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SARS-CoV-2 virus uses a multipronged strategy to avoid detection by the immune system

Severe symptoms of COVID-19, leading often to death, are thought to result from the patient's own acute immune response rather than from damage inflicted directly by the virus.

13 May 2021

Comprehensive blood atlas of COVID-19 identifies hallmarks of disease severity

Researchers in the UK have presented a multi-omics integrated blood atlas that delineates the host immune response in patients with coronavirus disease 2019 (COVID-19) of varying severity, providing a unique reference resource for the interpretation of datasets generated from interventional trials.

13 May 2021

Pfizer-BioNTech COVID-19 vaccine effective in patients with myeloproliferative neoplasms

Researchers in the UK have provided evidence that Pfizer-BioNTech’s coronavirus disease 2019 (COVID-19) vaccine induces effective immune responses in patients with myeloproliferative neoplasms.

13 May 2021

Researchers identify six “words” used by specific immune cells to call up immune defense genes

UCLA life scientists have identified six "words" that specific immune cells use to call up immune defense genes -- an important step toward understanding the language the body uses to marshal responses to threats.

13 May 2021

Scientists unveil new Ebola virus vaccine design

Scientists at Scripps Research have unveiled a new Ebola virus vaccine design, which they say has several advantages over standard vaccine approaches for Ebola and related viruses that continue to threaten global health.

13 May 2021

Inexpensive test for rapid detection of COVID-19 with 90% accuracy

A low-cost, rapid diagnostic test for COVID-19 developed by Penn Medicine provides COVID-19 results within four minutes with 90 percent accuracy.

12 May 2021

Research provides new insight into anesthesia-associated tau spreading in the brain

During the development and progression of Alzheimer's disease, a protein called tau accumulates and spreads in the brain.

12 May 2021

Study could help understand how Tuberous Sclerosis Complex arises

Tuberous Sclerosis Complex (TSC) affects between one and two of every 10,000 new-born babies. This genetic disease leads to the formation of benign tumors which can massively impair the proper functioning of vital organs such as the kidneys, the liver and the brain.

12 May 2021

Study examines a pathway responsible for the formation of tau tangles in the brain

Since the discovery of Alzheimer's disease over a century ago, two hallmarks of the devastating illness have taken center stage.

12 May 2021

Researchers develop a hairpin-shaped bicyclic peptide to fight cancer

The inhibition of pathological protein-protein interactions is a promising approach for treating a large number of diseases, including many forms of cancer.

12 May 2021

CNIO researchers unravel why motor neurons die in ALS patients

In Amyotrophic Lateral Sclerosis (ALS), the progressive death of neurons that control body movement leads to paralysis of muscles in the limbs and gradually of the whole body, which ultimately makes it impossible to breathe. ALS is currently untreatable, and its cause is unknown.

12 May 2021

Researchers investigate antibodies that best neutralize SARS-CoV-2 in COVID-19 patients

The COVID-19 pandemic has now claimed over 2 million deaths worldwide, and this number is only increasing. In response, health agencies have rolled out tests to diagnose and understand the disease.

12 May 2021

Novel chip-based antigen test can provide ultrasensitive detection of SARS-CoV-2, influenza A

Researchers at UC Santa Cruz have developed a novel chip-based antigen test that can provide ultrasensitive detection of SARS-CoV-2 and influenza A, the viruses that cause COVID-19 and flu, respectively.

12 May 2021

New class of anti-cancer compounds effectively kills liver and breast cancer cells

A team of Oregon State University scientists has discovered a new class of anti-cancer compounds that effectively kill liver and breast cancer cells.

12 May 2021

Spread of minority SARS-CoV-2 variants in New York City

Viruses mutate to survive. But not all mutations are beneficial to the virus. On the other hand, some mutations such as N501Y and E484K on the spike protein propelled specific severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants to ‘variant of concern’ status, due to their ability to increase transmission and weaken the response of neutralizing antibodies.

12 May 2021

Evolutionary-spreading model predicts another devastating COVID-19 peak around July 2021

The emergence of this variant highlighted the uneven pace of mutation and selection of variants. New bioinformatics tools are the need of the hour to clarify this and confirm a dynamic evolution by tracking the mutation rates of the spike protein. It generally takes 1 – 6 months for current variants causing COVID-19 case peaks and deaths to survive the pressure of selection.

11 May 2021

Protein C News and Research

SARS-CoV-2 virus uses a multipronged strategy to avoid detection by the immune system

Comprehensive blood atlas of COVID-19 identifies hallmarks of disease severity

Pfizer-BioNTech COVID-19 vaccine effective in patients with myeloproliferative neoplasms

Researchers identify six “words” used by specific immune cells to call up immune defense genes

Scientists unveil new Ebola virus vaccine design

Inexpensive test for rapid detection of COVID-19 with 90% accuracy

Research provides new insight into anesthesia-associated tau spreading in the brain

Study could help understand how Tuberous Sclerosis Complex arises

Study examines a pathway responsible for the formation of tau tangles in the brain

Researchers develop a hairpin-shaped bicyclic peptide to fight cancer

CNIO researchers unravel why motor neurons die in ALS patients

Researchers investigate antibodies that best neutralize SARS-CoV-2 in COVID-19 patients

Novel chip-based antigen test can provide ultrasensitive detection of SARS-CoV-2, influenza A

New class of anti-cancer compounds effectively kills liver and breast cancer cells

Spread of minority SARS-CoV-2 variants in New York City

Evolutionary-spreading model predicts another devastating COVID-19 peak around July 2021

Low dose of a four-drug combination helps prevent cancer metastasis in mice

An intranasal COVID-19 vaccine elicits long-lasting immunity against SARS-CoV-2 variants in vivo

Researchers design compounds that prevent SARS-CoV-2 entry in human lung cells

Novel 'CopyCatcher' detects when precise copying of genetic information takes place in cells

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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