Coronavirus News and Research

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Direct structural link between SARS-CoV-2 and essential fatty acid

Now, a new study published on the preprint server bioRxiv in June 2020 reports the discovery of a novel free fatty acid (FFA) binding pocket on the SARS-CoV-2 virus that could explain in part the viral effects of hyperinflammation, immune modulation, and membrane structure.

21 Jun 2020

Balanced B and T cell response required to control SARS-CoV-2

A new study by researchers in the Netherlands and published on the preprint server bioRxiv in June 2020 describes the differences in T and B cell responses seen in patients with severe COVID-19.

21 Jun 2020

COVID-19 plasma therapy safe and improves survival, says large study

Researchers working on COVID-19 therapy with plasma from convalescent patients have found that it is safe and effective and improves the chances of survival among those who are severely ill. The new study titled, “Safety Update: COVID-19 Convalescent Plasma in 20,000 Hospitalized Patients,” is published as a preprint for the journal Mayo Clinic Proceedings.

20 Jun 2020

Italy’s sewage water shows SARS-CoV-2 present prior to reported outbreak in Wuhan

Italian researchers have found traces of the novel coronavirus SARS-CoV-2 in sewage wastewater that indicates that the virus may have been in circulation since December 2019. This controversial discovery shows that even before the first case was reported in Wuhan, China, in late December 2019, the virus had already arrived in northern Italy.

20 Jun 2020

Voice analysis by smartphone app detects lung congestion in heart failure patients

Voice analysis by a smartphone app identifies lung congestion in heart failure patients, allowing early intervention before their condition deteriorates.

19 Jun 2020

Researchers develop method to estimate time-dependent reproduction number

In times of Corona, everybody looks at the reproduction number. However, this important number is subject to uncertainties.

19 Jun 2020

Characterizing "re-positives" in recovered COVID-19 patients

The novel coronavirus pandemic has been spreading silently or explosively in almost every country of the world, causing almost half a million deaths and nearly 8.5 million reported cases in just six months. While much is known about the virus and the illness by now, far more remains unclear. One such is the prevalence and persistence of antiviral immunity following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

19 Jun 2020

Discovery of biomarkers that can influence COVID-19 severity

The novel coronavirus, now called the severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), is the causative agent of the dreaded coronavirus disease (COVID-19). It was first discovered in Wuhan City, China, back in late December 2019 and has since then spread throughout the globe.

19 Jun 2020

Human trials to commence using SARS-CoV-2 antibodies from cow's blood

The coronavirus pandemic has sparked a sense of urgency as it actively spreads across the globe. The number of reported cases has now surpassed 8.46 million people, with a death toll of more than 453,000. Scientists and pharmaceutical companies are racing to develop an effective treatment and vaccine against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

19 Jun 2020

Nanosponges attract coronavirus away from lung cells, study shows

Imagine if scientists could stop the coronavirus infection in its tracks simply by diverting its attention away from living lung cells? A new therapeutic countermeasure, announced in a Nano Letters study by researchers from Boston University's National Emerging Infectious Diseases Laboratories and the University of California San Diego, appears to do just that in experiments that were carried out at the NEIDL in Boston.

18 Jun 2020

Blood types and COVID-19 risk confirmed

Blood type may play a pivotal role in driving disease severity among coronavirus disease (COVID-19) patients. Genetic analysis of COVID-19 patients has shown that people with blood type O seemed to be protected against severe disease. In contrast, those with blood type A may experience complications tied to the viral infection.

18 Jun 2020

Widespread testing could help stop the spread of COVID-19

The world is now in the grips of a historic pandemic. The death toll from the novel coronavirus has climbed to more than 117,000 in the United States and 448,000 around the world.

18 Jun 2020

Study examines the impact of urban density on spread of COVID-19

A new study suggests that denser places, assumed by many to be more conducive to the spread of the coronavirus that causes COVID-19, are not linked to higher infection rates.

18 Jun 2020

Crystal structure of SARS-CoV-2 protease-inhibitor in complex with a Chinese herb Shikonin

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus has been spreading rampantly over the whole world, infecting millions of people (over 8.45 million at last count), with over 452,000 deaths, as of June 19, 2020. It causes a broad spectrum of disease manifestations, from asymptomatic disease to severe or even fatal respiratory symptoms.

18 Jun 2020

Novel SARS-CoV-2 antibody cocktail impeccably mimics human antibody response

By using both humanized mice and convalescent patients, the researchers from the US and Singapore successfully generated non-competing and highly potent monoclonal antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein that could potentially be combined to form antibody cocktails. Their groundbreaking paper is published in the leading research journal Science.

18 Jun 2020

Throat gargling may be beneficial during the COVID-19 pandemic

Researchers from Chang Gung University College of Medicine, Taiwan, have suggested that throat gargling may have beneficial effects during the coronavirus disease 2019 (COVID-19) pandemic.

18 Jun 2020

First genome-wide CRISPR screen reveals genes that control SARS-CoV-2 infection

By performing a genome-wide CRISPR screen on the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), U.S. researchers identified novel proviral genes and pathways, and highlighted host genes that may regulate coronavirus disease (COVID-19) pathogenesis, as well as revealing potential targets for novel treatment approaches. Their findings are currently available on the bioRxiv* preprint server.

18 Jun 2020

COVID-19 pandemic affects sexual and reproductive health of young people

Social distancing and limited access to contraceptive and abortion care during the COVID-19 pandemic is affecting the sexual and reproductive health of adolescents and young adults according to a new study by researchers at Columbia University Mailman School of Public Health and Rutgers University.

18 Jun 2020

DFG establishes interdisciplinary commission to strengthen pandemic research

Against the background of the current coronavirus pandemic, the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) is to establish an interdisciplinary commission for pandemic research.

18 Jun 2020

Certain patients who receive hospital care for COVID-19 exhibit clear signs of brain injury

Certain patients who receive hospital care for coronavirus infection (COVID-19) exhibit clinical and neurochemical signs of brain injury, a University of Gothenburg study shows. In even moderate COVID-19 cases, finding and measuring a blood-based biomarker for brain damage proved to be possible.

18 Jun 2020