Drugs News and Research

RSS

Novel nanospectroscopy measures biomolecular changes induced by drugs in human cells

Synchrotron InfraRed Nanospectroscopy has been used for the first time to measure biomolecular changes induced by a drug (amiodarone) within human cells (macrophages) and localized at 100 nanometre scale, i.e. two orders of magnitude smaller than the IR wavelength used as probe.

17 Jul 2020

Study reveals antiviral effects of curcumin

Curcumin, a natural compound found in the spice turmeric, could help eliminate certain viruses, research has found.

17 Jul 2020

Study could help develop new drugs for toxoplasma infection

Researchers at Indiana University School of Medicine have discovered new information about how a dangerous parasite takes control of a patient's cells as it spreads throughout their body, an important finding that could help in the development of new drugs to treat this infection.

17 Jul 2020

Common antioxidant enzyme catalase as COVID-19 treatment

A new paper by researchers from the USA and China and published on the preprint server bioRxiv in July 2020 discusses a new drug based on the catalase enzyme, which could play a vital part in reducing the inflammation associated with progressive and severe COVID-19 disease.

17 Jul 2020

Novel method for selecting the best drug therapy for cancer

Choosing the right drug for each cancer patient is key to successful treatment, but physicians currently have few reliable pointers to guide them in designing treatment protocols.

17 Jul 2020

Rapid genomic surveillance of healthcare-associated SARS-CoV-2

The researchers from the University of Cambridge, Cambridge United Kingdom have published their findings in a study titled, “Rapid implementation of SARS-CoV-2 sequencing to investigate cases of healthcare-associated COVID-19: a prospective genomic surveillance study,” in the latest issue of The Lancet Infectious Diseases.

16 Jul 2020

Emerging hydrogel material could improve oral drug delivery

An emerging hydrogel material with the capacity to degrade and spontaneously reform in the gastrointestinal tract could help researchers develop more effective methods for oral drug delivery.

16 Jul 2020

New insight into the SARS-CoV-2 infection process

Canadian researchers from the Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, QC, have found that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may be using a unique method to gain entry into the cells.

16 Jul 2020

Advances in Alzheimer's drug development offer hope for patients

Dr. Jeffrey L. Cummings, UNLV research professor and a leading expert on Alzheimer's disease clinical trials, led a five-year review of all Alzheimer's drugs in the development pipeline. He says today there is more hope than ever that we'll one day solve Alzheimer's.

16 Jul 2020

Compelling study shows heparin may protect against COVID-19

A compelling new study conducted by an international team of researchers has demonstrated that the widely used blood-thinning medication - heparin - can block infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the agent that causes coronavirus disease 2019 (COVID-19).

16 Jul 2020

American beautyberry leaf extract boosts antibiotic's activity against 'superbug'

Scientists discovered a compound in the leaves of a common shrub, the American beautyberry, that boosts an antibiotic's activity against antibiotic-resistant staph bacteria.

16 Jul 2020

Yale researchers uncover potential treatment for lethal Wolfram Syndrome

Yale pharmacology professor Barbara Ehrlich and her team have uncovered a mechanism driving a rare, lethal disease called Wolfram Syndrome and also a potential treatment. Their findings appear in the July 6 edition of Proceedings of the National Academy of Sciences.

16 Jul 2020

Inflammageing may be related to worse COVID-19 outcomes in older individuals

The increased severity and mortality of SARS-CoV-2 infections in older individuals may be related to inflammageing - an age-associated phenomenon of increased general inflammation.

16 Jul 2020

UTHSC researchers receive $2.4 million to study the role of cholesterol in brain artery health

Alex Dopico, MD, PhD, professor and Van Vleet Chair of Excellence in the Department of Pharmacology, Addiction Science, and Toxicology, and Anna Bukiya, PhD, associate professor in the Department of Pharmacology, Addiction Science, and Toxicology, have been awarded $2.4 million from the National Heart, Lung, and Blood Institute to explore how cholesterol interacts with the mechanisms that modulate blood vessel function in the brain.

16 Jul 2020

Study could accelerate drug development to reduce age-related diseases

Genes linked to ageing that could help explain why some people age at different rates to others have been identified by scientists.

16 Jul 2020

Prominent pharmacologist calls for new approach to treat COVID-19

A prominent Australian pharmacologist has called for a new approach to treating COVID-19 as hopes fade of finding an effective vaccine or antiviral before the end of the year.

16 Jul 2020

Selective statins may reduce SARS-CoV-2 cell entry and inhibit infection

Statins are a class of drugs often used to control high cholesterol levels in obesity. Now, a study published on the preprint server medRxiv* in July 2020 suggests that statins do not aggravate the risk of COVID-19 infection and may have a small beneficial effect in some cases.

16 Jul 2020

Lung cancer study highlights important factors for treating genomically complicated cancers

A pioneering lung cancer study, led by the University of Birmingham's Cancer Research UK Clinical Trials Unit, has highlighted important factors that will need to be considered in the next wave of precision medicine studies particularly in treating genomically complicated cancers.

16 Jul 2020

Peptide-derived nanoparticle drug shows promise for treating heart attack

Researchers at the University of Illinois at Chicago have developed a new drug that prevents blood clots without causing an increased risk of bleeding, a common side effect of all antiplatelet medications currently available.

15 Jul 2020

Dopamine therapy improves cognitive function in patients with mild-to-moderate Alzheimer's

A study supported by the Alzheimer's Drug Discovery Foundation and published today in JAMA Network Open provides the first evidence that rotigotine, a drug that acts on dopamine transmission in the brain, improves cognitive function in patients with mild-to-moderate Alzheimer's disease.

15 Jul 2020