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Dominant SARS-CoV-2 strain A2a binds more easily to ACE2 receptors

The COVID-19 pandemic has affected almost all countries across the world, and India is no exception. Researchers have found that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has undergone several mutations with time.

28 Apr 2020

Important insights into COVID-19 for worldwide strategic planning

Researchers in China and the United States have analyzed cases of early severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and their close contacts to provide further insights into the disease’s transmission and severity and the effectiveness of control measures.

28 Apr 2020

New approach for easier detection of SARS-CoV-2 via swabs and saliva

A recent Israeli study points toward Reverse Transcription Loop-Mediated Isothermal Amplification (RT-LAMP) as a potentially effective tool for acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on-the-spot detection by using swabs or saliva – addressing the community need for simple surveillance.

28 Apr 2020

Albany, Wisconsin researchers look for molecular clues to fight COVID-19

In the center of the COVID-19 pandemic, hospitals are racing to maintain quality care for patients with severe disease while facing a shortage of resources and limited understanding of the novel coronavirus.

28 Apr 2020

Gustave Roussy and Biognosys Announce Partnership

The severe pneumonitis in patients infected by SARS-Cov-2 requires prolonged treatment in intensive care units with mechanical ventilation.

From Biognosys 28 Apr 2020

Researchers describe an underlying biological basis for mylagic encephalomyelitis/chronic fatigue syndrome

Mylagic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a disabling and complex illness. Affected persons often cannot pursue ordinary activities -- physical or mental -- because of an incapacitating loss of energy and other symptoms, and may find themselves confined to bed or house-bound for years.

28 Apr 2020

International collaborators propose a new ranking scheme to classify SARS-CoV-2

In November of 2019--likely, even earlier--a tiny entity measuring just a few hundred billionths of a meter in diameter began to tear apart human society on a global scale.

28 Apr 2020

New device combined with mechanical ventilation can help improve treatment outcomes for COVID-19

A device designed at the University of Pittsburgh could help improve outcomes as a treatment for COVID-19 when used in conjunction with non-invasive or mechanical ventilation, and it recently received Emergency Use Authorization (EUA) from the U.S. Food and Drug Administration.

28 Apr 2020

COVID-19 can trigger serious inflammatory-related cardiovascular problems

The coronavirus disease (COVID-19) is potentially fatal for vulnerable populations like seniors who over 60 years old, and those with underlying medical conditions, like heart disease, diabetes, and lung disease. Reports show that patients are suffering from heart impairment caused by COVID-19. A new study sheds light on the effect of the novel coronavirus on the heart, causing cardiovascular problems, even in those without underlying heart conditions.

27 Apr 2020

Using neutralising antibodies in the fight against COVID-19

While many scientists and pharmaceutical companies are racing to develop a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine, there is also an urgent need for a coronavirus disease (COVID-19) treatment. The potent virus has now spread to 210 countries and territories, affecting more than 3.04 million people. Now, a team of German scientists is working on using antibodies to prevent and treat COVID-19.

27 Apr 2020

Study looks at outcomes of COVID‐19 during pregnancy

With the world at a standstill as the novel coronavirus SARS-CoV-2 spreads across the globe, governments are struggling to slow down its wrath. Worldwide public health responses and emergency measures have been implemented to stem the impact of the coronavirus disease (COVID-19).

27 Apr 2020

The approved dose of ivermectin alone not useful in treating COVID-19

A new paper published on the preprint server medRxiv in April 2020 shows that the use of the already approved drug ivermectin in clinical trials to treat severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)s not feasible. This contradicts earlier reports of its ability to suppress the virus in vitro.

27 Apr 2020

New, previously unknown form of familial cold urticaria discovered

Skin rash combined with head and joint pain: these are the symptoms which patients with familial (hereditary) cold urticaria develop when exposed to temperatures below 15 °C.

27 Apr 2020

Gut microbiota could predict severity of COVID-19

The COVID-19 pandemic is spreading to every corner of the world. But not everyone is falling sick at the same rate. A new study published on the preprint server medRxiv in April 2020 suggests that the composition of the gut microbiome could partially explain the difference in susceptibility. This adds a new dimension to what is currently known about the disease.

27 Apr 2020

SARS-CoV-2 readily infects human intestinal cells in a laboratory model

A new Dutch study available on bioRxiv uses differentiated human small intestinal organoids in vitro to demonstrate that intestinal epithelium supports the replication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and elicits a strong generic immune response.

27 Apr 2020

SARS-CoV-2 spike protein discovery could pave way for COVID-19 vaccine

Researchers at the Indian Institute of Technology, Guwahati, have made an important discovery about a viral fusion protein found on the surface of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that could help researchers develop a vaccine.

27 Apr 2020

Researchers re-purpose cancer-fighting artificial antibodies for COVID-19

Researcher Paula Bates, John Trent, and Don Miller developed a therapeutic drug that could potentially block the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) responsible for the COVID-19 pandemic. Their research was initially aimed at helping patients suffering from multiple types of cancer.

27 Apr 2020

Rice University looks to ‘trap and zap’ SARS-CoV-2 in wastewater

A team of researchers from Rice University has won a National Science Foundation (NSF) RAPID grant to adapt their wastewater nanotechnology project to help trap and inactivate the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), (which causes COVID-19 disease), in wastewater. This could help public health officials deal with the threat of disease transmission through wastewater.

27 Apr 2020

Recombinant protein produces neutralizing COVID-19 antibodies in primate model

A new study reports the induction of high levels of neutralizing antibodies to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus causing the current pandemic of COVID-19. This promising finding was reported on the preprint server bioRxiv on April 2020.

26 Apr 2020

Is the BCG vaccine really protective against COVID-19?

A new paper published on the preprint server medRxiv in April 2020 challenges the hypothesis that BCG vaccination confers some degree of protection against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes the pneumonic illness COVID-19.

26 Apr 2020