Liver News and Research

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Carnitine supplementation appears to prevent development of liver cancer

A study will be published on March 21, 2009 in World Journal of Gastroenterology addresses the question.

24 Mar 2009

Gilead commences phase II trial of Cicletanine for pulmonary arterial hypertension

Gilead Sciences, Inc. has announced that it has begun enrolling patients in a Phase II clinical trial of cicletanine hydrochloride (cicletanine), an oral agent in development for the treatment of pulmonary arterial hypertension (PAH).

24 Mar 2009

Canadian researchers to launch clinical trial to determine efficacy of treating latent TB with four-month course of Rifampin

Researchers at McGill University in Montreal on Tuesday announced they will soon launch an international clinical trial to determine if latent tuberculosis can be treated successfully with a four-month treatment course of the TB drug rifampin rather than the standard nine-month treatment with the TB drug isoniazid, the CP/Toronto Sun reports.

24 Mar 2009

Jaundice an unreliable method of predicting the baby's risk of hyperbilirubinemia

For hundreds of years, doctors, nurses and midwives have visually examined newborn babies for the yellowish skin tones that signify jaundice, judging that more extensive jaundice carried a greater risk of illness.

23 Mar 2009

Long-term daily drinking is biggest risk factor in serious liver disease

Long-term daily drinking, rather than weekly binge drinking, is by far the biggest risk factor in serious liver disease, according to a new report from the University of Southampton.

22 Mar 2009

FDA warning on oysters recently harvested from Mississippi area 2C

The U.S. Food and Drug Administration is advising retailers and food service operators not to offer for sale oysters harvested between Feb. 24 and March 17, 2009, from Mississippi Area 2C, located in the Mississippi Sound portion of the Gulf of Mexico near Pass Christian, Miss. Further, consumers are advised not to eat such oysters.

22 Mar 2009

Cathepsin B increases apoptosis in fulminant hepatic failure

The traditional view is that hepatocyte necrosis is the main feature of fulminant hepatic failure, but increasing evidence implicates a dominant role for hepatocyte apoptosis in this pathogenesis.

22 Mar 2009

Metabolism and aging linked to circadian rhythm

All animals, including humans, have an internal 24-hour clock or circadian rhythm that creates a daily oscillation of body temperature, brain activity, hormone production and metabolism.

20 Mar 2009

Researchers investigate new way to block reproduction of the hepatitis C virus

Massachusetts General Hospital (MGH) researchers are investigating a new way to block reproduction of the hepatitis C virus (HCV) - targeting not the virus itself but the human genes the virus exploits in its life cycle.

20 Mar 2009

Scots and Irish at greater risk of drink-related death, study shows

Alcohol-related deaths in England and Wales are twice as high among people born in Scotland or Ireland compared with the rest of the population, a study has shown.

20 Mar 2009

Biopsy of recurrent breast cancer can alter treatment

For women with recurrent breast cancer, the treatment the doctor chooses is usually based on the properties of their original breast cancer.

20 Mar 2009

Potential colon cancer being tested

Researchers at the University of Pittsburgh School of Medicine have begun testing a vaccine that might be able to prevent colon cancer in people at high risk for developing the disease.

20 Mar 2009

Naltrexone can reduce relapse rates among alcohol-dependence patients

Naltrexone, an opioid antagonist approved in 1994 by the U.S. Food and Drug Administration for alcohol-dependence (AD) treatment, can reduce relapse rates among AD patients.

20 Mar 2009

Discovery of gene that plays key role in process of converting dietary carbohydrates to fat

In a new study, they disabled this gene in mice, which consequently had lower levels of body fat than their normal counterparts, despite being fed the equivalent of an 'all-you-can-eat' pasta buffet.

20 Mar 2009

Gleevec reduces risk of cancer returning in patients with life-threatening gastrointestinal stromal tumors

Data published online and in an upcoming print issue of The Lancet show that Gleevec (imatinib mesylate) tablets, when taken after surgery, substantially reduces the rate of recurrence of Kit-positive gastrointestinal stromal tumors (GIST) compared with placebo.

20 Mar 2009