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New drug patent may help overcome problems associated with MDR-TB

A chemist based at the University of Copenhagen has just taken out a patent for a drug that can make previously multidrug-resistant bacteria once again responsive to antibiotics.

18 Feb 2014

UT Southwestern receives grant to establish Center for Patient-Centered Outcomes Research

UT Southwestern Medical Center has been funded to establish a Center for Patient-Centered Outcomes Research that supports and conducts high-quality research comparing the outcomes and effectiveness of different strategies to prevent, diagnose, treat, and monitor health conditions to improve patient care.

18 Feb 2014

Sports medicine experts raise concern about female athlete triad syndrome

When an adolescent female patient comes to Nationwide Children's Hospital's Sports Medicine clinic, not only are these young women treated for their sports-related injury, but their sports medicine physician will also ask if they've missed any periods, because of a growing concern among female athletes.

18 Feb 2014

Researchers identify first biomarker for major depression

Teenage boys who show a combination of depressive symptoms and elevated levels of the 'stress hormone' cortisol are up to fourteen times more likely to develop major depression than those who show neither trait, according to research funded by the Wellcome Trust.

18 Feb 2014

New approach for delivering vaccines and for stimulating body's immune system to attack tumors

Many vaccines, including those for influenza, polio, and measles, consist of a killed or disabled version of a virus. However, for certain diseases, this type of vaccine is ineffective, or just too risky.

18 Feb 2014

NUS researchers discover promising treatment for anaplastic thyroid carcinoma

Anaplastic thyroid carcinoma is an aggressive type of cancer with a poor prognosis for which there is currently no effective treatment. Researchers from the National University of Singapore have discovered for the first time that an epithelial basement membrane protein, called laminin-5 gamma-2 (LAMC2), has the potential to be an ideal target for the treatment of ATC.

18 Feb 2014

Researchers are unraveling the mysteries of amyloid beta peptides in Alzheimer's disease

Alzheimer's disease has long been marked by progress -- but not the kind of progress the medical community seeks. It is the most common form of dementia among older Americans, and its risk increases with increasing age; for those living with the disease, its ravages get worse over time; and as we move into the 21st century, it will place a greater and greater burden on society.

18 Feb 2014

Heartier appetite linked to more rapid infant growth, weight gain

A heartier appetite is linked to more rapid infant growth and to genetic predisposition to obesity, according to two papers published in JAMA Pediatrics today (Monday).

18 Feb 2014

Researchers discover key role of actin in shutting down endocytosis during mitosis

Researchers from Warwick Medical School have discovered the key role of a protein in shutting down endocytosis during mitosis, answering a question that has evaded scientists for half a century.

18 Feb 2014

Researchers detail how psoralen blocks signaling pathway of HER2-positive cancers

A common compound known to fight lymphoma and skin conditions actually has a second method of action that makes it particularly deadly against certain aggressive breast tumors, researchers at Duke Medicine report.

18 Feb 2014

Scientists discover link between ageing process and hormone released from muscle after exercise

Scientists from Aston University (UK) have discovered a potential molecular link between Irisin, a recently identified hormone released from muscle after bouts of exercise, and the ageing process.

18 Feb 2014

Democrats' campaign plan: Confront health law issues, challenge GOP's stance

Democratic Party strategists urge candidates to talk about their ideas on how to fix the law and to assert that the Republicans' plans would make problems worse.

18 Feb 2014

Polyplus-transfection grants research license to NIH for PEI-mediated transfection applications

Polyplus-transfection SA, a privately-held company developing innovative technologies for molecular and cellular biology, announces today that it has granted two agencies of the United States National Institutes of Health a non-exclusive, research license to use Polyethylenimine (PEI) for in vitro transfection applications. The two agencies are the National Institute of Allergy and Infectious Diseases and the National Cancer Institute.

17 Feb 2014

Sleep duration impacts on genetic risk of depressive symptoms

Both long and short sleep durations are associated with an increased heritability of depression, study findings show.

17 Feb 2014

Blood pressure effects unclear in long-term stroke survivors

Long-term survivors of stroke whose blood pressure is at target levels have worse outcomes than those with slightly elevated levels, research suggests.

17 Feb 2014

Afatinib ‘first line’ for advanced mutation-positive lung cancer

Afatinib should be given as a first-line treatment for Asian patients with advanced, epidermal growth factor receptor mutation-positive, non-small-cell lung cancer, researchers recommend.

17 Feb 2014

Valproic acid metabolism and obesity: an interview with Dr. Namandjé Bumpus, Johns Hopkins Medicine

Valproic acid is one of the most widely prescribed drugs for the treatment of epilepsy. It has also been shown to be effective for the treatment of mood disorders and migraine headaches.

17 Feb 2014

Researchers conduct pioneering translational study on immediate antidepressant effect of DBS

A team of UCA researchers led by Professor Esther Berrocoso and in joint collaboration with the mental health research groups of the Centro de Investigación Biomédica en Red de Salud Mental have carried out a pioneering project in Spain.

17 Feb 2014

Study points to unique therapeutic approach for managing muscle-wasting conditions

New findings on why skeletal muscle stem cells stop dividing and renewing muscle mass during aging points up a unique therapeutic opportunity for managing muscle-wasting conditions in humans, says a new University of Colorado Boulder study.

17 Feb 2014

Subtle epigenetic change plays important role in correct segregation of chromosomes

Abnormal number of chromosomes is often associated with cancer development. In a new study published in the journal Nature Structural and Molecular Biology researchers at Karolinska Institutet in Sweden have shown that a subtle epigenetic change plays an important role in the correct segregation of chromosomes.

17 Feb 2014

Research News and Research

New drug patent may help overcome problems associated with MDR-TB

UT Southwestern receives grant to establish Center for Patient-Centered Outcomes Research

Sports medicine experts raise concern about female athlete triad syndrome

Researchers identify first biomarker for major depression

New approach for delivering vaccines and for stimulating body's immune system to attack tumors

NUS researchers discover promising treatment for anaplastic thyroid carcinoma

Researchers are unraveling the mysteries of amyloid beta peptides in Alzheimer's disease

Heartier appetite linked to more rapid infant growth, weight gain

Researchers discover key role of actin in shutting down endocytosis during mitosis

Researchers detail how psoralen blocks signaling pathway of HER2-positive cancers

Scientists discover link between ageing process and hormone released from muscle after exercise

Democrats' campaign plan: Confront health law issues, challenge GOP's stance

Polyplus-transfection grants research license to NIH for PEI-mediated transfection applications

Sleep duration impacts on genetic risk of depressive symptoms

Blood pressure effects unclear in long-term stroke survivors

Afatinib ‘first line’ for advanced mutation-positive lung cancer

Valproic acid metabolism and obesity: an interview with Dr. Namandjé Bumpus, Johns Hopkins Medicine

Researchers conduct pioneering translational study on immediate antidepressant effect of DBS

Study points to unique therapeutic approach for managing muscle-wasting conditions

Subtle epigenetic change plays important role in correct segregation of chromosomes

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