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Scientists show how hemizygous deletion can contribute to cancer

Chromosomal deletions in DNA often involve just one of two gene copies inherited from either parent. But scientists haven't known how a deletion in one gene from one parent, called a "hemizygous" deletion, can contribute to cancer.

28 May 2012

Link between increase in assisted living options and decline in nursing home occupancy

A new study finds an association between an increase in assisted living options, which provide older adults with an array of services such as help with everyday tasks in homelike settings, and a decline in nursing home occupancy. This shift in delivery of care has both positive and negative implications for seniors.

25 May 2012

Study sheds light on role of microglia in the normal brain

Researchers have shown in mice how immune cells in the brain target and remove unused connections between brain cells during normal development. This research, supported by the National Institutes of Health, sheds light on how brain activity influences brain development, and highlights the newly found importance of the immune system in how the brain is wired, as well as how the brain forms new connections throughout life in response to change.

24 May 2012

Optogenetic Therapies for Vision workshop to be held on June 1

The Foundation Fighting Blindness and Massachusetts Eye and Ear will host the Optogenetic Therapies for Vision workshop on Friday, June 1, from 8 a.m.-6 p.m., in Boston.

24 May 2012

Brain cells prune circuits in the brain by eating away excess synapses

We’re born with our brains prewired, but as information comes in from our environment, this circuitry is updated. A study from Boston Children’s Hospital provides a new glimpse of how this happens: Brain cells known as microglia, tuned into the crosstalk between neurons, literally engulf unnecessary connections, known as synapses, and prune them away.

24 May 2012

CMS sticks with Medicare coverage of PSA test

The federal government is not changing coverage plans "at this time." Meanwhile, a number of urologists and other medical specialists raise concerns that new recommendations against prostate cancer screening will hurt men's health.

24 May 2012

Study provides new clues about health-damaging molecular changes by eating high-fat foods

A University of Michigan Health System study provides new clues about the health-damaging molecular changes set in motion by eating high-fat foods.

23 May 2012

New clinical trial to evaluate HSP90 inhibitor plus hormonal therapy for breast cancer

Pushed to the brink of survival, the hyper-driven cells of a cancerous tumor tap into an ancient system that has helped organisms cope with internal stresses and environmental challenges since life began. As an integral part of this system, heat shock protein 90 (HSP90) has been shown to help malignant cells accommodate the genetic changes and profound disturbances in normal biology that occur in cancers.

23 May 2012

Studies of technological innovations presented at DDW annual meeting

Studies of technological innovations being presented for the first time at Digestive Disease Week- (DDW) showed increased accuracy coupled with decreased cost, time or invasiveness of gastrointestinal procedures. Use of a new high-definition colonoscope, for example, improved physician confidence in diagnosing small polyps, potentially reducing the amount of polyps sent for pathology analysis and the associated costs.

From Evident Corporation - Life Sciences 22 May 2012

Socioeconomic factors associated with skin cancer screening

When it comes to getting screened for skin cancer, only one in 14 U.S. Hispanic adults is shown to have ever gone through the process, compared to one in four non-Hispanic white adults. Research from The Cancer Institute of New Jersey (CINJ) shows socioeconomic factors such as lack of health insurance and poorer access to healthcare serve as barriers for Hispanics who might otherwise receive this potentially lifesaving check-up.

22 May 2012

Data from EarlySense contact-free monitor clinical study presented at ATS conference

EarlySense, a market leader in proactive patient care solutions, announced today the results of a clinical study conducted at a Dignity Health Hospital. The data was presented today in a poster presentation titled: Effect Of Contactless Continuous Patient Monitoring In A Medical-Surgical Unit On Intensive Care Unit Transfers: A Controlled Clinical Trial at the ATS International Conference in San Francisco.

22 May 2012

CHDI, Lundbeck enter collaboration to investigate targeted therapy for Huntington's disease

CHDI Foundation, Inc. and Lundbeck today announced a research collaboration to investigate a targeted therapy for Huntington's disease (HD). Currently, no treatment exists to slow or halt the progression of HD, a challenging hereditary neurodegenerative disease characterized by a triad of behavioral, cognitive, and motor symptoms.

