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The use of bacterial colonists as therapy carriers is gaining interest for treating cancer

Study describes the use of engineered commensal bacteria to increase antitumor immunity.

23 Jun 2023

Vegetarian diet linked to increased risk of varicose veins in men

Varicose veins (VVs) pose a significant medical burden, particularly among women. This study investigates the association between vegetarian and non-vegetarian diets and the risk of VVs in both genders.

20 Jun 2023

The contribution of transcription factor ROB1 to the pathophysiology of C. albicans-induced candidal infections

Researchers evaluated the function of the zinc finger transcription factor ROB1 and its two phenotypically distinct alleles in the pathogenesis of Candida albicans infections.

20 Jun 2023

Battle against RSV: Computational design paves way for new polyvalent vaccine

Research focuses on the design of a multi-epitope polyvalent vaccine against Human Respiratory Syncytial Virus (RSV), a leading cause of lower respiratory tract infections. The study utilizes computational methods and immunoinformatics tools to predict potential vaccine candidates and their interactions with Toll-like receptors (TLRs).

19 Jun 2023

New mapping by Human Brain Project advances the understanding of neuroreceptor organization

A key challenge in neuroscience is to understand how the brain can adapt to a changing world, even with a relatively static anatomy.

19 Jun 2023

ACROBiosystems Aneuro Partners with Diagnostic Biochips to Accelerate Neuroscience Drug Discovery

ACROBiosystems, through ACRO Certify and under its Aneuro brand, recently announced the launch of in vivo electrophysiology solutions for neuroscience research with Diagnostic Biochips.

From ACROBiosystems 19 Jun 2023

Study provides a promising strategy for the treatment of neuroblastoma

Announcing a new publication for Acta Materia Medica journal. Neuroblastoma (NB) is a common solid tumor in children and infants, the formation and regression of which is closely linked to the tumor-host immune relationship.

19 Jun 2023

Neurodevelopmental disruptions could pave the way for Alzheimer's disease

In the cerebral cortex, neurogenesis – the formation of neural cells from stem cells – begins in the fetus from 5 weeks gestation and is almost complete by 28 weeks.

16 Jun 2023

Research explores complex relationship between cholesterol and breast cancer risk

Research explores the complex relationship between cholesterol and breast cancer risk, with some studies suggesting an increased risk with elevated cholesterol levels while others find an inverse association.

15 Jun 2023

Study reports outbreak of C. vulturna in a hospital in China

Researchers reported an increase in Candida vulturna infections among residents of China between 2019 and 2022.

15 Jun 2023

Breast cancer drug development work moves forward with support from STTR grant

Triple negative breast cancer is an aggressive subtype of breast cancer with worse survival outcomes than most.

14 Jun 2023

Connecting the inflammatory dots: Obesity, depression, and Alzheimer's linked by neuroinflammation

Obesity-induced neuroinflammation significantly contributes to the pathophysiology of depression and Alzheimer's disease. Targeting midlife stage for intervention is crucial to potentially prevent Alzheimer's pathology.

13 Jun 2023

Breaking barriers: hydrogel reservoir unleashes the potential of HSV-1 virotherapy in cancer

Researchers evaluated the therapeutic efficacy of Navoximod.

13 Jun 2023

Analyzing the role of LP-284 Hodgkin's lymphoma models and in DNA damage repair

A new research paper was published in Oncotarget's Volume 14 on June 12, 2023, entitled, "LP-284, a small molecule acylfulvene, exerts potent antitumor activity in preclinical non-Hodgkin's lymphoma models and in cells deficient in DNA damage repair."

13 Jun 2023

Antiretroviral treatment efficiently suppresses penile HIV replication

Of the 38 million people worldwide living with HIV, approximately 700,000 are newly infected men, primarily via sexual transmission.

12 Jun 2023

Manipulating white blood cells to eliminate solid tumors

By silencing the molecular pathway that prevents macrophages from attacking our own cells, Penn Engineers have manipulated these white blood cells to eliminate solid tumors.

12 Jun 2023

Study raises new hopes for blood cancer patients with an incomplete response to CAR T cell therapy

The aim of immunotherapy strategies is to use cells in the patient's own immune system to destroy tumor cells. CAR T cell therapy is an immunotherapy that is effective in treating blood cancer.

12 Jun 2023

Study reveals how p62 bodies control redox-independent stress response

Cellular stress, or oxidative stress, occurs when there is a buildup of reactive oxygen species (ROS), which interferes with cellular mechanisms and can even cause damage to proteins, lipids, and DNA.

12 Jun 2023

Mechanistic insights into how the SARS-CoV-2 virus affects the nervous system, alters its function, and causes neuropathology

Study demonstrates that SARS-CoV-2 infection and viral fusogens cause glial and neuronal fusion.

9 Jun 2023

Axol Bioscience collaborates with StrataStem to deliver stem cell based ‘clinical trial in a dish’ for Alzheimer’s disease

Axol Bioscience Ltd. (Axol), a leading pluripotent stem cell technology provider for drug discovery has signed an exclusive agreement with StrataStem to access and commercialize its extensive collection of Alzheimer’s Disease (AD) patient samples.

From Axol Bioscience Ltd 7 Jun 2023

in vivo News and Research

The use of bacterial colonists as therapy carriers is gaining interest for treating cancer

Vegetarian diet linked to increased risk of varicose veins in men

The contribution of transcription factor ROB1 to the pathophysiology of C. albicans-induced candidal infections

Battle against RSV: Computational design paves way for new polyvalent vaccine

New mapping by Human Brain Project advances the understanding of neuroreceptor organization

ACROBiosystems Aneuro Partners with Diagnostic Biochips to Accelerate Neuroscience Drug Discovery

Study provides a promising strategy for the treatment of neuroblastoma

Neurodevelopmental disruptions could pave the way for Alzheimer's disease

Research explores complex relationship between cholesterol and breast cancer risk

Study reports outbreak of C. vulturna in a hospital in China

Breast cancer drug development work moves forward with support from STTR grant

Connecting the inflammatory dots: Obesity, depression, and Alzheimer's linked by neuroinflammation

Breaking barriers: hydrogel reservoir unleashes the potential of HSV-1 virotherapy in cancer

Analyzing the role of LP-284 Hodgkin's lymphoma models and in DNA damage repair

Antiretroviral treatment efficiently suppresses penile HIV replication

Manipulating white blood cells to eliminate solid tumors

Study raises new hopes for blood cancer patients with an incomplete response to CAR T cell therapy

Study reveals how p62 bodies control redox-independent stress response

Mechanistic insights into how the SARS-CoV-2 virus affects the nervous system, alters its function, and causes neuropathology

Axol Bioscience collaborates with StrataStem to deliver stem cell based ‘clinical trial in a dish’ for Alzheimer’s disease

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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