Efficacy News and Research

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Primary care nurse-led intervention improves physical activity among older adults

A primary care nurse-delivered intervention can lead to sustained increases in physical activity (PA) among older adults, according to an article published by Tess Harris of St George's University of London, and colleagues in this week's PLOS Medicine. The trial was funded by the National Institute for Health Research.

18 Feb 2015

Second-line bosutinib well tolerated by Japanese patients

Phase I/II clinical trial data support the use of bosutinib as second- or third-line tyrosine kinase inhibitor therapy in Japanese patients with Philadelphia chromosome-positive chronic myeloid leukaemia.

17 Feb 2015

USPTO issues Notice of Allowance to Can-Fite BioPharma for psoriasis patent

Can-Fite BioPharma Ltd., a biotechnology company with a pipeline of proprietary small molecule drugs that are being developed to treat inflammatory diseases, cancer and sexual dysfunction, announced today that it has received a Notice of Allowance from the U.S. Patent and Trademark Office for CF101 in the treatment of psoriasis.

17 Feb 2015

BGRF announces publication of research into personalising nootropic drugs using in silico prediction methods

The Biogerontology Research Foundation (BGRF), a UK-based charity committed to the support of aging research to address the challenges of a rapidly aging population and to reduce the impact of disease on future generations, announces the publication of research into personalising nootropic drugs using in silico prediction methods.

17 Feb 2015

Hospira announces launch of first biosimilar monoclonal antibody in Europe

Hospira, Inc., a world leader in the development of biosimilar therapies, today announced the launch of the first biosimilar monoclonal antibody (mAb), Inflectra (infliximab), in major European markets.

16 Feb 2015

Cervarix effective against other common cancer-causing HPVs

According to a multinational clinical trial involving nearly 20,000 young women, the human papilloma virus vaccine, Cervarix, not only has the potential to prevent cervical cancer, but was effective against other common cancer-causing human papillomaviruses, aside from just the two HPV types, 16 and 18, which are responsible for about 70 percent of all cases.

15 Feb 2015

New antibody shows promise in increasing survival for patients suffering from influenza, pneumonia

Scientists from NTU Singapore, the world's No. 1 young university, have developed an antibody which boosts the survival chances for patients suffering from influenza and pneumonia.

14 Feb 2015

Omega-3 could supplement anti-VEGF treatment in AMD

Pilot study findings suggest that taking omega-3 fatty acid supplements could increase the efficacy or reduce the needed frequency of anti-vascular endothelial growth factor treatment in patients with exudative age-related macular degeneration.

13 Feb 2015

Novel image-analysis technique improves breast cancer detection and diagnosis

Researchers at the University of Oklahoma have developed an image-analysis technique that is designed to improve breast cancer detection and diagnosis.

13 Feb 2015

Biomedical use of gold nanotubes demonstrated in mouse model of human cancer

Scientists have shown that gold nanotubes have many applications in fighting cancer: internal nanoprobes for high-resolution imaging; drug delivery vehicles; and agents for destroying cancer cells.

13 Feb 2015

Landmark stroke studies presented at ISC, published in NEJM suggest new treatment protocol on the horizon

Research presented today at the International Stroke Conference (ISC) in Nashville, Tenn. and published online in The New England Journal of Medicine (NEJM) found that the addition of the Solitaire™ Device stent thrombectomy procedure to current pharmaceutical treatment significantly reduced disability in patients suffering stroke.

From Medtronic 13 Feb 2015

Jazz Pharmaceuticals to present defibrotide results for hepatic VOD at BMT Tandem meetings

Jazz Pharmaceuticals plc announced today that researchers will present data on the use of defibrotide, an investigational medicine being studied in the United States (U.S.) for the treatment of hepatic veno-occlusive disease (VOD), a rare, potentially life-threatening, early complication in patients undergoing hematopoietic stem-cell transplantation (HSCT) therapy.

13 Feb 2015

Elusys presents positive results of obiltoxaximab for treating inhalational anthrax, post-exposure prophylaxis

Elusys Therapeutics, Inc. (Elusys), a biopharmaceutical company developing antibody therapies to treat infectious disease, presented data demonstrating that obiltoxaximab (ETI-204) demonstrated a statistically significant survival benefit across a range of disease severity in animal model studies assessing treatment of inhalational anthrax, as well as effectiveness in post-exposure prophylaxis.

