Immune System News and Research

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Combining epigenetic drugs with immunotherapies may provide additional clinical benefit to cancer patients

Recent data suggest that epigenetic therapies are likely to provide additional clinical benefit to cancer patients when rationally combined with immunotherapeutic drugs, according to a review published in Clinical Cancer Research, a journal of the American Association for Cancer Research.

15 Sep 2015

Better treatment could be on the horizon for Myasthenia Gravis

Myasthenia Gravis (MG) is a debilitating and potentially deadly disease that can afflict anyone, characterized by severe muscle weakness, affecting control of facial expressions, arm and leg movements, chewing, swallowing, coughing and breathing. There is no cure, only treatment.

14 Sep 2015

UNC scientists create smarter immune cells to treat Parkinson's disease

As a potential treatment for Parkinson's disease, scientists at the University of North Carolina at Chapel Hill have created smarter immune cells that produce and deliver a healing protein to the brain while also teaching neurons to begin making the protein for themselves.

14 Sep 2015

NanoString announces key initiatives to expand market for nCounter Analysis System, related product portfolio

At a meeting with analysts and investors today, members of the senior management team of NanoString Technologies, Inc., a provider of life science tools for translational research and molecular diagnostic products, plan to unveil the company’s strategic roadmap to drive continued growth and expand the market for its nCounter Analysis System and the related product portfolio.

From NanoString Technologies 14 Sep 2015

Caltech researchers find antibody that can detect, neutralize HIV viruses in infected patients

Proteins called broadly neutralizing antibodies (bNAbs) are a promising key to the prevention of infection by HIV, the virus that causes AIDS. bNAbs have been found in blood samples from some HIV patients whose immune systems can naturally control the infection.

14 Sep 2015

Genetic mutations in deadly Ebola virus appear to block antibody-based treatments

Genetic mutations called "escape variants" in the deadly Ebola virus appear to block the ability of antibody-based treatments to ward off infection, according to a team of U.S. Army scientists and collaborators. Their findings, published online this week in the journal Cell Reports, have implications for the continued development of therapeutics to treat Ebola virus disease, which has claimed the lives of over 11,000 people in West Africa since last year.

14 Sep 2015

Uninsured, Medicaid stroke victims experience worse medical outcomes than patients with private insurance

Stroke victims who use Medicaid or are uninsured were more likely to die, stay hospitalized longer and have worse medical outcomes than patients with private insurance, a study by University of Florida Health researchers has found.

14 Sep 2015

New UCLA study finds novel approach that may help delay declines in health

Why do some people remain healthy into their 80s and beyond, while others age faster and suffer serious diseases decades earlier? New research led by UCLA life scientists may produce a new way to answer that question -- and an approach that could help delay declines in health.

14 Sep 2015

nCounterRNA:Protein pancancer immune profiling panel launched by NanoString

NanoString Technologies, Inc., a provider of life science tools for translational research and molecular diagnostic products, today announced the commercial launch of the nCounter® RNA:Protein PanCancer Immune Profiling Panel

From NanoString Technologies 11 Sep 2015

Penn Medicine researchers show that DNA editing errors can lead to cancer

Sometimes when the immune system makes small mistakes, the body amplifies its response in a big way: Editing errors in the DNA of developing T and B cells can cause blood cancers. Now, researchers from the Perelman School of Medicine, University of Pennsylvania have shown that when the enzyme key to cutting and pasting segments of DNA hits so-called "off-target" spots on a chromosome, the development of immune cells can lead to cancer in animal models.

11 Sep 2015

New collaboration may allow researchers to develop potential gene therapies for pediatric diseases

A new collaboration between Seattle Children's Research Institute and bluebird bio, Inc., a biotechnology company based in Cambridge, Mass. and Seattle, will allow researchers to develop potentially transformative gene therapies for severe genetic and rare pediatric diseases. The collaboration supports pediatric researchers in Seattle who will work with bluebird bio scientists and the company's gene editing technology to research potential cures for genetic pediatric diseases.

11 Sep 2015

Targeting exhausted immune cells may change prognosis for leukemia relapse patients after transplant

Targeting exhausted immune cells may change the prognosis for patients with acute myeloid leukemia (AML) relapse after a stem cell transplant, according to Penn State College of Medicine researchers.

11 Sep 2015

Study may help scientists to better understand complications caused by drug therapy in kidney transplant patients

New research will help scientists and medical professionals to better understand the long-term complications caused by an immunosuppressant drug used to treat thousands of kidney transplant patients.

