Genes News and Research

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Circadian clock proteins set the pace of plant growth

Scientists at the Centre for Research in Agricultural Genomics (CRAG) in Spain have identified the members of a protein family linked with the internal clocks of plants that act sequentially to restrict plant growth until just before daylight, according to a new study published in the journal Current Biology.

15 Jan 2018

Variations in bacterial strains can trigger varying immune responses, study states

A new study published in PLOS Pathogens revealed the role of genetic variations between different strains of the same bacterial species in inducing variations in immune system responses. Former studies have shown that susceptibility to infection with the same species of disease causing bacteria may vary among people.

15 Jan 2018

Past exposures influence immune response in children with acute respiratory tract infections

Acute respiratory tract infections (ARTI) are the leading global cause of death in early childhood, according to the Centers for Disease Control and Prevention.

12 Jan 2018

U.S. FDA approves first drug for patients with germline BRCA-mutated metastatic breast cancer

AstraZeneca and Merck, known as MSD outside the United States and Canada, today announced that the U.S. Food and Drug Administration has approved LYNPARZA (olaparib) for use in patients with deleterious or suspected deleterious germline BRCA-mutated (gBRCAm), human epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer who have been previously treated with chemotherapy in the neoadjuvant, adjuvant or metastatic setting.

12 Jan 2018

Discovery suggests new approach for targeting most-wanted molecular culprits in cancer

A discovery by scientists at Dana-Farber Cancer Institute and University of Texas Southwestern Medical Center presents drug developers with an entirely new tack in targeting one of the most-wanted molecular culprits in cancer.

12 Jan 2018

Study finds overall pattern of commonality between Huntington's and Parkinson's

A new study strongly suggests that the brains of people who have died of Huntington's disease (HD) and Parkinson's disease (PD) show a similar response to a lifetime of neurodegeneration, despite being two very distinct diseases.

12 Jan 2018

Researchers discover new type of botulinum neurotoxin from unexpected source

Researchers from the Quadram Institute have identified genes encoding a previously undiscovered version of the botulinum neurotoxin in bacteria from a cow's gut.

12 Jan 2018

The Virus That Causes Hand, Foot and Mouth Disease May Use Human Protein to Aid Infection

The human protein, prohibitin, may be used by the virus to enter motor neurons and cause the neurological complications of hand, foot and mouth disease.

12 Jan 2018

Study suggests shared genetic susceptibility to epilepsy and mood disorders

Mood disorders, including depression, are the most common comorbid conditions in individuals with epilepsy, but the cause remains unclear, according to a latest study by researchers at Columbia University's Mailman School of Public Health and Rutgers University.

12 Jan 2018

RAS dimers essential for causing cancer, study shows

Mutated RAS genes are some of the most common genetic drivers of cancer, especially in aggressive cancers like pancreatic and lung cancer, but no medicines that target RAS are available despite decades of effort.

12 Jan 2018

BRCA gene mutation does not raise the risk of death

BRCA gene mutation has been associated with cancers such as breast cancer. The BRCA gene mutation detection had resulted in a prophylactic double mastectomy for actress Angelina Jolie anticipating cancer. Now a new study has shown that having a BRCA gene mutation and being diagnosed with breast cancer does not raise the risk of death after diagnosis. The study was published in the latest issue of the journal The Lancet Oncology.

11 Jan 2018

Mount Sinai study uncovers potential link between Crohn's and Parkinson's in Jewish population

Mount Sinai Researchers have just discovered that patients in the Ashkenazi Jewish population with Crohn's disease (a chronic inflammatory of the digestive system) are more likely to carry the LRRK2 gene mutation.

11 Jan 2018

Unhealthy diet makes the body's defenses more aggressive in the long term

The immune system reacts similarly to a high fat and high-calorie diet as to a bacterial infection. This is shown by a recent study led by the University of Bonn.

11 Jan 2018

Study identifies enzyme that regulates inflammation and metabolism in fat tissue

The human body has two primary kinds of fat--white fat, which stores excess calories and is associated with obesity, and brown fat, which burns calories in order to produce heat and has garnered interest as a potential means of combating obesity.

11 Jan 2018

Study finds genetic variations linked to BMI and obesity risk

It's not just diet and physical activity; your genes also determine how easily you lose or gain weight. In a study published in the January issue of Nature Genetics, researchers at the Icahn School of Medicine at Mount Sinai and other institutions of the Genetic Investigation of Anthropometric Traits consortium found 13 genes that carry variations associated with body mass index.

10 Jan 2018

Researchers find evidence for genetic relationship between epileptic seizures and depression

From the time of Hippocrates, physicians have suspected a link between epilepsy and depression. Now, for the first time, scientists at Rutgers University-New Brunswick and Columbia University have found evidence that seizures and mood disorders such as depression may share the same genetic cause in some people with epilepsy, which may lead to better screening and treatment to improve patients' quality of life.

10 Jan 2018

Biomarkers may help predict prognosis of gastric cancer patients with alcohol consumption habits

Alcohol consumption has been identified as a modifiable risk factor for cancers such as gastric cancer. A new report in the The American Journal of Pathology sheds light on how specific proteins interact with alcohol, and how that interplay impacts survival and response to platinum-based adjuvant chemotherapy in patients with gastric cancer who may or may not still be drinking.

10 Jan 2018

Genes News and Research

Circadian clock proteins set the pace of plant growth

Variations in bacterial strains can trigger varying immune responses, study states

Past exposures influence immune response in children with acute respiratory tract infections

U.S. FDA approves first drug for patients with germline BRCA-mutated metastatic breast cancer

Discovery suggests new approach for targeting most-wanted molecular culprits in cancer

Study finds overall pattern of commonality between Huntington's and Parkinson's

Researchers discover new type of botulinum neurotoxin from unexpected source

The Virus That Causes Hand, Foot and Mouth Disease May Use Human Protein to Aid Infection

Study suggests shared genetic susceptibility to epilepsy and mood disorders

RAS dimers essential for causing cancer, study shows

BRCA gene mutation does not raise the risk of death

Mount Sinai study uncovers potential link between Crohn's and Parkinson's in Jewish population

Unhealthy diet makes the body's defenses more aggressive in the long term

Study identifies enzyme that regulates inflammation and metabolism in fat tissue

Study finds genetic variations linked to BMI and obesity risk

Researchers find evidence for genetic relationship between epileptic seizures and depression

Biomarkers may help predict prognosis of gastric cancer patients with alcohol consumption habits

CHOP researchers explore effective nutritional therapies for mitochondrial disease

Scientists find gene that predisposes Greenlanders to obesity

Scientists uncover how good bacteria regulate genes

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