Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Mechanisms and strategies for antibody binding and escape in SARS-CoV-2

A new study investigated the mechanisms for binding and strategies to escape several hNAbs used by SARS-CoV-2 strains through molecular simulations.

10 Nov 2021

Ion channel mechanosensor plays a key role in regulating the speed of skin wound healing

PIEZO1, an ion channel mechanosensor found within cells, has been revealed to play a key role in regulating the speed of skin wound healing by researchers at the University of California, Irvine.

10 Nov 2021

Retinoid therapy improves vision in mice with Usher syndrome

Using data generated from patients and mice with genetic mutation for the disorder Usher syndrome, researchers from the University of Maryland School of Medicine, the National Institutes of Health's National Eye Institute, and National Institute on Deafness and Other Communication Disorders, documented the natural history of vision impairment in patients and identified the cell mechanism behind progressive vision loss.

9 Nov 2021

Researchers investigate how intestinal bacteria distribute metabolic products in membrane vesicles

Bacteria in the intestine pack a wide spectrum of their biomolecules into small capsules. These are transported via the bloodstream to various organs in the body and even absorbed and processed by nerve cells in the brain.

9 Nov 2021

Study reveals a previously unrecognized cause of vascular injury in type 2 diabetes

Altered function of the red blood cells leads to vascular damage in type 2 diabetes. Results from a new study in cells from patients with type 2 diabetes and mice show that this effect is caused by low levels of an important molecule in the red blood cells.

9 Nov 2021

Elusive white blood cells play a role in impaired T cell functions and counts in people with HIV

In a groundbreaking study of people living with HIV, University of Alberta researchers found that elusive white blood cells called neutrophils play a role in impaired T cell functions and counts, as well as the associated chronic inflammation that is common with the virus.

9 Nov 2021

New computer program can read any genome sequence and decipher its genetic code

Yekaterina "Kate" Shulgina was a first year student in the Graduate School of Arts and Sciences, looking for a short computational biology project so she could check the requirement off her program in systems biology. She wondered how genetic code, once thought to be universal, could evolve and change.

9 Nov 2021

HSS study provides insight into real-world medication use for treatment of psoriatic arthritis

Despite clear directives outlined in the updated guidelines published by the American College of Rheumatology/National Psoriasis Foundation (ACR/NPF) in 2018, there is limited data regarding medication use in real-world clinical practice and patient medication preferences for the treatment of psoriatic arthritis (PsA).

9 Nov 2021

A measles-vectored COVID-19 vaccine induces strong immunity in animal model

A new study explores the potential of MV-based vaccines targeting the S protein of SARS-CoV-2.

9 Nov 2021

COVID-19 and loss of sense of smell

A recent review examines the high susceptibility of the olfactory epithelium to SARS-CoV-2 infection.

9 Nov 2021

Psychiatric drug prevents some of the most serious complications of COVID-19, study finds

Leonard Imbula of the Healthy Mind Lab at Washington University School of Medicine in St. Louis holds a bottle of fluvoxamine, a psychiatric drug that has been shown, in a pair of studies conducted on two continents, to be an effective treatment for people sick with COVID-19.

9 Nov 2021

Targeting Shp2 in oncological treatments appears to worsen the disease

In recent years, much scientific effort and funding has focused on developing drugs that target an enzyme with the unwieldy name of Src homology 2-containing protein tyrosine phosphatase 2 or more briefly, Shp2.

9 Nov 2021

SARS-CoV-2 infection regulates protein arginylation

A new study explores the role of arginylation during SARS-CoV-2 infection.

9 Nov 2021

Scientists discover gene responsible for doubling the risk of respiratory failure from COVID-19

Scientists at Oxford University have identified the gene responsible for doubling the risk of respiratory failure from COVID-19.

9 Nov 2021

Multiplex network offers a systematic approach to study rare, uncharacterized diseases

Rare diseases are usually caused by a single genetic defect. Nevertheless, the search for the cause and the assessment of the effects is highly complex and difficult.

9 Nov 2021

The role of T follicular helper cells in the humoral immune response to SARS-CoV-2

The current analysis indicates that cTfh cells react to the spike antigen following vaccination are associated with anti-S protein neutralizing antibodies.

9 Nov 2021

Pregnant women’s humoral response is dependent on SARS-CoV-2 strain

The current study from Israel discusses the change in antibody response with the trimester of infection and the infecting variant.

9 Nov 2021

SARS-CoV-2 leaves long-term impact on olfactory neurocircuit

The current study looked at the impact of the virus on the CNS in the Syrian golden hamster, a useful animal model for COVID-19.

9 Nov 2021

Novel tetravalent antibodies for the ultrapotent and broad neutralization of SARS-CoV-2 variants

Researchers from the University of Toronto set out to create a new tetravalent antibody that could bind with enough potency that it could remain effective against VOCs.

9 Nov 2021

Enhanced neutralizing antibody and T-cell responses by DNA-based vaccine encoding SARS-CoV-2 spike protein

Researchers from VaxiGen have been investigating the potential for a DNA vaccine boost to VP vaccines against coronavirus disease 2019.

9 Nov 2021

Protein News and Research

Further Reading

Mechanisms and strategies for antibody binding and escape in SARS-CoV-2

Ion channel mechanosensor plays a key role in regulating the speed of skin wound healing

Retinoid therapy improves vision in mice with Usher syndrome

Researchers investigate how intestinal bacteria distribute metabolic products in membrane vesicles

Study reveals a previously unrecognized cause of vascular injury in type 2 diabetes

Elusive white blood cells play a role in impaired T cell functions and counts in people with HIV

New computer program can read any genome sequence and decipher its genetic code

HSS study provides insight into real-world medication use for treatment of psoriatic arthritis

A measles-vectored COVID-19 vaccine induces strong immunity in animal model

COVID-19 and loss of sense of smell

Psychiatric drug prevents some of the most serious complications of COVID-19, study finds

Targeting Shp2 in oncological treatments appears to worsen the disease

SARS-CoV-2 infection regulates protein arginylation

Scientists discover gene responsible for doubling the risk of respiratory failure from COVID-19

Multiplex network offers a systematic approach to study rare, uncharacterized diseases

The role of T follicular helper cells in the humoral immune response to SARS-CoV-2

Pregnant women’s humoral response is dependent on SARS-CoV-2 strain

SARS-CoV-2 leaves long-term impact on olfactory neurocircuit

Novel tetravalent antibodies for the ultrapotent and broad neutralization of SARS-CoV-2 variants

Enhanced neutralizing antibody and T-cell responses by DNA-based vaccine encoding SARS-CoV-2 spike protein

Ultimate guide to the essential tools for the characterization of proteins, polymers and nanoparticles eBook

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