Hormone News and Research

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A hormone is a chemical released by one or more cells that affects cells in other parts of the organism. Only a small amount of hormone is required to alter cell metabolism. It is essentially a chemical messenger that transports a signal from one cell to another.

Researchers shed new light on the development of cancers, particularly breast and prostate cancer

Researchers at Brown Medical School and Rhode Island Hospital have shed new light on the activation of a protein key to the development of cancers, particularly breast and prostate cancer, the most commonly diagnosed cancers in the United States.

13 Jan 2005

Euro funding for diabetes and exercise research

Researchers at The University of Nottingham are among a network of European scientists who have been awarded €12.7 million (around £8.7 million) for a study into the relationship between lack of exercise and the development of diabetes — and the health benefits of regular exercise in its prevention and cure.

12 Jan 2005

Corticosteroids can be beneficial in the treatment of Duchenne muscular dystrophy

Corticosteroids can be beneficial in the treatment of Duchenne muscular dystrophy and can be offered as a treatment option, according to the American Academy of Neurology and the Child Neurology Society in a new practice guideline published in the January 11 issue of Neurology, the scientific journal of the American Academy of Neurology.

10 Jan 2005

Serono announces the availability of Saizen for adult growth hormone deficiency

Serono announced today the availability of Saizen [somatropin (rDNA origin) for injection] for use in the treatment of patients with adult growth hormone deficiency (AGHD), following its FDA approval.

10 Jan 2005

Hormone replacement therapy associated with increased risk of stroke

Hormone replacement therapy (HRT) is associated with an increased risk of stroke, especially ischaemic stroke, finds a review of trials published on bmj.com today.

7 Jan 2005

Direct modulation of progesterone signaling appears to influence ovarian cancer risk

A woman's risk of ovarian cancer rises significantly if she carries either of two previously unexamined variations in the gene that codes for the progesterone receptor, according to a team of researchers led by scientists from the Keck School of Medicine of the University of Southern California.

5 Jan 2005

Exposure to the chemical BPA (Bisphenol A) stimulates prostate cancer cell growth

An estrogen-like chemical commonly used to synthesize plastic food containers has been shown to encourage the growth of a specific category of prostate cancer cell, potentially affecting the treatment efficacy for a subset of prostate cancers.

4 Jan 2005

Study shows women with invasive lobular carcinoma may not need chemotherapy before surgery

Women with a rare type of advanced breast cancer who do not benefit from primary (pre-surgical) chemotherapy still have been found to do better in the long run than patients with a more common advanced breast cancer who do respond to chemotherapy.

3 Jan 2005

Polycystic ovary syndrome (PCOS), the most common endocrine disorder among reproductive-age women

The polycystic ovary syndrome (PCOS), the most common endocrine disorder among reproductive-age women, produces a wide variety of body changes with both physical and emotional implications for sufferers.

3 Jan 2005

Link between body-mass index and oral-contraceptive failure

Overweight and obese women who take oral contraceptives are 60 percent to 70 percent more likely to get pregnant while on the birth-control pill, respectively, than women of lower weight, according to new findings from Fred Hutchinson Cancer Research Center that will be published in the January issue of Obstetrics & Gynecology.

30 Dec 2004

Research animals experience severe stress response at slightest contact with researchers

Mice, rabbits, rats, beagles, geese, and other animals all show measurable physiological stress responses to routine laboratory procedures that have been up until now viewed as relatively benign.

28 Dec 2004

World Health Organization's new global report on iodine deficiency

The number of countries where iodine deficiency is a public health problem has halved over the past decade, says the World Health Organization (WHO) in a new global report on iodine status.

26 Dec 2004

Hirsute women most likely have androgen excess-related disorders, primarily polycystic ovary syndrome

Among women in their child-bearing years, even minimal amounts of unwanted hair in male-type patterns – especially in the presence of other subtle changes – may be a sign of a hormonal imbalance linked to a variety of serious side effects and medical conditions, according to the December 2004 issue of the American Journal of Obstetrics and Gynecology.

23 Dec 2004

Living alone, financial difficulties, excessive use of alcohol associated with the onset of depression among outpatients with heart failure

Living alone, financial difficulties, excessive use of alcohol and poor results on a heart failure questionnaire were associated with the onset of depression among outpatients with heart failure, according to a new study in the Dec. 21, 2004 issue of the Journal of the American College of Cardiology.

21 Dec 2004

Tercica files for patent infringement

Tercica announced today the filing of a suit for patent infringement in the High Court of Justice (Chancery Division Patents Court) in the United Kingdom against Insmed Incorporated of Glen Allen, Virginia and Avecia Limited of the United Kingdom.

20 Dec 2004

Obesity drug codenamed AOD9604 highly successful in trials

An Australian-owned obesity drug, developed by Melbourne-based biotechnology company Metabolic Pharmaceuticals Limited, is set to enter final human trials next year after successfully completing a Phase 2b human trial which proved that the drug induces weight loss and is very well tolerated with no evidence of the side effects commonly experienced with existing obesity drugs.

16 Dec 2004

Landmark studies that may change the treatment standards for breast cancer

The 27th Annual San Antonio Breast Cancer Symposium that took place December 8-11 included the presentation of several landmark studies that may change the treatment standards for breast cancer.

14 Dec 2004

Successful human trial of obesity drug that mimicks metabolic effects of growth hormone

The AOD9604 molecule is a small orally active peptide modelled on one section of the human growth hormone molecule. Growth hormone naturally occurs in the body and has profound stimulatory effects on fat metabolism, with levels of the hormone typically becoming suppressed in the obese state.

13 Dec 2004

New approach to genomic testing identifies women with low risk of breast cancer recurrence

An initial validation study presented by Exagen Diagnostics at the San Antonio Breast Cancer Symposium suggests it may soon be possible to distinguish good prognosis from poor prognosis in any newly diagnosed breast cancer patient based on DNA changes in the patient's tumor.

13 Dec 2004

Understanding what causes narcolepsy

Results of a preliminary study in this week’s issue of THE LANCET suggest a step forward in our understanding of the processes behind narcolepsy; there appears to be an underlying autoimmune process for people with a certain genetic profile. Future diagnostic testing of people with this profile should lead to substantial improvements in disease treatment.

13 Dec 2004

Hormone News and Research

Further Reading

Researchers shed new light on the development of cancers, particularly breast and prostate cancer

Euro funding for diabetes and exercise research

Corticosteroids can be beneficial in the treatment of Duchenne muscular dystrophy

Serono announces the availability of Saizen for adult growth hormone deficiency

Hormone replacement therapy associated with increased risk of stroke

Direct modulation of progesterone signaling appears to influence ovarian cancer risk

Exposure to the chemical BPA (Bisphenol A) stimulates prostate cancer cell growth

Study shows women with invasive lobular carcinoma may not need chemotherapy before surgery

Polycystic ovary syndrome (PCOS), the most common endocrine disorder among reproductive-age women

Link between body-mass index and oral-contraceptive failure

Research animals experience severe stress response at slightest contact with researchers

World Health Organization's new global report on iodine deficiency

Hirsute women most likely have androgen excess-related disorders, primarily polycystic ovary syndrome

Living alone, financial difficulties, excessive use of alcohol associated with the onset of depression among outpatients with heart failure

Tercica files for patent infringement

Obesity drug codenamed AOD9604 highly successful in trials

Landmark studies that may change the treatment standards for breast cancer

Successful human trial of obesity drug that mimicks metabolic effects of growth hormone

New approach to genomic testing identifies women with low risk of breast cancer recurrence

Understanding what causes narcolepsy

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