Neutrophils News and Research

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Gender differences and skin cancer

Inherent gender differences – instead of more sun exposure – may be one reason why men are three times more likely than women to develop certain kinds of skin cancer, say researchers at Ohio State University Medical Center.

2 Apr 2007

Effect of gender on the development of UVB-induced skin cancers

Inherent gender differences "instead of more sun exposure" may be one reason why men are three times more likely than women to develop certain kinds of skin cancer, say researchers at Ohio State University Medical Center.

2 Apr 2007

Dipeptidyl peptidase I critical for early growth of abdominal aortic aneurysms

Surgery is the only treatment for an abdominal aortic aneurysm, a weak spot in the body's main artery that dilates dangerously over time.

13 Feb 2007

Lung neutrophils produce histamine in significant quantities

In a surprise finding, scientists have discovered that histamine, the inflammatory compound released during allergic reactions that causes runny nose, watery eyes, and wheezing, can be produced in large amounts in the lung by neutrophils, the white blood cells that are the major component of pus.

14 Jan 2007

Why organs fail following massive trauma

Massive trauma, say from a sabertooth tiger attack, meant immediate death for the primitive human.

17 Oct 2006

New hope for patients with lung and joint disease

People who suffer from inflammatory conditions such as chronic diseases of the lung, joints and other organs could benefit from a new discovery by scientists at the University of Edinburgh.

4 Sep 2006

How does the immune system isolate and destroy intruders?

Dendritic cells are the body's "watchdogs". They recognize and then degrade pathogens, isolating characteristic fragments that are recognized by the immune system thus triggering targeted responses.

25 Jul 2006

Aggressive cancer treated successfully in mice

White blood cells from a strain of cancer-resistant mice cured advanced cancers in ordinary laboratory mice, researchers at Wake Forest University School of Medicine reported.

9 May 2006

Lipoxin A4 regulates bronchial epithelial cell responses to acid injury

Doctors are gaining new leverage in the fight against lung injury caused by acid reflux. The paper by Bonnans et al., "Lipoxin A4 regulates bronchial epithelial cell responses to acid injury," appears in the April issue of The American Journal of Pathology and is accompanied by a commentary.

3 May 2006

New finding provides researchers with renewable source for macrophages and neutrophils

A new approach to generating large quantities of two types of white blood cells that are critical for destroying invading bacteria, viruses and other pathogens in humans has been developed by researchers at the University of California, San Diego (UCSD) School of Medicine.

19 Apr 2006

Viagra could cure Crohn's disease

Crohn's disease is a chronic inflammatory bowel disorder which causes ulcerations in the gut and can make digesting food painful.

27 Feb 2006

Research points to a novel approach to treating serious Strep infections

Researchers at the University of California, San Diego (UCSD) School of Medicine have discovered that so-called flesh-eating "Strep" bacteria use a specific enzyme to break free of the body's immune system, a finding which could potentially lead to new treatments for serious infections in human patients.

24 Feb 2006

New molecular target for potential drugs to treat acute respiratory distress syndrome

Researchers at the University of Virginia Health System have identified a molecular target, or receptor, for potential drugs to treat acute respiratory distress syndrome (ARDS), a sudden and life-threatening failure of the lung.

23 Feb 2006

Scientists discover why lung, but not skin, anthrax infections are lethal

Scientists from the Max Planck Institute for Infection Biology in Berlin discovered why lung, but not skin, anthrax infections are lethal. As reported in the newest issue of PloS Pathogen (November 2005) Neutrophils, a form of white blood cells, play a key role in anthrax infections.

13 Nov 2005

Researchers uncover how the inhaled form of anthrax disarms bacteria-fighting white blood cells before they can fend off the disease

The lethal toxin in anthrax paralyzes neutrophils, the white blood cells that act as the body's first defense against infection, by impairing how they build tiny filaments that allow them to crawl throughout the body and eat invading bacteria.

6 Sep 2005

Two studies reveal how plague disables immune system

Two studies by researchers at the University of Chicago show how the bacteria that cause the plague manage to outsmart the immune system and how, by slightly altering one of the microbe's tools, the researchers produced what may be the first safe and effective vaccine.

1 Aug 2005

New way to fight antibiotic-resistant Staphylococcus infections

Researchers at the University of California, San Diego School of Medicine and Children’s Hospital and Health Center, San Diego have discovered that "Staph" bacteria use a protective golden armor to ward off the immune system, a finding with the potential to lead to new treatments for serious infections now increasingly resistant to standard antibiotics.

19 Jul 2005

White blood cell called a neutrophil appears to be crucial to abdominal aortic aneurysm formation

Each year, 200,000 Americans find out that the largest blood vessel in their body, the aorta, may burst open at any time. About 20,000 die suddenly from such a rupture. And another 36,000 have surgery to repair or replace the swelling section of aorta before time runs out.

13 Jul 2005

Bling Bling bacteria more dangerous!

Researchers in the U.S. have uncovered the interesting fact that gold-colored bacteria appear to cause more disease than colorless strains.

12 Jul 2005

Molecules that give certain bugs their color also help them resist attack by immune cells called neutrophils

A new study in the July 18 issue of The Journal of Experimental Medicine shows that gold-colored bacteria are more harmful than their unpigmented relatives.

11 Jul 2005