11 Sep 2015

Inhibition of Tyk2 enzyme promotes anti-cancer activity

Tyrosine kinase 2 (Tyk2) is an enzyme involved in intracellular signalling and has an important role in activating the immune system.

11 Sep 2015

BerGenBio honored with Nordic Stars Award for innovation in Nordic life science community

BerGenBio AS ("BerGenBio" or the "Company"), an oncology biopharmaceutical company, today announces that it has been awarded one of this year's Nordic Stars Awards at the Nordic Life Science Days 2015 conference held in Stockholm, Sweden on 9-10 September, 2015.

11 Sep 2015

Northwestern University nanoscientist wins Raymond and Beverly Sackler Prize in Convergence Research

Northwestern University scientist Chad A. Mirkin, one of the world's leaders in nanotechnology research and its application, has been awarded the inaugural $400,000 Raymond and Beverly Sackler Prize in Convergence Research from the National Academy of Sciences.

10 Sep 2015

First patient dosed in long term-safety extension study of Resolaris for adult patients with FSHD

aTyr Pharma, Inc., a biotherapeutics company engaged in the discovery and development of Physiocrine-based therapeutics to address severe rare diseases, today announced that the first patient has been dosed in a newly initiated long term-safety extension study of Resolaris for adult patients with facioscapulohumeral muscular dystrophy (FSHD), a rare and severe genetic myopathy for which there are currently no approved treatments.

10 Sep 2015

CureVac announces official launch of U.S. operations in Cambridge, MA

CureVac, a clinical-stage biopharmaceutical company pioneering the field of mRNA-based technology, today announced the official launch of its U.S. operations in Cambridge, MA, as the company advances the development of its proprietary mRNA platform technology and multiple, clinical-stage mRNA therapeutics and vaccines.

10 Sep 2015

Healthy adults who receive flu vaccination may also help protect older adults at higher risk for flu-related complications

Healthy adults who get the flu vaccine may help protect not only themselves but also older adults in their community at higher risk for serious complications from influenza, suggest findings from a new study published in Clinical Infectious Diseases. Based on a national sample of more than 3 million people across eight flu seasons, researchers observed that seniors were up to 21 percent less likely to be diagnosed with flu-related illness if they lived in areas where more adults under 65 were immunized.

10 Sep 2015

Innovative vaccine therapy shows promise against glioblastoma brain tumors

An innovative vaccine therapy developed at Roswell Park Cancer Institute is being tested in a multisite clinical trial involving 50 patients with newly diagnosed glioblastoma brain tumors. The phase II study, now accruing patients at both Roswell Park and the Cleveland Clinic, will assess the effectiveness of the SurVaxM vaccine in combination with standard chemotherapy as treatment for this often-fatal cancer.

10 Sep 2015

Immune System News and Research

Combining epigenetic drugs with immunotherapies may provide additional clinical benefit to cancer patients

Better treatment could be on the horizon for Myasthenia Gravis

UNC scientists create smarter immune cells to treat Parkinson's disease

NanoString announces key initiatives to expand market for nCounter Analysis System, related product portfolio

Caltech researchers find antibody that can detect, neutralize HIV viruses in infected patients

Genetic mutations in deadly Ebola virus appear to block antibody-based treatments

Uninsured, Medicaid stroke victims experience worse medical outcomes than patients with private insurance

New UCLA study finds novel approach that may help delay declines in health

nCounterRNA:Protein pancancer immune profiling panel launched by NanoString

Penn Medicine researchers show that DNA editing errors can lead to cancer

New collaboration may allow researchers to develop potential gene therapies for pediatric diseases

Targeting exhausted immune cells may change prognosis for leukemia relapse patients after transplant

Study may help scientists to better understand complications caused by drug therapy in kidney transplant patients

Inhibition of Tyk2 enzyme promotes anti-cancer activity

BerGenBio honored with Nordic Stars Award for innovation in Nordic life science community

Northwestern University nanoscientist wins Raymond and Beverly Sackler Prize in Convergence Research

First patient dosed in long term-safety extension study of Resolaris for adult patients with FSHD

CureVac announces official launch of U.S. operations in Cambridge, MA

Healthy adults who receive flu vaccination may also help protect older adults at higher risk for flu-related complications

Innovative vaccine therapy shows promise against glioblastoma brain tumors

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