Statin News and Research

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Statins are drugs used to lower cholesterol. Your body needs some cholesterol to work properly. But if you have too much in your blood, it can stick to the walls of your arteries, narrowing or even blocking them.

Pravastatin is highly effective in lowering the risk of heart attack

The cholesterol-lowering drug pravastatin is highly effective in lowering the risk of heart attack and other cardiovascular events in patients with diabetes and chronic kidney disease (CKD), reports a study in the December Journal of the American Society of Nephrology.

27 Oct 2005

Cholesterol levels and use of statins are not associated with breast cancer risk

Although some evidence suggests that statins (the most commonly used type of lipid-lowering drugs) may inhibit tumor development and may work in combination with chemotherapy drugs against cancer, studies on the association between the use of statins and breast cancer have had conflicting results

25 Oct 2005

New glaucoma risk calculator

High eye pressure is the leading risk factor for glaucoma, and is the only modifiable one. If glaucoma is untreated, vision loss may continue, leading to blindness in some individuals.

17 Oct 2005

Very low LDL cholesterol levels appear to be safe for heart patients on statin therapies

"There was no apparent safety concern for patients whose resultant LDL on intensive therapy was lower than current guidelines. There was a trend toward improved clinical outcomes in the lowest LDL groups," said Stephen D. Wiviott, M.D., from Brigham and Women's Hospital in Boston, Massachusetts.

11 Oct 2005

Cholesterol levels among older adults has declined significantly

The total cholesterol level among older adults has declined significantly, while there has been little change among younger adults, according to a study in the October 12 issue of JAMA: The Journal of the American Medical Association.

11 Oct 2005

Actos reduces the combined risk of non-fatal heart attacks, strokes in patients with type-2 diabetes

A study published in The Lancet shows that Takeda's Actos (pioglitazone HCl), an oral glucose lowering medication, significantly reduces the combined risk of non-fatal heart attacks, strokes and deaths by an additional 16% on top of standard medication

10 Oct 2005

Quality-improvement improves mortality in hospital

Heart attack death rates dropped significantly at hospitals that participated in a quality-improvement process that increased the use of evidence-based therapies, according to a new study in the Oct. 4, 2005, issue of the Journal of the American College of Cardiology.

28 Sep 2005

Benefits of statin therapy identified

The greater the reduction in LDL (lower-density lipoprotein) cholesterol achieved by statin therapy the greater the reduction in incidence of major coronary events, coronary revascularisation and stroke, concludes a meta-analysis published online today by The Lancet.

27 Sep 2005

$Statin use associated with a 36 percent reduction in risk of fracture$

Statin use associated with a 36 percent reduction in risk of fracture

In a large study of elderly, predominately male veterans, statin use was associated with a 36 percent reduction in risk of fracture when compared with no lipid-lowering therapy, according to a study in the Archives of Internal Medicine

26 Sep 2005

HDL cholesterol helps prevent blocked arteries and heart attack

Cardiology experts at Johns Hopkins have issued interim guidelines for physicians on how best to treat low levels of HDL cholesterol, the so-called good cholesterol, which helps keep arteries clear from the buildup of LDL cholesterol, the so-called bad cholesterol.

22 Sep 2005

Human fat cells produce a protein that is linked to both inflammation and an increased risk of heart disease and stroke

Researchers at The University of Texas M. D. Anderson Cancer Center and The University of Texas Health Science Center at Houston have found that human fat cells produce a protein that is linked to both inflammation and an increased risk of heart disease and stroke.

19 Sep 2005

Sports and exercise - in addition to preventing obesity and diabetes - directly improve vascular function and reduce atherosclerosis

When asked about his personal recipe for old age, Winston Churchill used to answer: "First of all: No sports." While being a visionary figure in world politics researchers in cardiovascular exercise science today would unanimously reply to his medical hypothesis: "Sorry, you are wrong."

5 Sep 2005

Nurse-led multidisciplinary programme can help coronary patients and their families to reduce their risk of major cardiovascular disease

Early results from the EuroAction hospital project, announced today at the European Society of Cardiology, demonstrate how a nurse-led multidisciplinary programme, organised in busy general hospitals, can help coronary patients and their families to reduce their risk of major cardiovascular disease (CVD).

5 Sep 2005

New blood pressure-lowering drugs reduce stroke risk by 50%

According to researchers the new types of blood pressure-lowering drugs are more effective in preventing strokes and heart attacks and save even more lives.

5 Sep 2005

Statins reduce heart attack deaths by 50%

According to a U.S. study, giving a heart attack patient a statin drug as soon as possible reduces the chance he or she will die by 50 percent.

30 Aug 2005

Early statin therapy may be essential for reducing mortality and other complications in heart attack victims

In the largest clinical study of its kind, UCLA researchers found that early treatment with a statin drug within 24 hours of having a heart attack reduced in-hospital mortality rates by over 50 percent.

29 Aug 2005

FDA Approves Aceon to reduce risk of cardiovascular mortality in patients with stable coronary artery disease

Solvay Pharmaceuticals and CV Therapeutics have announced that the U.S. Food and Drug Administration (FDA) has approved Aceon (perindopril erbumine) Tablets for the treatment of patients with stable coronary artery disease to reduce the risk of cardiovascular mortality or non-fatal myocardial infarction (MI).

24 Aug 2005

Latest findings on aspirin resistance

Treatment failures occur with any drug and aspirin is no exception. Evidence is growing that some people will not respond to the anti-coagulant action of aspirin and the drug will not protect against cardiovascular events despite its regular intake.

9 Aug 2005

Eplerenone shows benefit for patients with damaged hearts

In the first thirty days following a heart attack, one in three deaths among patients with signs of heart failure may be preventable by early treatment with a drug called eplerenone (Inspra, Pfizer Ltd), according to new data published in the Journal of the American College of Cardiology (JACC).

26 Jul 2005

Pneumonia - another use for statins

Patients hospitalised because of pneumonia are at less risk of dying from the disease if they have been taking the widely used cholesterol-lowering drugs 'statins' before hospital admission.

25 Jul 2005

Statin News and Research

Further Reading

Pravastatin is highly effective in lowering the risk of heart attack

Cholesterol levels and use of statins are not associated with breast cancer risk

New glaucoma risk calculator

Very low LDL cholesterol levels appear to be safe for heart patients on statin therapies

Cholesterol levels among older adults has declined significantly

Actos reduces the combined risk of non-fatal heart attacks, strokes in patients with type-2 diabetes

Quality-improvement improves mortality in hospital

Benefits of statin therapy identified

Statin use associated with a 36 percent reduction in risk of fracture

HDL cholesterol helps prevent blocked arteries and heart attack

Human fat cells produce a protein that is linked to both inflammation and an increased risk of heart disease and stroke

Sports and exercise - in addition to preventing obesity and diabetes - directly improve vascular function and reduce atherosclerosis

Nurse-led multidisciplinary programme can help coronary patients and their families to reduce their risk of major cardiovascular disease

New blood pressure-lowering drugs reduce stroke risk by 50%

Statins reduce heart attack deaths by 50%

Early statin therapy may be essential for reducing mortality and other complications in heart attack victims

FDA Approves Aceon to reduce risk of cardiovascular mortality in patients with stable coronary artery disease

Latest findings on aspirin resistance

Eplerenone shows benefit for patients with damaged hearts

Pneumonia - another use for statins

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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