Efficacy News and Research

RSS

Study findings question benefit of giving sedatives before surgery for patients under general anesthesia

Although sedatives are often administered before surgery, a randomized trial finds that among patients undergoing elective surgery under general anesthesia, receiving the sedative lorazepam before surgery, compared with placebo or no premedication, did not improve the self-reported patient experience the day after surgery, but was associated with longer time till removal off a breathing tube (extubation) and a lower rate of early cognitive recovery, according to a study in the March 3 issue of JAMA.

4 Mar 2015

Common antidepressant medications not helpful for people with mood, anxiety disorders

Studies indicate that the majority of people with mood and anxiety disorders who receive the most commonly prescribed class of antidepressant medications, Selective Serotonin Reuptake Inhibitors or SSRI's, are not helped by these medications. SSRIs are designed to increase serotonin, a neurotransmitter in the brain that is key to maintenance of mood.

4 Mar 2015

World first: Antimicrobial copper supermarket trolleys

In a world first, a Brazilian supermarket has introduced supermarket trolleys with antimicrobial copper handles to help reduce the spread of disease-causing pathogens.

3 Mar 2015

Chrono Therapeutics gets support to develop SmartStop device for smoking cessation

Chrono Therapeutics, a pioneer in digital drug products, today announced an investment by Rock Health, the leading seed fund in digital health, to support the advancement of Chrono's SmartStop programmable transdermal drug delivery system and real-time behavioral support program for smoking cessation.

3 Mar 2015

Breakthrough treatment option for men with benign prostatic hyperplasia

Men with benign prostatic hyperplasia (BPH), a condition in which the prostate is enlarged but not cancerous, have a new, breakthrough treatment option that is less invasive and has fewer complications than other minimally invasive treatments, such as transurethral resection of the prostate and surgical options, according to research presented at the Society of Interventional Radiology's Annual Scientific Meeting.

3 Mar 2015

Extending use of bupropion before quitting reduces smoking behavior

Smokers may be more likely to successfully quit their habit if simple adjustments were made to how an existing anti-smoking medication is prescribed, according to a new study by a University at Buffalo research team.

3 Mar 2015

MIT researchers develop new nanodevice that can help overcome drug resistance

Chemotherapy often shrinks tumors at first, but as cancer cells become resistant to drug treatment, tumors can grow back. A new nanodevice developed by MIT researchers can help overcome that by first blocking the gene that confers drug resistance, then launching a new chemotherapy attack against the disarmed tumors.

3 Mar 2015

Taiho announces submission of TAS-102 MAA to EMA for treatment of mCRC

Taiho Pharma Europe Ltd., a subsidiary of Japan based Taiho Pharmaceutical Co., Ltd., announced that it has submitted a Marketing Authorisation Application to the European Medicines Agency for TAS-102 (nonproprietary names: trifluridine and tipiracil hydrochloride), an oral combination anticancer drug intended for use in the treatment of refractory metastatic colorectal cancer (mCRC).

2 Mar 2015

Transition completes enrolment of patients in ELND005 Phase 2 study for treatment of AD patients

Transition Therapeutics Inc. announced that its wholly owned subsidiary, Transition Therapeutics Ireland Limited completed enrolment of the Phase 2 clinical study evaluating neuropsychiatric drug candidate ELND005 as a treatment for agitation and aggression in patients with mild, moderate and severe Alzheimer's disease ("AD").

2 Mar 2015

Bielefeld University chemists develop copper molecule that could help prevent spread of cancer

Chemists at Bielefeld University have developed a molecule containing copper that binds specifically with DNA and prevents the spread of cancer. First results show that it kills the cancer cells more quickly than cisplatin - a widely used anti-cancer drug that is frequently administered in chemotherapy.

2 Mar 2015

Pediatricians, health care providers encounter requests to postpone vaccinations

Pediatricians are facing increasing pressure from some parents who want to spread out the recommended vaccine schedule for their children by postponing vaccines, pointing to a need for improved programs that support timely vaccinations, according to a new study by researchers at the University of Colorado School of Medicine at the Anschutz Medical Campus.

2 Mar 2015

Mundipharma launches Remsima® (infliximab), a new-generation value-based monoclonal antibody, in six European markets

Mundipharma International Limited’s network of independent associated companies are launching Remsima® (infliximab) this month in Germany, Italy, UK, Netherlands, Belgium and Luxembourg following expiry of the relevant patents and Supplementary Protection Certificates, having secured distribution rights from Celltrion Healthcare Hungary Kft for Remsima in these markets.

