Neurodegenerative Diseases News and Research

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Study finds evidence for increased activity of the brain’s immune system long before dementia onset

Long before the onset of dementia, there is evidence for increased activity of the brain's immune system. Researchers from DZNE and the University Hospital Bonn come to this conclusion based on a study of more than 1,000 older adults.

12 Jan 2022

Novel insights about dopamine can help find better drugs for Parkinson's patients

New findings provide a better understanding of how the synthesis of dopamine is regulated in the brain. It may shed new light on the mechanism behind diseases such as Parkinson's.

12 Jan 2022

Developing a 'fingerprint' test that could diagnose Alzheimer’s early

In this interview, we spoke to Dr. Cynthia McMurray about her latest research into Alzheimer's disease.

11 Jan 2022

JPND announces call for multinational research on understanding the mechanisms of non-pharmacological interventions

The EU Joint Programme - Neurodegenerative Disease Research (JPND) initiative has announced a joint transnational call for multinational research on understanding the mechanisms of non-pharmacological interventions.

10 Jan 2022

Physical activity may help boost synaptic functioning in older adults

When elderly people stay active, their brains have more of a class of proteins that enhances the connections between neurons to maintain healthy cognition, a UC San Francisco study has found.

7 Jan 2022

Model of neuromuscular junction could accelerate new treatments for neuromuscular diseases

The neuromuscular junction - where nerves and muscle fibers meet - is an essential synapse for muscle contraction and movement.

6 Jan 2022

Research provides new insights on the architecture of yeast nuclear pore complex

Nuclear pore complexes (NPCs) are massive multi-protein complexes that act as passageways for the transport of molecules into and out of the nucleus.

3 Jan 2022

Excessive intake of simple sugar in adolescents could be a risk factor of psychiatric disorders

There has been a remarkable increase in intake of simple sugar (sucrose, isomerized sugar (corn syrup)) from beverages and diets in modern society. The intake of simple sugars in adolescents in which mental disorders frequently occur is higher than any other generations.

28 Dec 2021

Single-patient pilot study shows the ability of antisense oligonucleotide to suppress mutant ALS gene

Using a short, synthetic chain of chemically modified nucleotides engineered in the RNA Therapeutics Institute at UMass Chan Medical School, Robert H. Brown Jr., DPhil, MD, Jonathan Watts, PhD, and colleagues have shown the ability to suppress mutant forms of an ALS gene known as C9ORF72 in a single-patient pilot study.

24 Dec 2021

New study shines light on how brain cells die in prion diseases

Prion diseases, such as Creutzfeldt-Jakob Disease (CJD), are fast-moving, fatal dementia syndromes associated with the formation of aggregates of the prion protein, PrP.

22 Dec 2021

Study: Common gene mutation for Parkinson's disease drives mislocalization of iron in the brain

A common gene mutation for Parkinson's disease drives mislocalization of iron in activated microglia, according to a new study publishing December 16th in the open-access journal PLOS Biology, by Mark Cookson of the National Institute on Aging and colleagues

17 Dec 2021

Dementia project receives critical new funding

Women's Brain Health Initiative, Canadian Institutes of Health Research, and Brain Canada are pleased to announce that Dr. Mario Masellis has been selected to receive funding as part of the European Union Joint Programme on Neurodegenerative Disease Research (JPND)'s initiative on linking pre-diagnosis disturbances of physiological systems to neurodegenerative diseases.

14 Dec 2021

New research identifies the cause of Alzheimer’s progression

In this interview, we spoke to Dr. Georg Meisl about his latest research that helped to identify the cause of Alzheimer’s progression.

13 Dec 2021

Researchers discover new mechanism behind the formation of membrane vesicles

Canadian and American researchers have discovered a new mechanism by which membrane vesicles are made. These self-contained nanoparticles trap proteins, RNA and other molecules from inside or outside of living cells as nutrients or regulate the numbers of cell surface hormone receptors, such as those for insulin, to control the sensitivity of cells to hormones.

10 Dec 2021

Higher intake of plant-based foods could help reduce the risk of cognitive decline due to aging

A diet rich in plant products reduces the risk of cognitive impairment and dementia in the elderly. This is the result of a study by the Biomarkers and Nutritional Food Metabolomics Research Group of the Faculty of Pharmacy and Food Sciences of the University of Barcelona and the CIBER on Frailty and Healthy Aging.

9 Dec 2021

Study reveals the role of intracellular receptor PQBP1 in response to Tau protein

Just as a home security system can alert a homeowner to the presence of an intruder, a protein called polyglutamine binding protein-1 (PQBP1) found in brain cells can alert the body to the presence of "intruding" viruses like human immunodeficiency virus (HIV).

9 Dec 2021

Neurodegenerative Diseases News and Research

Study finds evidence for increased activity of the brain’s immune system long before dementia onset

Novel insights about dopamine can help find better drugs for Parkinson's patients

Developing a 'fingerprint' test that could diagnose Alzheimer’s early

JPND announces call for multinational research on understanding the mechanisms of non-pharmacological interventions

Physical activity may help boost synaptic functioning in older adults

Model of neuromuscular junction could accelerate new treatments for neuromuscular diseases

Research provides new insights on the architecture of yeast nuclear pore complex

Excessive intake of simple sugar in adolescents could be a risk factor of psychiatric disorders

Single-patient pilot study shows the ability of antisense oligonucleotide to suppress mutant ALS gene

New study shines light on how brain cells die in prion diseases

Study: Common gene mutation for Parkinson's disease drives mislocalization of iron in the brain

Dementia project receives critical new funding

New research identifies the cause of Alzheimer’s progression

Researchers discover new mechanism behind the formation of membrane vesicles

Higher intake of plant-based foods could help reduce the risk of cognitive decline due to aging

Study reveals the role of intracellular receptor PQBP1 in response to Tau protein

Scientists determine structure of the molecule associated with ALS for the first time

Researchers uncover the journey of microglia in developing zebrafish

‘Moving molecule’ therapy for severe spinal cord injury

Researchers use gene-editing to create single sex mice litters

eBook: Using iPSCs models for human disease research and drug discovery eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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