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New computational approach creates spatial maps of single-cell data within tissues

A new computational approach developed by researchers at The University of Texas MD Anderson Cancer Center successfully combines data from parallel gene-expression profiling methods to create spatial maps of a given tissue at single-cell resolution.

21 Mar 2022

Trial reveals effectiveness of axi-cel as first-line treatment for high-risk lymphoma

Results from the ZUMA-12 trial led by researchers at The University of Texas MD Anderson Cancer Center showed that first-line treatment with axicabtagene ciloleucel (axi-cel), a chimeric antigen receptor (CAR) T cell therapy, achieved a high rate of complete response in patients with high-risk large B-cell lymphoma (LBCL).

21 Mar 2022

Intranasal delivery of pro-resolving lipid mediators arrests memory loss in experimental Alzheimer’s model

A research collaboration between scientists at LSU Health New Orleans and the Karolinska Institutet in Sweden has found that applying specialized pro-resolving lipid mediators intranasally arrested memory loss and brain degeneration in an experimental model of Alzheimer's Disease (AD).

21 Mar 2022

Oral drug that reverses immune aging effectively prevents death in COVID-19 mouse model

The immune system deteriorates with age, making COVID-19 particularly deadly in older people - but to date, no clinically available medication addresses this key risk factor.

21 Mar 2022

20% of childhood AML cases associated with rare genetic changes inherited through family bloodlines

It's a diagnosis you never want to hear: Acute Myeloid Leukemia (AML). These three words represent a devastating diagnosis of childhood cancer with dire consequences for many families.

21 Mar 2022

New test greatly simplifies the diagnosis of allergies

Although allergies are widespread, their diagnosis is complex and, depending on the type of allergy, the prospects of success with therapy are not always clear.

21 Mar 2022

TTUHSC secures $1.87 million grant to investigate the impact of vitamin A depletion on Alzheimer’s disease

Ongoing research suggests that an accumulation of toxic reactive oxygen species (ROS) in the area of the brain known as the hippocampal dentate gyrus may begin early on in patients with Alzheimer's disease.

21 Mar 2022

LJI study may open the door to new Parkinson's treatments and diagnostics

Scientists at La Jolla Institute for Immunology have found that people with Parkinson's disease have a clear "genetic signature" of the disease in their memory T cells.

21 Mar 2022

Study explores novel antiviral activity of PAD inhibitors against human beta-coronaviruses HCoV-OC43 and SARS-CoV-2

In a new study, researchers aimed to determine if peptidyl-arginine deiminases inhibitors may be used as a novel class of host-targeting antivirals against human coronaviruses.

21 Mar 2022

Glycogen synthase kinase-3 inhibitors found to attenuate COVID-19-associated cytokine storm

In a new study, researchers investigated whether the SARS-CoV-2 spike protein and its S2 subunit induced the expression of C–X–C motif chemokine 10, a subset of cytokine.

21 Mar 2022

Could sound waves help to regrow bones?

In this interview, we speak to Dr. Amy Gelmi and Professor Leslie Yeo about their new research that looked at using sound waves to regrow bones.

21 Mar 2022

Study aimed to identify the direct pathway that associates integrins with vascular dysregulation during SARS-CoV-2 infection

Researchers demonstrated the role of integrin signaling in vascular dysfunction associated with SARS-CoV-2 infection.

21 Mar 2022

The importance of the endosomal pathway for SARS-CoV-2 entry

Researchers demonstrated that combined inhibition of cell-surface-based and endosomal pathways completely blocked SARS-CoV-2 entry into mammalian cells.

21 Mar 2022

Sectra signs digital pathology contract with Erasmus MC

International medical imaging IT and cybersecurity company Sectra has signed a digital pathology contract with Erasmus University Medical Center (Erasmus MC) in the Netherlands.

21 Mar 2022

Biological timeline of COVID-19 immune recovery described in new research

In a recent study published on the bioRxiv* preprint server, a group of researchers from the University of California, San Francisco, looked at intra-patient immunological changes over time to see if there were any changes in immune responses associated with successful COVID-19 resolution.

21 Mar 2022

Study unveils several natural marine products as potential agents against SARS-CoV-2

A recent study, published in the Journal of Natural Products of the American Chemical Society and American Society of Pharmacognosy, highlighted three natural marine products as potent inhibitors of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – without any apparent toxic effects for human lung cells.

21 Mar 2022

B Cell News and Research

New computational approach creates spatial maps of single-cell data within tissues

Trial reveals effectiveness of axi-cel as first-line treatment for high-risk lymphoma

Intranasal delivery of pro-resolving lipid mediators arrests memory loss in experimental Alzheimer’s model

Oral drug that reverses immune aging effectively prevents death in COVID-19 mouse model

20% of childhood AML cases associated with rare genetic changes inherited through family bloodlines

New test greatly simplifies the diagnosis of allergies

TTUHSC secures $1.87 million grant to investigate the impact of vitamin A depletion on Alzheimer’s disease

LJI study may open the door to new Parkinson's treatments and diagnostics

Study explores novel antiviral activity of PAD inhibitors against human beta-coronaviruses HCoV-OC43 and SARS-CoV-2

Glycogen synthase kinase-3 inhibitors found to attenuate COVID-19-associated cytokine storm

Could sound waves help to regrow bones?

Study aimed to identify the direct pathway that associates integrins with vascular dysregulation during SARS-CoV-2 infection

The importance of the endosomal pathway for SARS-CoV-2 entry

Sectra signs digital pathology contract with Erasmus MC

Biological timeline of COVID-19 immune recovery described in new research

Study unveils several natural marine products as potential agents against SARS-CoV-2

Sex-specific differences in T-cell responses to COVID-19

Novel device uses tiny worms to detect lung cancer cells

Response to COVID-19 boosters in seronegative multiple sclerosis patients

How does the non-structural protein 1 affect COVID-19 pathogenicity?

Using single B cell screening to boost antibody discovery eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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