21 May 2012

Regenerative medicine researchers explore innovative ways to treat childhood conditions

About 3 percent of the babies born in the United States have a birth defect. Children without a birth defect are also susceptible to injury or disease. At The University of Texas Health Science Center at Houston (UTHealth), regenerative medicine researchers are exploring innovative ways to treat these conditions.

21 May 2012

Treatment of early stage prostate cancer can also result in improved QOL for men with LUTS

Treatment of early stage prostate cancer can also result in improved quality of life for a subgroup of men who suffer from lower urinary tract symptoms (LUTS), according to an abstract of a Beth Israel Deaconess Medical Center-led study presented to the American Urological Association.

21 May 2012

Study uncovers distinct subtype of prostate cancer

A collaborative expedition into the deep genetics of prostate cancer has uncovered a distinct subtype of the disease, one that appears to account for up to 15 percent of all cases, say researchers at Weill Cornell Medical College, the Broad Institute of MIT and Harvard and the Dana-Farber Cancer Institute.

21 May 2012

Three-drug combo harmful for patients with idiopathic pulmonary fibrosis

A combination of three drugs used worldwide as the standard of care for a serious lung disease puts patients in danger of death or hospitalization, and should not be used together to treat the disease, called idiopathic pulmonary fibrosis, according to the surprising results of a rigorous independent study.

21 May 2012

Specialized high volume centers linked with lower rates of death and disability from aSAH

People with bleeding brain aneurysms have the best chance of survival and full recovery if they receive aggressive emergency treatment from a specialized team at a hospital that treats a large number of patients like them every year, according to new guidelines just published by the American Stroke Association.

19 May 2012

Janssen’s NUCYNTA ER tablets more effective in providing pain management in adults with DPN

Janssen Pharmaceuticals, Inc. today announced the results of an investigational Phase 3 study suggesting NUCYNTA ER (tapentadol) extended-release tablets were significantly more effective than placebo in providing pain management among adults with chronic moderate to severe, painful diabetic peripheral neuropathy.

18 May 2012

APS announces recipients of prestigious achievement awards

The American Pain Society (APS), www.ampainsoc.org, today announced the recipients of its prestigious achievement awards during the organization's annual scientific meeting. APS rewards excellence in pain management with awards for career achievement, pain scholarship, education and public service, advocacy on behalf of children, outstanding service to APS, early career achievements and journalism.

18 May 2012

Kudzu root components may treat alcoholism and curb binge drinking

An extract of the Chinese herb kudzu dramatically reduces drinking and may be useful in the treatment of alcoholism and curbing binge drinking, according to a new study by McLean Hospital and Harvard Medical School researchers.

18 May 2012

Medical School News and Research

Scientists show how hemizygous deletion can contribute to cancer

Link between increase in assisted living options and decline in nursing home occupancy

Study sheds light on role of microglia in the normal brain

Optogenetic Therapies for Vision workshop to be held on June 1

Brain cells prune circuits in the brain by eating away excess synapses

CMS sticks with Medicare coverage of PSA test

Study provides new clues about health-damaging molecular changes by eating high-fat foods

New clinical trial to evaluate HSP90 inhibitor plus hormonal therapy for breast cancer

Studies of technological innovations presented at DDW annual meeting

Socioeconomic factors associated with skin cancer screening

Data from EarlySense contact-free monitor clinical study presented at ATS conference

CHDI, Lundbeck enter collaboration to investigate targeted therapy for Huntington's disease

Regenerative medicine researchers explore innovative ways to treat childhood conditions

Treatment of early stage prostate cancer can also result in improved QOL for men with LUTS

Study uncovers distinct subtype of prostate cancer

Three-drug combo harmful for patients with idiopathic pulmonary fibrosis

Specialized high volume centers linked with lower rates of death and disability from aSAH

Janssen’s NUCYNTA ER tablets more effective in providing pain management in adults with DPN

APS announces recipients of prestigious achievement awards

Kudzu root components may treat alcoholism and curb binge drinking

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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