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Random variability may contribute to differences in gut microbe populations, study finds

Within the human digestive tract, there are trillions of bacteria, and these communities contain hundreds or even thousands of species. The makeup of those populations can vary greatly from one person to another, depending on factors such as diet, environmental exposure, and health history.

6 Mar 2017

Exercise-induced irisin could regulate bone metabolism by autocrine mechanisms

Two weeks of voluntary wheel running induces higher expression of irisin--a fat-burning hormone that is released during exercise--in bone tissue in mice.

3 Mar 2017

New software tool enables quick, easy deletion of DNA in living cells

Until recently, genomics was a "read-only" science, but scientists have developed a tool for quick and easy deletion of DNA in living cells.

3 Mar 2017

Scientists discover how misfolded proteins can damage cells’ energy-producing powerhouses

Working with yeast and human cells, researchers at Johns Hopkins say they have discovered an unexpected route for cells to eliminate protein clumps that may sometimes be the molecular equivalent of throwing too much or the wrong trash into the garbage disposal.

3 Mar 2017

Notch activity of cells in tumor microenvironment can influence cancer metastases, study shows

Blood vessels play a critical role in the growth and spread of cancer. The cells lining the inner wall of blood vessels (endothelial cells) and cancer cells are in close contact to each other and mutually influence each other.

3 Mar 2017

Doctoral student in biology investigating cause of hereditary neurodegenerative disease

Babita Adhikari Dhungel, doctoral student in biology from Nepal, is researching the cause of CLN8 disease, which is a form of neuronal ceroid lipofuscinoses.

3 Mar 2017

Unexpected discovery paves way for new insights in regulation of bacterial virulence

Chemists and molecular biologists have made an unexpected discovery in infection biology. The researchers can now show that two proteins that bind to one another slow down a chemical reaction central to the course of the disease in the bacteria Yersinia pseudotuberculosis.

3 Mar 2017

NovAliX's new laboratory to use cryo-TEM for facilitating small molecule and biologic drug discovery

A new contract research laboratory operated by France-based NovAliX will provide pharmaceutical companies with access to high-resolution cryo-transmission electron microscopy (cryo-TEM) by Thermo Fisher Scientific for facilitating small molecule and biologic drug discovery.

3 Mar 2017

Blocking protein found on surface of ovarian cancer cells could prevent metastasis, research suggests

Blocking a protein found on the surface of ovarian cancer cells could prevent or reduce the spread of the disease to other organs, according to new research at the University of Illinois at Chicago.

3 Mar 2017

Scientists propose rejuvenating bone marrow stem cell niche to boost immunity, fend off cancers

As people get older so do the hematopoietic stem cells (HSCs) that form their blood, creating an increased risk for compromised immunity and certain blood cancers. Now researchers are reporting in the scientific journal that the bone marrow niche where HSC's form also ages, contributing to the problem.

3 Mar 2017

Scientists reveal new ‘threshold theory’ of how Parkinson's disease spreads

The toxic protein behind Parkinson's disease may not spread like an infection from nerve cell to nerve, according to a new theory by Technion and Harvard University scientists.

2 Mar 2017

City of Hope researchers find how HER2-positive breast cancer patients develop brain metastases

Ninety percent of cancer deaths are from cancer spread. Breast cancer patients, for example, typically do not die because cancer returns in their breast, they die because it spreads to other parts of their body. The most dangerous of which is the brain.

2 Mar 2017

Innovative gene therapy allows complete remission of clinical signs of sickle cell disease

A team led by Pr. Marina Cavazzana conducted at Necker Children's Hospital, AP-HP and the Imagine Institute in October 2014 gene therapy in the context of a phase I clinical trial / II in a patient 13 years with severe sickle cell disease.

2 Mar 2017

Study provides insights into how cancer cells can evade FGFR inhibitors

A new study by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute has identified a mechanism by which cancer cells develop resistance to a class of drugs called fibroblast growth factor receptor (FGFR) inhibitors.

2 Mar 2017

New interactive tool helps consumers to effectively balance benefits, risks of eating seafood

FishChoice, a new online tool to help consumers and professionals efficiently and effectively balance the benefits and risks of eating seafood, has been launched by the EU-funded ECsafeSEAFOOD project at www.fishchoice.eu.

2 Mar 2017

Scientists use molecular bait strategy to capture and isolate cancer-prone protein

Scientists from the Center for Self-assembly and Complexity (CSC) successfully isolated a cancer-prone protein by fishing out the proteins using 'molecular bait'.

2 Mar 2017

Scientists reveal new mRNA method to deliver safe, cost-effective therapeutic antibodies

Using antibodies to treat disease has been one of the great success stories of early 21st-century medicine. Already five of the ten top-selling pharmaceuticals in the United States are antibody products. But antibodies are large, complex proteins that can be expensive to manufacture.

2 Mar 2017

Hydraulic forces aid to fill the heart's chambers with blood, research finds

Researchers at Karolinska Institutet and KTH Royal Institute of Technology in Sweden have contributed to a recent discovery that the heart is filled with the aid of hydraulic forces, the same as those involved in hydraulic brakes in cars.

2 Mar 2017

Advances in Optogenetics

Optogenetics is a way of introducing information into the brain using light, it targets specific cells or connections across the brain. It is fast, like brain signaling, and helps you communicate with neural circuitry in a language more similar to what is normally used within the brain.

From Pittcon 2 Mar 2017

Study establishes ENL protein as potential drug target for acute myeloid leukemia

Anyone who uses an employee badge to enter a building may understand how a protein called ENL opens new possibilities for treating acute myeloid leukemia (AML), a fast-growing cancer of bone marrow and blood cells and the second most common type of leukemia in children and adults.

2 Mar 2017

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G Protein News and Research

Random variability may contribute to differences in gut microbe populations, study finds

Exercise-induced irisin could regulate bone metabolism by autocrine mechanisms

New software tool enables quick, easy deletion of DNA in living cells

Scientists discover how misfolded proteins can damage cells’ energy-producing powerhouses

Notch activity of cells in tumor microenvironment can influence cancer metastases, study shows

Doctoral student in biology investigating cause of hereditary neurodegenerative disease

Unexpected discovery paves way for new insights in regulation of bacterial virulence

NovAliX's new laboratory to use cryo-TEM for facilitating small molecule and biologic drug discovery

Blocking protein found on surface of ovarian cancer cells could prevent metastasis, research suggests

Scientists propose rejuvenating bone marrow stem cell niche to boost immunity, fend off cancers

Scientists reveal new ‘threshold theory’ of how Parkinson's disease spreads

City of Hope researchers find how HER2-positive breast cancer patients develop brain metastases

Innovative gene therapy allows complete remission of clinical signs of sickle cell disease

Study provides insights into how cancer cells can evade FGFR inhibitors

New interactive tool helps consumers to effectively balance benefits, risks of eating seafood

Scientists use molecular bait strategy to capture and isolate cancer-prone protein

Scientists reveal new mRNA method to deliver safe, cost-effective therapeutic antibodies

Hydraulic forces aid to fill the heart's chambers with blood, research finds

Advances in Optogenetics

Study establishes ENL protein as potential drug target for acute myeloid leukemia

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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