Antibodies News and Research

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Gene therapy advance shows potential for developing improved treatment for hemophilia

A virus that typically infects insects could help with the development of gene therapy treatment for Hemophilia A, a condition in which even a bump on the knee can cause serious internal bleeding in people.

22 Aug 2005

Experimental vaccine can prime the immune system to help fight an aggressive form of lymphoma

Researchers at The University of Texas M. D. Anderson Cancer Center and the National Cancer Institute have found that an experimental vaccine can prime the immune system to help fight an aggressive form of lymphoma, even though prior therapy had eliminated virtually all of the B cells thought necessary to mount such a defense.

22 Aug 2005

Reasons for complications with kidney failure patients

Mayo Clinic researchers searching for explanations of high mortality rates among kidney failure patients undergoing hemodialysis are focusing their attention on the use of heparin, a drug used to reduce clotting of the blood.

18 Aug 2005

New hope for those deaf from immune system attack

A new study may one day help those deafened by immune system attack, and possibly also lead to a test that could show which patients may be helped by immediate steroid treatment.

16 Aug 2005

Pfizer acquires antibody discovery company Bioren

Pfizer and Bioren today announced the completion of a transaction in which Pfizer purchased all outstanding stock of Bioren for an undisclosed amount.

15 Aug 2005

Infusion nurses examine need for standards of practice in immunoglobulin therapy

A review article published in the July/August 2005 Journal of Infusion Nursing examines the need for established treatment guidelines to support doctors and nurses in correctly dosing and administering intravenous immunoglobulin (IVIG) as replacement therapy in patients with primary immunodeficiency (PI) disorders, who do not produce adequate levels of antibodies essential in fighting infectious diseases.

13 Aug 2005

Plasma exchange treatment shown most helpful for severe attacks in subtype of MS patients

A Mayo Clinic study demonstrates that only those multiple sclerosis (MS) patients with evidence for antibody deposition or complement activation -- immune cells that can cause tissue destruction -- in their lesions are likely to respond to plasma exchange, a treatment for acute MS attacks.

11 Aug 2005

Nasal vaccination with a proteosome-based adjuvant and glatiramer acetate clears beta-amyloid in a mouse model of Alzheimer's disease

Alzheimer disease (AD) is the most common form of senile dementia, with no effective treatment available. In a study appearing online on August 11 in advance of print publication of the September 1 issue of the Journal of Clinical Investigation, Howard Weiner and colleagues from Harvard describe a novel immunologic approach for the treatment of AD.

11 Aug 2005

Ground-breaking discoveries that provide hope of an alternative treatment option for haemophilia sufferers

Haemophilia is a hereditary blood disease, primarily affecting males, where the blood fails to clot causing potentially life-threatening 'bleeds'. About one in 6000 Australian males is born with haemophilia in severe, moderate or mild form. People with haemophilia rely on intravenous infusion of recombinant Factor VIII clotting protein.

11 Aug 2005

Researchers develop new diagnostic methods to better detect future monkeypox or smallpox outbreaks

The research also sheds new light on the 2003 monkeypox outbreak in the Midwest - monkeypox is closely related to smallpox. This new information suggests that the 2003 outbreak was larger than the 72 cases reported by the Centers for Disease Control and Prevention (CDC).

9 Aug 2005

U.S. company wants to commercialise breast milk

It has long been acknowledged that breast milk, with its minerals, digestive enzymes and antibodies, keeps babies healthy and boosts their intelligence.

7 Aug 2005

More than fifty percent of the U.S. population tested positive to one or more allergens

The new findings, based on data from the third National Health and Nutrition Examination Survey (NHANES III), shows that 54.3% of individuals aged 6-59 years old had a positive skin test response to at least one of the 10 allergens tested.

4 Aug 2005

Discovery may lead to new diagnostic tests for immunoglobulin A (IgA) deficiency and common variable immunodeficiency (CVID)

Defects in a single gene can result in two immune system disorders that leave affected individuals vulnerable to frequent or unusually severe infections, according to new findings reported in the August issue of Nature Genetics.

4 Aug 2005

New laser therapy that destroys cancer cells but leaves healthy ones unharmed

Scientists at Stanford University have developed a new laser therapy that destroys cancer cells but leaves healthy ones unharmed. The new, non-invasive treatment is described in a study published in the Aug. 1 online edition of the Proceedings of the National Academy of Sciences (PNAS).

2 Aug 2005

Two studies reveal how plague disables immune system

Two studies by researchers at the University of Chicago show how the bacteria that cause the plague manage to outsmart the immune system and how, by slightly altering one of the microbe's tools, the researchers produced what may be the first safe and effective vaccine.

1 Aug 2005

Specialized immune-system B cells play dual role in triggering both kinds of immunity - innate and acquired

A specialized subpopulation of the antibody-producing B cells of the immune system plays a "double-barreled" role in triggering both kinds of immunity - innate and acquired, Duke University Medical Center immunologists have discovered.

26 Jul 2005

Gene that regulates normal embryonic development is found at high levels in virtually all forms of breast cancer

A gene that appears to help regulate normal embryonic development is found at high levels in virtually all forms of breast cancer, according to a new study led by Laszlo Radvanyi, Ph.D., associate professor of breast and melanoma medical oncology at The University of Texas M. D. Anderson Cancer Center.

25 Jul 2005

New design for HIV vaccine trials in animals

Emory University researchers have proposed a new design for HIV vaccine trials in animals that would more closely mimic how humans are exposed to the virus - potentially giving AIDS researchers a more effective tool in developing successful treatments to prevent HIV infection.

20 Jul 2005

Scientists have identified the first reported case in Asia of primate-to-human transmission of simian foamy virus

...a retrovirus found in macaques and other primates that so far has not been shown to cause disease in humans.

13 Jul 2005

Blood testing links common foods and irritable bowel syndrome

Researchers using comparison trials determined that irritable bowel syndrome (IBS) patients have elevated food-specific IgG4 antibodies to common foods such as wheat, beef, pork, lamb, and soya bean. These findings are published in the July issue of The American Journal of Gastroenterology.

13 Jul 2005

Antibodies News and Research

Gene therapy advance shows potential for developing improved treatment for hemophilia

Experimental vaccine can prime the immune system to help fight an aggressive form of lymphoma

Reasons for complications with kidney failure patients

New hope for those deaf from immune system attack

Pfizer acquires antibody discovery company Bioren

Infusion nurses examine need for standards of practice in immunoglobulin therapy

Plasma exchange treatment shown most helpful for severe attacks in subtype of MS patients

Nasal vaccination with a proteosome-based adjuvant and glatiramer acetate clears beta-amyloid in a mouse model of Alzheimer's disease

Ground-breaking discoveries that provide hope of an alternative treatment option for haemophilia sufferers

Researchers develop new diagnostic methods to better detect future monkeypox or smallpox outbreaks

U.S. company wants to commercialise breast milk

More than fifty percent of the U.S. population tested positive to one or more allergens

Discovery may lead to new diagnostic tests for immunoglobulin A (IgA) deficiency and common variable immunodeficiency (CVID)

New laser therapy that destroys cancer cells but leaves healthy ones unharmed

Two studies reveal how plague disables immune system

Specialized immune-system B cells play dual role in triggering both kinds of immunity - innate and acquired

Gene that regulates normal embryonic development is found at high levels in virtually all forms of breast cancer

New design for HIV vaccine trials in animals

Scientists have identified the first reported case in Asia of primate-to-human transmission of simian foamy virus

Blood testing links common foods and irritable bowel syndrome

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