13 Feb 2015

Health Canada to review Cipher’s self-adhesive medicated plaster, Beteflam Patch

Cipher Pharmaceuticals Inc. (NASDAQ: CPHR; TSX:CPH) ("Cipher" or "the Company") today announced that the Beteflam Patch (previously called the Betesil® Patch) has been accepted for review by Health Canada.

13 Feb 2015

Researchers identify molecular pathways associated with distinct subsets of SSc patients

For years, doctors have been baffled about why some patients with systemic sclerosis (SSc) respond to therapy while others do not.

12 Feb 2015

Endovascular treatment can improve patient outcomes after acute ischemic stroke

Canadian researchers have completed an international randomized controlled trial showing that a clot retrieval procedure, known as endovascular treatment (ET), can dramatically improve patient outcomes after an acute ischemic stroke. The study, led by researchers at the University of Calgary's Hotchkiss Brain Institute (HBI), shows a dramatic improvement in outcomes and a reduction in deaths from stroke.

12 Feb 2015

UT Southwestern gets NCI grant to establish Heavy Ion Radiation Therapy Research Center in US

UT Southwestern Medical Center is leading a Texas consortium of researchers to establish the country's first National Center for Heavy Ion Radiation Therapy that could provide clinical care and research using heavy particles for innovative new cancer treatments.

12 Feb 2015

Studies show neurointerventional surgery reduces stroke mortality rate by 50%

Two new clinical trials on the treatment of stroke (ESCAPE and EXTEND IA) demonstrate that neurointerventional surgery significantly increases the number of patients who are able to live independently without major neurological disabilities.

12 Feb 2015

NanoSmart's ANA-conjugated liposomal doxorubicin receives FDA Orphan Drug Designation

NanoSmart Pharmaceuticals, Inc., a private pharmaceutical company developing nanoparticle drug delivery platforms, has received Orphan Drug Designation from the Food and Drug Administration for one of its lead candidates, antinuclear antibody (ANA) conjugated liposomal doxorubicin.

11 Feb 2015

FDA advisory committees to review Amgen's talimogene laherparepvec for metastatic melanoma treatment

Amgen announced today that the Cellular, Tissue and Gene Therapies Advisory Committee and the Oncologic Drugs Advisory Committee of the U.S. Food and Drug Administration will jointly review the Company's Biologics License Application (BLA) for talimogene laherparepvec.

11 Feb 2015

Efficacy News and Research

Primary care nurse-led intervention improves physical activity among older adults

Second-line bosutinib well tolerated by Japanese patients

USPTO issues Notice of Allowance to Can-Fite BioPharma for psoriasis patent

BGRF announces publication of research into personalising nootropic drugs using in silico prediction methods

Hospira announces launch of first biosimilar monoclonal antibody in Europe

Cervarix effective against other common cancer-causing HPVs

New antibody shows promise in increasing survival for patients suffering from influenza, pneumonia

Omega-3 could supplement anti-VEGF treatment in AMD

Novel image-analysis technique improves breast cancer detection and diagnosis

Biomedical use of gold nanotubes demonstrated in mouse model of human cancer

Landmark stroke studies presented at ISC, published in NEJM suggest new treatment protocol on the horizon

Jazz Pharmaceuticals to present defibrotide results for hepatic VOD at BMT Tandem meetings

Elusys presents positive results of obiltoxaximab for treating inhalational anthrax, post-exposure prophylaxis

Health Canada to review Cipher’s self-adhesive medicated plaster, Beteflam Patch

Researchers identify molecular pathways associated with distinct subsets of SSc patients

Endovascular treatment can improve patient outcomes after acute ischemic stroke

UT Southwestern gets NCI grant to establish Heavy Ion Radiation Therapy Research Center in US

Studies show neurointerventional surgery reduces stroke mortality rate by 50%

NanoSmart's ANA-conjugated liposomal doxorubicin receives FDA Orphan Drug Designation

FDA advisory committees to review Amgen's talimogene laherparepvec for metastatic melanoma treatment

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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