cells, called astrocytes, in Amyotrophic Lateral Sclerosis (ALS) in two publications in Brain and Genome Research.

19 Jan 2022

Machine learning model identifies new risk genes for motor neurone disease

Scientists have developed a new machine learning model for the discovery of genetic risk factors for diseases such as Motor Neurone Disease (MND).

18 Jan 2022

New MRI technique could pave the way to quicker assessment of multiple sclerosis

It is important that multiple sclerosis (MS) is diagnosed and treated as early as possible in order to delay progression of the disease.

18 Jan 2022

Multiple sclerosis may be caused by infection with the Epstein-Barr virus

Multiple sclerosis (MS), a progressive disease that affects 2.8 million people worldwide and for which there is no definitive cure, is likely caused by infection with the Epstein-Barr virus (EBV), according to a study led by Harvard T.H. Chan School of Public Health researchers.

13 Jan 2022

Novel biomarker can be used to identify disease progression in ALS

An international collaboration led by Flinders University has identified a potential biomarker for amyotrophic lateral sclerosis, also known as Motor Neuron Disease, providing a way to test the effectiveness of future clinical trials.

13 Jan 2022

Study finds evidence for increased activity of the brain’s immune system long before dementia onset

Long before the onset of dementia, there is evidence for increased activity of the brain's immune system. Researchers from DZNE and the University Hospital Bonn come to this conclusion based on a study of more than 1,000 older adults.

12 Jan 2022

Cellular and humoral response to SARS-CoV-2 in multiple sclerosis patients using disease-modifying therapies

Researchers examine the effects of disease-modifying therapies implemented for treating multiple sclerosis on the immune response to SARS-CoV-2 infection.

12 Jan 2022

New type of blood test can be used to detect cancers as well as metastatic disease

A publication by University of Oxford researchers describes a new minimally invasive and inexpensive blood test that can identify cancer in patients with non-specific symptoms.

12 Jan 2022

Decoding imagined language to treat people suffering from aphasia

What if it were possible to decode the internal language of individuals deprived of the ability to express themselves? This is the objective of a team of neuroscientists from the University of Geneva (UNIGE) and the University Hospitals of Geneva.

11 Jan 2022

Biosimilars could drive down drug prices and lead to $38.4 billion savings

Biosimilar drugs could drive down prices for expensive medicines used to treat illnesses such as cancer and rheumatoid arthritis, with savings estimated to be $38.4 billion or 5.9% of projected total U.S. spending on biologics from 2021 to 2025, according to a new RAND Corporation study.

10 Jan 2022

Slight pH adjustment may turn a metabolic inhibiting drug into promising COVID-19 treatment

Mechanical engineering and materials science professor David Needham has shown that a slight increase in solution pH might be all it takes to turn a metabolic inhibiting drug, traditionally used to treat gut parasites, into a promising prophylactic/preventative nasal spray and early treatment throat spray for COVID-19.

7 Jan 2022

Moderna announces initiation of Phase 1 study of its mRNA-1189 EBV vaccine candidate

Moderna, Inc., a biotechnology company pioneering messenger RNA therapeutics and vaccines, today announced the first participant has been dosed in the Phase 1 study of mRNA-1189, the Company's Epstein-Barr Virus vaccine candidate.

7 Jan 2022

Sclerosis News and Research

Oligodendrocytes may have a different role in the development of multiple sclerosis, study finds

Blood tests may enable simpler, more accurate early diagnosis of ALS

Desipramine and L-cycloserine together reduce ceramide levels in the retina and enhance vision

Research teases out connection between diet, immune response, gut bacteria and multiple sclerosis

ANU researchers identify why Th17 cells go rogue and promote the onset of multiple sclerosis

Novel experimental drug designed to silence FUS gene may help treat ALS

Eikonoklastes completes a license to add novel gene therapy for treating neurodegenerative diseases

Novel robotic replica of human spine enables surgeons to preview the effects of surgery

Scientists reveal toxic astrocyte changes in ALS

Machine learning model identifies new risk genes for motor neurone disease

New MRI technique could pave the way to quicker assessment of multiple sclerosis

Multiple sclerosis may be caused by infection with the Epstein-Barr virus

Novel biomarker can be used to identify disease progression in ALS

Study finds evidence for increased activity of the brain’s immune system long before dementia onset

Cellular and humoral response to SARS-CoV-2 in multiple sclerosis patients using disease-modifying therapies

New type of blood test can be used to detect cancers as well as metastatic disease

Decoding imagined language to treat people suffering from aphasia

Biosimilars could drive down drug prices and lead to $38.4 billion savings

Slight pH adjustment may turn a metabolic inhibiting drug into promising COVID-19 treatment

Moderna announces initiation of Phase 1 study of its mRNA-1189 EBV vaccine candidate

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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