Spike Protein News and Research

RSS

Comparing effectiveness of virus and patients-centered strategies to reduce COVID-19 mortality

Researchers from Sorbonne Université have been reviewing papers exploring different anti-COVID-19 drugs.

19 Nov 2021

A nasal COVID vaccine using a weakened influenza vector

The authors of a new study, published on the bioRxiv* preprint server, constructed a COVID-19 nasal vaccine candidate by inserting a gene encoding the receptor-binding domain (RBD) of the spike protein of SARS-CoV-2, named CA4-dNS1-nCoV-RBD (dNS1-RBD) in a live attenuated influenza virus (LAIV) vector.

18 Nov 2021

SARS-CoV-2 infection and reinfection in farmed mink

A new study finds that farmed mink acquire SARS-CoV-2 infection, freely transmit it among themselves, and were reinfected, despite being seropositive.

18 Nov 2021

Structure of SARS-CoV-2 spike protein postfusion

A new study published in PNAS proposes a higher resolution in situ structure of the SARS-CoV-2 spike protein in its postfusion state.

18 Nov 2021

Study shows neutralizing capacity of monoclonal antibodies against SARS-CoV-2 variants of concern

Canadian public health researchers recently published a study in the journal Antiviral Research wherein they described generating a panel of murine hybridomas recognizing SARS-CoV-2 spike protein or nucleoprotein, capable of neutralizing the SARS-CoV-2 variants of concern, proving their therapeutic potential.

17 Nov 2021

P681H mutation helps SARS-CoV-2 VOCs replicate faster and resist innate immunity

In the current study, researchers compare the IFITM sensitivities of major SARS-CoV-2 VOCs.

17 Nov 2021

Interactions between SARS-CoV-2 S protein and ACE2 receptor using fluorescence correlation spectroscopy

Researchers used advanced two-color fluorescence cross-correlation spectroscopy to demonstrate the interaction between human ACE2 and the S1 subunit of SARS-CoV-2 and SARS-CoV.

17 Nov 2021

What genes affect the COVID-19 gender imbalance?

Many studies have established that coronavirus disease 2019 (COVID-19) is more infective in men than women, and men are more at risk of severe disease. While some have suggested that behavioral differences could explain increased transmission to men, this does not explain the more morbid prognosis.

16 Nov 2021

How effective is the COMIRNATY BNT162b2 vaccine against the SARS-CoV-2 Lambda variant?

Now, researchers from Public Health Services Israel have been investigating a new variant called Lambda to see if it qualifies as a variant of concern. Their research is published in the journal Eurosurveillance.

16 Nov 2021

Study: Covid-19 vaccine-elicited immune cells persist six months after vaccination

A recent study by Johns Hopkins Medicine researchers provides evidence that CD4+ T lymphocytes — immune system cells also known as helper T cells — produced by people who received either of the two available messenger RNA (mRNA) vaccines for COVID-19 persist six months after vaccination at only slightly reduced levels from two weeks after vaccination and are at significantly higher levels than for those who are unvaccinated.

16 Nov 2021

Discovery of new receptor that interacts with SARS-CoV-2 spike, suppresses infection

Researchers recently conducted a study to identify host factors affecting cellular interactions of the SARS-CoV-2 spike protein.

16 Nov 2021

Broad neutralization capability of potent nanobody against SARS-CoV-2 variants

A new study has described the molecular basis of the neutralization potency and breadth of nanobodies.

16 Nov 2021

Thrombosis with thrombocytopenia syndrome rare but serious adverse event associated with Ad26.COV2.S vaccination

A recent study conducted in the United States has revealed that thrombosis with thrombocytopenia syndrome following adenoviral vector-based coronavirus disease 2019 (COVID-19) vaccination is a rare event.

16 Nov 2021

Deficient spike-specific T cell responses and inability to neutralize SARS-CoV-2 variants 12 month post-infection

Researchers conducted a comprehensive, longitudinal, long-term immune study, including functional assays to assess immune fitness against antigenically different VoC. The study is currently available on the preprint server medRxiv* while awaiting peer review.

15 Nov 2021

Spike Protein News and Research

Comparing effectiveness of virus and patients-centered strategies to reduce COVID-19 mortality

A nasal COVID vaccine using a weakened influenza vector

SARS-CoV-2 infection and reinfection in farmed mink

Structure of SARS-CoV-2 spike protein postfusion

Study shows neutralizing capacity of monoclonal antibodies against SARS-CoV-2 variants of concern

P681H mutation helps SARS-CoV-2 VOCs replicate faster and resist innate immunity

Interactions between SARS-CoV-2 S protein and ACE2 receptor using fluorescence correlation spectroscopy

What genes affect the COVID-19 gender imbalance?

How effective is the COMIRNATY BNT162b2 vaccine against the SARS-CoV-2 Lambda variant?

Study: Covid-19 vaccine-elicited immune cells persist six months after vaccination

Discovery of new receptor that interacts with SARS-CoV-2 spike, suppresses infection

Broad neutralization capability of potent nanobody against SARS-CoV-2 variants

Thrombosis with thrombocytopenia syndrome rare but serious adverse event associated with Ad26.COV2.S vaccination

Deficient spike-specific T cell responses and inability to neutralize SARS-CoV-2 variants 12 month post-infection

Could drugs derived from microalgae be effective against COVID-19?

Vaccination protects against COVID-19 related hospitalization in patients with and without comorbidity

Detection of a coronavirus similar to SARS-CoV-2 in Cambodian bats

Can COVID-19 vaccination lead to neurological complications?

Increased risk of breakthrough SARS-CoV-2 infection with ChAdOx1 compared to BNT162b2 vaccine

Partial resistance to neutralizing antibodies and enhanced transmissibility of SARS-CoV-2 Delta variant

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News