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Using nanotheranostics approach to treat cancer

The concept of theranostics revolves around the stratification of patients into specific groups based on their response to different treatments and their disease risks.

10 Jun 2020

EHR data could help avoid pre-term deliveries for pregnant COVID-19 patients

Using electronic health record data to simulate drug trials for pregnant patients could one day offer a solution to the current practice of delivering babies pre-term if an expectant mother contracts COVID-19, according to a position paper published in Nature Medicine.

10 Jun 2020

Baboon could prove to be a relevant model to test Alzheimer's disease interventions

Scientists at Texas Biomedical Research Institute's Southwest National Primate Research Center recently published findings indicating the baboon could prove to be a relevant model to test therapeutics and interventions for neurodegenerative diseases, such as early stage Alzheimer's and related dementias.

10 Jun 2020

Cannabis poisonings in children results from intentional use along with alcohol, illicit drugs

Most cannabis poisoning incidents involving children resulted from the intentional use of cannabis combined with alcohol, illicit drugs and/or medication, new research suggests.

10 Jun 2020

Unique antiviral action of cholesterol 25-hydroxylase against SARS-CoV-2

A new study by U.S. and Chinese researchers, currently available on the bioRxiv* preprint server, demonstrates how cholesterol 25-hydroxylase and its enzymatic product 25-hydroxycholesterol can inhibit membrane fus

10 Jun 2020

COVID-19 mouse model could accelerate the search for treatments, vaccines

The global effort to quickly develop drugs and vaccines for COVID-19 has been hampered by limited numbers of laboratory mice that are susceptible to infection with SARS-CoV-2, the virus that causes COVID-19.

10 Jun 2020

Key enzyme that contributes to eczema identified

Researchers at the University of British Columbia (UBC) and Vancouver Coastal Health Research Institute have identified a key enzyme that contributes to eczema, which may lead to better treatment to prevent the skin disorder's debilitating effects.

10 Jun 2020

Tocilizumab in Critical COVID-19 Patients

A new study by scientists at Metro Infectious Disease Consultants and published on the preprint server medRxiv* in June 2020 reports that the cytokine blocker tocilizumab is a useful adjunct to supportive medical care in severe COVID-19, with increased survival and a lower requirement for mechanical ventilation.

10 Jun 2020

Study shows safety of new cell therapy approaches for kidney transplant recipients

A large international study coordinated by University Hospital Regensburg and Charité - Universitätsmedizin Berlin has demonstrated the safety of new cell therapy approaches for use in kidney transplant recipients.

10 Jun 2020

Specific immune signature identified in COVID-19 patients

Researchers at King’s College London and collaborators have identified an “immune signature” that could help researchers better understand coronavirus disease 2019 (COVID-19) and serve as a valuable resource for predicting patient prognosis and informing clinical risk-based stratification.

10 Jun 2020

Key recommendations on genetic testing of men for prostate cancer

Prostate cancer is a leading cause of death from cancer in the US and especially in the Philadelphia region. Consistently, Philadelphia has outpaced the state of PA and the nation in diagnoses and death from prostate cancer.

10 Jun 2020

NIH-funded researchers to assess drugs prescribed to treat COVID-19 in children

Researchers funded by the National Institutes of Health have launched an effort to evaluate drugs prescribed to treat COVID-19 in infants, children and adolescents across the country. The study leverages an existing clinical trial that examines drugs that are prescribed off-label to children for a variety of medical conditions.

10 Jun 2020

Synthesized tumor cells help diagnose cancer and optimize treatment

Researchers in Japan have replicated cancer cells from diseased bladder tissue in dogs, minimizing the use of costly stem cell products.

10 Jun 2020

BAM15 could be an effective drug for treating obesity and related diseases

A new study offers the first evidence that a protein named BAM15 acts as an energy uncoupler and could be an effective drug for treating obesity and related diseases.

10 Jun 2020

Study provides new evidence that liver dysfunction may lead to heart disease

A new study that looks closely at the cardiac health of flies provides new evidence that liver dysfunction may lead to deterioration of the heart.

10 Jun 2020

Research team provides new insights on the communication between liver and brain

A research team in Vienna is investigating how calorie intake, liver activity and fat storage interact and what role the central nervous system plays in this.

10 Jun 2020

Immuno-oncology may accelerate the development of treatments for COVID-19

Researchers at Roswell Park Comprehensive Cancer Center have been actively engaged in the effort to develop treatments or other control strategies that can help communities worldwide to address the impacts of the COVID-19 pandemic.

10 Jun 2020

Weighing the risks and benefits of drug screening

Little evidence supports the new recommendations for clinical screening for drug use. Do the potential benefits outweigh the potential harms?

10 Jun 2020

Detachable microneedle depots deliver therapeutic stem cells to injured tissue sites

Mesenchymal stem cells (MSCs) are multipotent in that they naturally replenish the cell types that build our bone, cartilage and adipose tissues.

10 Jun 2020

Registered COVID-19 clinical trials lack key features to optimize their scientific value

Most of the registered clinical trials of potential treatments for COVID-19 underway as of late March were designed in ways that will greatly limit their value in understanding potential treatments, according to a study from researchers at Johns Hopkins Bloomberg School of Public Health.

10 Jun 2020