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Scientists awarded $1.3 million grant to study relationship between traumatic brain injury and dementia

The U.S. Department of Defense has awarded a team of scientists and physicians from leading health care institutions across Phoenix a $1.3 million grant over three years to study traumatic brain injury and its relationship to dementia.

4 Oct 2017

Biochemists discover genes that determine animal complexity

Genes which determine animal complexity – or what makes humans so much more complex than a fruit fly or a sea urchin – have been identified for the first time.

30 Sep 2017

Study identifies potential biomarker for onset, progression of MS

An article published in Experimental Biology and Medicine identifies Opioid Growth Factor (OGF) as a novel biomarker for the onset and progression of multiple sclerosis (MS).

27 Sep 2017

Researchers reveal reason for olfactory dysfunction in initial stage of Alzheimer's disease

A research team led by DGIST Professor Moon Cheil at the Department of Brain and Cognitive Sciences has identified the reason why the patients with the early stage of Alzheimer's fail to smell.

27 Sep 2017

Drug combination produces synergistic effect against growth of triple-negative breast cancer

In the hunt for novel treatments against an aggressive form of breast cancer, researchers combined a new protein inhibitor with a chemotherapy drug to create a powerful combination that resulted in cancer cell death.

26 Sep 2017

Researchers identify new mechanism that causes hallmark symptoms of Parkinson's disease

A KAIST research team has identified a new mechanism that causes the hallmark symptoms of Parkinson's disease, namely tremors, rigidity, and loss of voluntary movement.

26 Sep 2017

New pig model for stroke could accelerate drug discovery process

It is well-known in the medical field that the pig brain shares certain physiological and anatomical similarities with the human brain. So similar are the two that researchers at the University of Georgia's Regenerative Bioscience Center have developed the first U.S. pig model for stroke treatments, which will provide essential preclinical data and speed the drug discovery process.

26 Sep 2017

Novel gene therapy can inhibit, reverse multiple sclerosis in mouse models

Multiple sclerosis can be inhibited or reversed using a novel gene therapy technique that stops the disease's immune response in mouse models, University of Florida Health researchers have found.

21 Sep 2017

Scientists take important step toward gene therapy for deaf patients

Scientists at Oregon State University have taken an important step toward gene therapy for deaf patients by developing a way to better study a large protein essential for hearing and finding a truncated version of it.

19 Sep 2017

Scientists genetically engineer mice that display behavioral hallmarks of human bipolar disorder

Johns Hopkins researchers report they have genetically engineered mice that display many of the behavioral hallmarks of human bipolar disorder, and that the abnormal behaviors the rodents show can be reversed using well-established drug treatments for bipolar disorder, such as lithium.

18 Sep 2017

Researchers create chimera virus that allows study of molecules to treat cancers

Researchers from Instituto de Medicina Molecular Lisboa have created a chimera virus that allows the study of molecules to treat cancers caused by human herpesvirus infection in mice models of disease.

18 Sep 2017

Study shows how regular exercise, stress reduction could lead to better health in lupus patients

Waking up in the morning with the joint pain, swelling and stiffness that accompanies lupus doesn't exactly inspire a workout.

14 Sep 2017

Virginia Tech research provides new mechanistic insights into health benefits of olives and olive oil

The health benefits of olives-- and associated natural products such as olive oil--have long been recognized and touted by proponents of the Mediterranean diet.

13 Sep 2017

Cannabidiol appears to protect against long-term negative psychiatric effects of THC

A study reported Sept. 5 by neuroscientists at Indiana University finds that a non-psychoactive compound in cannabis called cannabidiol, or CBD, appears to protect against the long-term negative psychiatric effects of THC, the primary psychoactive ingredient in cannabis.

6 Sep 2017

Disruption of 'slow waves' can lead to cognitive decline similar to Alzheimer’s in mice

While unconscious during deep sleep, millions of neurons' activity travels across the cerebral cortex. This phenomenon, known as slow waves, is related to the consolidation of memory.

5 Sep 2017

Mayo Clinic research clarifies relationship between two genes that fuel neuroblastoma spread

For the first time, Mayo Clinic researchers and colleagues present data on how nervous system tumors, called neuroblastomas, spread. Their paper, published in Cancer Cell, clarifies the relationship between two genes that fuel the aggressive spread of neuroblastomas.

1 Sep 2017

Researchers use zebrafish animal model to explore drug-seeking behavior

As the opioid crisis escalates, the science behind addiction remains poorly understood. To address this need, researchers at University of Utah Health devised a system that allowed zebrafish, a small tropical fish, to self-administer doses of hydrocodone, an opioid commonly prescribed to people for pain.

26 Aug 2017

Research reveals underlying reason for intense pain in patients with shingles

Chickenpox is a typical childhood illness. In most cases, it is benign, and the symptoms disappear within ten days. However, its causative agent, Varicella zoster virus (VZV), remains in the organism forever. In some cases, the virus can be reactivated years later, causing a different disease known as herpes zoster, or shingles.

24 Aug 2017

Common obesity and diabetes drug could be used as novel way to lower brain pressure

Research led by the University of Birmingham, published today in Science Translational Medicine, has discovered that a drug commonly used to treat patients with either obesity or Type II diabetes could be used as a novel new way to lower brain pressure.

23 Aug 2017

Cortisol mediates communication between gut bacteria and brain metabolites, study suggests

Gut microbes have been in the news a lot lately. Recent studies show they can influence human health, behavior, and certain neurological disorders, such as autism.

21 Aug 2017

Animal Model News and Research

Scientists awarded $1.3 million grant to study relationship between traumatic brain injury and dementia

Biochemists discover genes that determine animal complexity

Study identifies potential biomarker for onset, progression of MS

Researchers reveal reason for olfactory dysfunction in initial stage of Alzheimer's disease

Drug combination produces synergistic effect against growth of triple-negative breast cancer

Researchers identify new mechanism that causes hallmark symptoms of Parkinson's disease

New pig model for stroke could accelerate drug discovery process

Novel gene therapy can inhibit, reverse multiple sclerosis in mouse models

Scientists take important step toward gene therapy for deaf patients

Scientists genetically engineer mice that display behavioral hallmarks of human bipolar disorder

Researchers create chimera virus that allows study of molecules to treat cancers

Study shows how regular exercise, stress reduction could lead to better health in lupus patients

Virginia Tech research provides new mechanistic insights into health benefits of olives and olive oil

Cannabidiol appears to protect against long-term negative psychiatric effects of THC

Disruption of 'slow waves' can lead to cognitive decline similar to Alzheimer’s in mice

Mayo Clinic research clarifies relationship between two genes that fuel neuroblastoma spread

Researchers use zebrafish animal model to explore drug-seeking behavior

Research reveals underlying reason for intense pain in patients with shingles

Common obesity and diabetes drug could be used as novel way to lower brain pressure

Cortisol mediates communication between gut bacteria and brain metabolites, study suggests

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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