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Investigational antidepressant PT150 shows antiviral activity against SARS-CoV-2

In a recent bioRxiv study, an ad hoc multi-institutional research team from the US shows that a novel hormone receptor modulator PT150 has unique and possibly additive antiviral and immunomodulatory effects – highlighting its potential role in the treatment and prophylaxis of coronavirus disease (COVID-19).

14 Jul 2020

Researchers characterize how changes in glioblastoma cells influence different drug effects

Therapies for treating glioblastoma brain cancer can be delivered with greater precision and existing drugs can be used in new ways.

14 Jul 2020

Dual inhibitor therapy may be safer for CLL patients, Moffitt study shows

Chronic lymphocytic leukemia (CLL) is the most common leukemia in adults. One in four new leukemia cases are CLL.

14 Jul 2020

Absolute Antibody and University of Zurich partner to offer novel SARS-CoV-2 sybodies

Absolute Antibody Ltd., an industry-leading provider of recombinant antibody products and services, today announced a partnership with University of Zurich to offer synthetic nanobodies against the receptor binding domain (RBD) of SARS-CoV-2, the coronavirus that causes COVID-19.

From Absolute Antibody Ltd 14 Jul 2020

Researcher and health research journalist point out biased misinformation on coronavirus

In a new JAMA editorial, a Boston University School of Public Health (BUSPH) researcher and a health research journalist outline common ways that media, governments, and industry and academic public relations press releases have incompletely and misleadingly reported coronavirus research, and how they can do better.

14 Jul 2020

Researchers review scientific articles on the role of zinc in COVID-19 prevention

Researchers from Sechenov University in collaboration with colleagues from Germany, Greece and Russia reviewed scientific articles on the role of zinc in the prevention and treatment of viral infections and pneumonia, with projections on those caused by SARS-CoV-2. The results were published in the International Journal of Molecular Medicine.

14 Jul 2020

Compound in pickled capers can directly regulate proteins required for bodily processes

A compound commonly found in pickled capers has been shown to activate proteins required for normal human brain and heart activity, and may even lead to future therapies for the treatment of epilepsy and abnormal heart rhythms.

14 Jul 2020

Researchers uncover new mechanism for designing antiviral drugs for dengue virus

A multidisciplinary team from The University of Texas Medical Branch at Galveston has uncovered a new mechanism for designing antiviral drugs for dengue virus. The study is currently available in Proceedings of the National Academy of Sciences.

14 Jul 2020

People with accelerated biological age at increased risk of COVID-19 symptom severity and mortality

Now, a new study published on the preprint server medRxiv in July 2020 discusses the explanation in terms of the biological aging markers in patients with severe disease, rather than the chronological age.

13 Jul 2020

New substance library established to accelerate the systematic development of drugs

In order to accelerate the systematic development of drugs, the MX team at the Helmholtz-Zentrum Berlin (HZB) and the Drug Design Group at the University of Marburg have established a new substance library.

13 Jul 2020

COVID-19 – researchers sum up the “Tsunami” of information

The severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) infection leading to COVID-19 is a raging pandemic across the world at present. It has infected 13 million and killed 571,000 individuals around the world as of today. The infection was first reported in Wuhan, Hubei Province of China in late December 2019.

13 Jul 2020

Scientists discover common molecular feature found in SARS-CoV-2 neutralizing antibodies

A team led by scientists at Scripps Research has discovered a common molecular feature found in many of the human antibodies that neutralize SARS-CoV-2, the coronavirus that causes COVID-19.

13 Jul 2020

Study identifies three novel broad-spectrum SARS-CoV-2 cell entry inhibitors

Researchers from the National Institutes of Health (NIH) and Cornell University in the U.S. just described several new inhibitors of human coronavirus spike proteins by screening a library of approved drugs with SARS-S and MERS-S pseudotyped particle entry assays. Their exciting findings are currently available on the bioRxiv preprint server.

13 Jul 2020

Bat research critical to help predict and prevent the next pandemic

The current SARS-CoV-2 pandemic has a likely connection to bats, and the next viral outbreak probably will too, unless scientists can quickly learn more about the thousands of viruses carried by one of the most diverse mammals on the planet.

13 Jul 2020

New chemical could potentially lead to a cure for neglected tropical diseases

Scientists say they are a step closer to developing a drug to kill the trypanosome parasite that causes human African trypanosomiasis, otherwise known as sleeping sickness, paving the way for a potential cure.

13 Jul 2020

Long-studied protein can be used as biomarker for traumatic brain injury

Scientists at the Walter Reed Army Institute for Research have recently demonstrated that cathepsin B, a well-studied protein important to brain development and function, can be used as biomarker, or indicator of severity, for traumatic brain injury.

13 Jul 2020

Novel drug could enable the immune system to attack ovarian cancer

A drug known as SP-2577 could help enable the body's own immune system to attack ovarian cancer, according to a study led by the Translational Genomics Research Institute, an affiliate of City of Hope.

13 Jul 2020

New opioid medication may slow the progression of osteoarthritis

A novel preclinical study by Keck Medicine of USC researchers, published in Arthritis & Rheumatology, reveals that a potential new opioid medication may have the ability to slow the progression of osteoarthritis while being less addictive than commonly prescribed opioid drugs.

13 Jul 2020

Breakthrough discovery could lead to ‘kinder’ treatments for childhood bone cancer

Researchers at the University of East Anglia and University of Manchester have made an important breakthrough that could lead to ‘kinder’ treatments for children with bone cancer, and save lives.

13 Jul 2020

First extensive review of COVID-19's effects on all affected organs outside the lungs

After only a few days caring for critically ill COVID-19 patients at the start of the outbreak in New York City, Aakriti Gupta, MD, realized that this was much more than a respiratory disease.

12 Jul 2020

Drugs News and Research

Investigational antidepressant PT150 shows antiviral activity against SARS-CoV-2

Researchers characterize how changes in glioblastoma cells influence different drug effects

Dual inhibitor therapy may be safer for CLL patients, Moffitt study shows

Absolute Antibody and University of Zurich partner to offer novel SARS-CoV-2 sybodies

Researcher and health research journalist point out biased misinformation on coronavirus

Researchers review scientific articles on the role of zinc in COVID-19 prevention

Compound in pickled capers can directly regulate proteins required for bodily processes

Researchers uncover new mechanism for designing antiviral drugs for dengue virus

People with accelerated biological age at increased risk of COVID-19 symptom severity and mortality

New substance library established to accelerate the systematic development of drugs

COVID-19 – researchers sum up the “Tsunami” of information

Scientists discover common molecular feature found in SARS-CoV-2 neutralizing antibodies

Study identifies three novel broad-spectrum SARS-CoV-2 cell entry inhibitors

Bat research critical to help predict and prevent the next pandemic

New chemical could potentially lead to a cure for neglected tropical diseases

Long-studied protein can be used as biomarker for traumatic brain injury

Novel drug could enable the immune system to attack ovarian cancer

New opioid medication may slow the progression of osteoarthritis

Breakthrough discovery could lead to ‘kinder’ treatments for childhood bone cancer

First extensive review of COVID-19's effects on all affected organs outside the lungs

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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