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Study reinforces the link between microglia and some cases of brain disease

Certain subtle differences in DNA sequences are known to raise the chances a person may develop Alzheimer's or Parkinson's disease.

6 Jan 2022

New study links anxiety and PTSD to increased myelin in brain's gray matter

A recent study links anxiety behavior in rats, as well as post traumatic stress disorder (PTSD) in military veterans, to increased myelin - a substance that expedites communication between neurons - in areas of the brain associated with emotions and memory.

6 Jan 2022

A new paradigm is needed: Top experts question the value of advance care planning

For decades, Americans have been urged to fill out documents specifying their end-of-life wishes before becoming terminally ill — living wills, do-not-resuscitate orders, and other written materials expressing treatment preferences.

6 Jan 2022

As covid hits nursing homes’ finances, town residents fight to save Alzheimer’s facility

Marvin Querry, 86, was on his tractor, planting rye on his 770-acre western Missouri farm, when the call came in early November.

4 Jan 2022

Promoting exercise as basic need for managing the physical and cognitive symptoms of MS

Citing recent evidence, experts in rehabilitation research advocate for integrating exercise into the care plans of persons with multiple sclerosis. The central role of the neurologist in clinical care offers an opportunity for this provider to promote exercise as fundamental for managing the physical and cognitive symptoms of MS.

30 Dec 2021

AAN issues new guideline on oral and topical treatments for painful diabetic neuropathy

Diabetic neuropathy refers to nerve damage due to diabetes and it may lead to pain and numbness, most often in the hands and feet. To help neurologists and other doctors determine the best treatment for people with diabetic neuropathy, the American Academy of Neurology (AAN) has issued a guideline on oral and topical treatments for painful diabetic neuropathy.

28 Dec 2021

Single-patient pilot study shows the ability of antisense oligonucleotide to suppress mutant ALS gene

Using a short, synthetic chain of chemically modified nucleotides engineered in the RNA Therapeutics Institute at UMass Chan Medical School, Robert H. Brown Jr., DPhil, MD, Jonathan Watts, PhD, and colleagues have shown the ability to suppress mutant forms of an ALS gene known as C9ORF72 in a single-patient pilot study.

24 Dec 2021

Blocking function of a blood-clotting protein may help prevent or treat periodontal disease

Blocking function of a blood-clotting protein prevented bone loss from periodontal (gum) disease in mice, according to research led by scientists at the National Institute of Dental and Craniofacial Research, part of the National Institutes of Health.

23 Dec 2021

T-cell response to Omicron after an mRNA COVID vaccine booster

In a recent prospective observational study posted to the medRxiv* preprint server, researchers determined Omicron variant-associated T cell responses before and after a third dose of messenger ribonucleic acid (mRNA) vaccination against coronavirus disease (COVID-19) in anti-CD20-treated multiple sclerosis (MS) patients.

22 Dec 2021

Study reveals how gut bacteria can impact the course of neurological diseases

A New York-based, multi-institutional research team has found high levels of three toxic metabolites produced by gut bacteria in the cerebrospinal fluid and plasma samples of multiple sclerosis (MS) patients.

21 Dec 2021

Study analyzes the role of circular RNA in ALS pathology

Amyotrophic lateral sclerosis, known as ALS, is a neurodegenerative disorder which affects motor neurons. These are the neuronal cells responsible for muscle innervation, whose degenerations leads to progressive paralysis culminating with motor and respiratory failure.

21 Dec 2021

A new approach for drugs to be more effective against inflammatory bowel disease

Biomedical scientists at the University of California, Riverside, propose a way for drugs to be more effective against inflammatory bowel disease, or IBD, in which the intestine undergoes inflammation.

18 Dec 2021

Study examines the effects of methylphenidate on mental fatigue in multiple sclerosis patients

A team of researchers at Kessler Foundation studied the effects of methylphenidate on mental fatigue in individuals with multiple sclerosis (MS). This is the first study to examine the psychostimulant's effects on 'state' vs 'trait' mental fatigue in MS.

18 Dec 2021

Sclerosis News and Research

Study reinforces the link between microglia and some cases of brain disease

New study links anxiety and PTSD to increased myelin in brain's gray matter

A new paradigm is needed: Top experts question the value of advance care planning

As covid hits nursing homes’ finances, town residents fight to save Alzheimer’s facility

Promoting exercise as basic need for managing the physical and cognitive symptoms of MS

AAN issues new guideline on oral and topical treatments for painful diabetic neuropathy

Single-patient pilot study shows the ability of antisense oligonucleotide to suppress mutant ALS gene

Blocking function of a blood-clotting protein may help prevent or treat periodontal disease

T-cell response to Omicron after an mRNA COVID vaccine booster

Study reveals how gut bacteria can impact the course of neurological diseases

Study analyzes the role of circular RNA in ALS pathology

A new approach for drugs to be more effective against inflammatory bowel disease

Study examines the effects of methylphenidate on mental fatigue in multiple sclerosis patients

Cannabinoid medicines have enormous therapeutic potential but reliable studies still lacking

Ophthalmology professor receives $75,000 grant to support international collaborations on eye research

New prototype enables people with severely impaired motor skills to communicate with others

Researchers discover why people with asthma have lower brain tumor risk

Scientists determine structure of the molecule associated with ALS for the first time

Systemic sclerosis more common among Black children than previously thought

Targeting the brain should be the focus of ALS therapy, not just spinal cord

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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