1 Mar 2015

Novel financing technique may unlock funding for developing 'orphan' drugs to treat rare diseases

A paper published today, "Financing translation: Analysis of the NCATS rare-diseases portfolio" in Science Translational Medicine, demonstrates the potential of a new financing technique to reduce the risk associated with investing in the treatment of new diseases and potentially unlock new levels of funding for developing so-called "orphan" drugs.

28 Feb 2015

New pharmacological compounds block nerve cell damage in mouse models of MS

A newly characterized group of pharmacological compounds block both the inflammation and nerve cell damage seen in mouse models of multiple sclerosis, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published online this week in the journal Nature Neuroscience.

28 Feb 2015

Perceived cost affects placebo response in Parkinson’s disease

Patients with Parkinson’s disease may gain a greater benefit from a placebo treatment if they believe it to be expensive, research suggests.

27 Feb 2015

NICE recommends transurethral resection in saline system as the new gold standard for transurethral resection of the prostate

New guidance has been released today by the National Institute for Health and Care Excellence (NICE) recommending Olympus Medical’s transurethral resection in saline (TURis) system for use in surgery to reduce the size of enlarged prostate glands in men. NICE published the guidance in light of the potential it offers NHS hospitals to realise substantial cost savings of £285-£375 per patient whilst also improving patient outcomes.

From Evident Corporation - Life Sciences 27 Feb 2015

FDA approves LILETTA (levonorgestrel-releasing intrauterine system) to prevent pregnancy

Actavis plc, a leading global specialty pharmaceutical company, and Medicines360, a nonprofit women's health pharmaceutical company, today announced the approval of LILETTA (levonorgestrel-releasing intrauterine system) by the U.S. Food and Drug Administration for use by women to prevent pregnancy for up to three years.

27 Feb 2015

NIAID partners with Liberian government to test ZMapp drug for Ebola virus disease

In partnership with the Liberian government, the National Institute of Allergy and Infectious Diseases today launched a clinical trial to obtain safety and efficacy data on the investigational drug ZMapp as a treatment for Ebola virus disease. The study, which will be conducted in Liberia and the United States, is a randomized controlled trial enrolling adults and children with known Ebola virus infection.

27 Feb 2015

ERT signs definitive agreement to acquire PHT

ERT, a leading global solution provider for high-quality patient safety and efficacy endpoint data collection, and PHT Corporation, the eClinical innovator leading the adoption of patient-driven mobile apps for improved clinical research, announced today that they have signed a definitive agreement under which ERT will acquire PHT.

27 Feb 2015

Study shows efficacy of YONDELIS (trabectedin) in patients with soft-tissue sarcoma

PharmaMar announced that the European Journal of Cancer published online data from a large retrospective study with soft-tissue sarcoma (STS) patients carried out at 25 French centers confirming that in routine practice YONDELIS (trabectedin) shows comparable or better clinical outcomes than those observed in clinical trials.

27 Feb 2015

Efficacy News and Research

Study findings question benefit of giving sedatives before surgery for patients under general anesthesia

Common antidepressant medications not helpful for people with mood, anxiety disorders

World first: Antimicrobial copper supermarket trolleys

Chrono Therapeutics gets support to develop SmartStop device for smoking cessation

Breakthrough treatment option for men with benign prostatic hyperplasia

Extending use of bupropion before quitting reduces smoking behavior

MIT researchers develop new nanodevice that can help overcome drug resistance

Taiho announces submission of TAS-102 MAA to EMA for treatment of mCRC

Transition completes enrolment of patients in ELND005 Phase 2 study for treatment of AD patients

Bielefeld University chemists develop copper molecule that could help prevent spread of cancer

Pediatricians, health care providers encounter requests to postpone vaccinations

Mundipharma launches Remsima® (infliximab), a new-generation value-based monoclonal antibody, in six European markets

Novel financing technique may unlock funding for developing 'orphan' drugs to treat rare diseases

New pharmacological compounds block nerve cell damage in mouse models of MS

Perceived cost affects placebo response in Parkinson’s disease

NICE recommends transurethral resection in saline system as the new gold standard for transurethral resection of the prostate

FDA approves LILETTA (levonorgestrel-releasing intrauterine system) to prevent pregnancy

NIAID partners with Liberian government to test ZMapp drug for Ebola virus disease

ERT signs definitive agreement to acquire PHT

Study shows efficacy of YONDELIS (trabectedin) in patients with soft-tissue sarcoma

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News