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New treatment can improve the lives of patients with spinal cord injury

An international team of scientists headed by Grégoire Courtine at EPFL and CHUV and Aaron Phillips at the University of Calgary has developed a treatment that can dramatically improve the lives of patients with a spinal cord injury.

28 Jan 2021

Neurological and psychiatric complications six months after COVID-19 recovery

Researchers in the United Kingdom have aimed to determine the prevalence of patients who experience neurological and psychiatric conditions six months after recovering from COVID-19.

28 Jan 2021

Ebola survivors experienced a resurgence in antibody levels after recovery

A high proportion of survivors of Ebola experienced a resurgence in antibody levels nearly a year after recovery, a new University of Liverpool study has found.

27 Jan 2021

Certain malaria parasites use a mechanism to cross the blood–brain barrier

Malaria is one of the most common causes of death in children in Africa and is triggered by a small parasite that lives in the blood. When the parasite builds up in the blood vessels of the brain, it develops into one of the most dangerous forms of the disease, cerebral malaria.

27 Jan 2021

Inflammation of the brain gray matter decreases nerve-cell activity in mouse model

Damage to the brain gray matter plays an important role in the progression of multiple sclerosis. This study now shows that such damage can be caused by inflammatory reactions that lead to loss of synapses, which impairs neural activity.

27 Jan 2021

FDA takes action on alcohol-based hand sanitizers from Mexico

As part of the U.S. Food and Drug Administration's continuing efforts to protect consumers from potentially dangerous or subpotent hand sanitizers, the agency has placed all alcohol-based hand sanitizers from Mexico on a countrywide import alert to help stop products that appear to be in violation from entering the U.S. until the agency is able to review the products' safety.

26 Jan 2021

Researchers find microbiome-controlled anti-inflammatory subsets of astrocytes

Astrocytes are the most abundant type of cells within the central nervous system (CNS), but they remain poorly characterized.

26 Jan 2021

Negative childhood experience connected to relatively unfavorable living situation

An adverse upbringing often impairs people's circumstances and health in their adult years, especially for couples who have both had similar experiences.

21 Jan 2021

How does SARS-CoV-2 infect brain cells?

Researchers from the University of California San Francisco, Gladstone Institutes in the USA, and The Aga Khan University in Pakistan investigated if human neural cells can be infected by SARS-CoV-2.

20 Jan 2021

International consortium investigates specific cell signaling process across range of human diseases

Life in the digital age often throws a curveball when the signalling bars on our mobile phones drop or disappear altogether. Similarly, disruptions in the signalling networks of cells within the body can wreak havoc and lead to disease.

20 Jan 2021

Magnetic nanoparticles guide neurite growth in dopaminergic cells

Magnetic nanoparticles raise hopes of treatments for Parkinson’s.

19 Jan 2021

Can transgenic mice studies illuminate neurological complications associated with SARS-CoV-2 in humans?

The potentially deadly COVID-19 has not affected animals with corresponding severity. To understand the mechanism of severe disease, animal models have been used. This includes a mouse model that expresses human angiotensin-converting enzyme 2 (hACE2) under the cytokeratin 18 promoter (K18-hACE2). A new study indicates that this may not be a faithful model of human lethal infection with SARS-CoV-2.

18 Jan 2021

Study: NTRK fusions are far more frequently seen in pediatric tumors

In a large study of pediatric cancer patients, researchers from Children's Hospital of Philadelphia have analyzed the frequency, fusion partners, and clinical outcome of neurotrophic tyrosine receptor kinase (NTRK) fusions, which are clinical biomarkers that identify patients suitable for treatment with FDA-approved TRK inhibitors.

16 Jan 2021

Myelin‐specific T cells implicated in central nervous system disease in monkeys

Scientists have uncovered new clues implicating a type of herpes virus as the cause of a central nervous system disease in monkeys that's similar to multiple sclerosis in people.

15 Jan 2021

Novel compound appears to protect myelin and nerve fibers

A compound developed at Oregon Health & Science University appears to protect nerve fibers and the fatty sheath, called myelin, that covers nerve cells in the brain and spinal cord.

13 Jan 2021

Researchers identify link between ALS and accumulation of DNA-RNA hybrids in the genome

Researchers from the University of Seville and the University of Pavia have identified a link between Amyotrophic Lateral Sclerosis (ALS) and the accumulation of DNA-RNA hybrids in the genome.

13 Jan 2021

Study shows how neurons can become a target of SARS-CoV-2 infection

Using both mouse and human brain tissue, researchers at Yale School of Medicine have discovered that SARS-CoV-2 can directly infect the central nervous system and have begun to unravel some of the virus's effects on brain cells.

13 Jan 2021

ADC histogram analysis can predict tumor proliferation, survival in immunocompetent patients with PCNSL

The cover for issue 45 of Oncotarget features Figure 3, "Representative images of whole tumor volume segmentation of the co-registered T1 post-contrast sequence and apparent diffusion coefficient (ADC) map, yielding the corresponding ADC histogram distribution utilized for data analysis," recently published in "Diffusion-weighted MR imaging histogram analysis in HIV positive and negative patients with primary central nervous system lymphoma as a predictor of outcome and tumor proliferation" by Khan, et al.

12 Jan 2021

Researchers identify the missing link between intestinal disease and brain injury in premature infants

Physicians have long known that necrotizing enterocolitis (NEC), a potentially lethal inflammatory condition that destroys a premature infant's intestinal lining, is often connected to the development of severe brain injury in those infants who survive.

6 Jan 2021

Vitamin D supplementation found to reduce COVID-19-related mortality, says study

Researchers have shown that prescribing vitamin D supplementation to COVID-19 patients seems to decrease the mortality rate, the severity of the disease, and serum levels of inflammatory markers.

6 Jan 2021

Central Nervous System News and Research

New treatment can improve the lives of patients with spinal cord injury

Neurological and psychiatric complications six months after COVID-19 recovery

Ebola survivors experienced a resurgence in antibody levels after recovery

Certain malaria parasites use a mechanism to cross the blood–brain barrier

Inflammation of the brain gray matter decreases nerve-cell activity in mouse model

FDA takes action on alcohol-based hand sanitizers from Mexico

Researchers find microbiome-controlled anti-inflammatory subsets of astrocytes

Negative childhood experience connected to relatively unfavorable living situation

How does SARS-CoV-2 infect brain cells?

International consortium investigates specific cell signaling process across range of human diseases

Magnetic nanoparticles guide neurite growth in dopaminergic cells

Can transgenic mice studies illuminate neurological complications associated with SARS-CoV-2 in humans?

Study: NTRK fusions are far more frequently seen in pediatric tumors

Myelin‐specific T cells implicated in central nervous system disease in monkeys

Novel compound appears to protect myelin and nerve fibers

Researchers identify link between ALS and accumulation of DNA-RNA hybrids in the genome

Study shows how neurons can become a target of SARS-CoV-2 infection

ADC histogram analysis can predict tumor proliferation, survival in immunocompetent patients with PCNSL

Researchers identify the missing link between intestinal disease and brain injury in premature infants

Vitamin D supplementation found to reduce COVID-19-related mortality, says study

Event guide: The 7th CNS Drug Delivery Summit eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

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