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Scientists show how immune system can be modulated by manipulation of sugar metabolism

In its attempt to fight a serious bacterial infection, caused by listeria, for example, the immune system can become so over-activated that the resulting inflammatory response and its consequences can quickly lead to death.

21 Aug 2017

Animal study shows how being bullied can have dramatic effects on sleep

New research from McLean Hospital neuroscientists shows in an animal model that being bullied can have long-term, dramatic effects on sleep and other circadian rhythm-related functions, symptoms that are characteristic of clinical depression and other stress-induced mental illnesses.

10 Aug 2017

Researcher receives NIH grant to study genetic mutation that prevents tooth formation

Inherited genetic mutations can rob up to 7 percent of the population of their smile. Several genes are important for the placement and patterning of teeth.

9 Aug 2017

High-frequency alternating magnetic fields can help destroy bacterial biofilms

A short exposure to an alternating magnetic field might someday replace multiple surgeries and weeks of IV antibiotics as treatment for stubborn infections on artificial joints, new research suggests.

9 Aug 2017

Mice study shows why women with obesity have more aggressive breast cancer

Women with obesity are more likely to get breast cancer, and a number of studies have provided a reasonable explanation why: after menopause, fat tissue manufactures estrogen, and the estrogen then promotes tumor growth.

8 Aug 2017

New clinical trial examines potential role of drug combination therapy to eliminate LAM cells

Researchers at the University of Cincinnati begin a new clinical trial this fall, examining the potential role of a drug combination therapy to eliminate lymphangioleiomyomatosis (LAM) cells.

7 Aug 2017

Protein that protects fetus during pregnancy could help treat atopic dermatitis

A protein which protects the fetus during pregnancy, HLA-G1, shows high potential for treating atopic dermatitis and other related diseases.

4 Aug 2017

Biomedical researcher wins $1.9 million federal grant to develop enhanced influenza vaccines

Dr. Sang-Moo Kang, professor in the Institute for Biomedical Sciences at Georgia State University, has renewed a four-year, $1.9 million federal grant to develop influenza vaccines that offer enhanced protection against a broad range of influenza virus strains.

31 Jul 2017

GW researchers find nitric oxide-releasing nanoparticles as viable treatment for fungal skin infections

George Washington University researchers have found that topically applied nitric oxide-releasing nanoparticles (NO-np) are a viable treatment for deep fungal infections of the skin caused by dermatophytes, for which the current standard of care is treatment with systemic antifungals.

31 Jul 2017

New substance restores brain function in Alzheimer's animal model

The protein amyloid beta is believed to be the major cause of Alzheimer's disease. Substances that reduce the production of amyloid beta, such as BACE inhibitors, are therefore promising candidates for new drug treatments.

28 Jul 2017

Researchers find neuroprotective effects of trigeminal nerve stimulation in severe TBI

Researchers at the Feinstein Institute for Medical Research and the department of neurosurgery at the Hofstra Northwell School of Medicine, announced today that they have published a paper with research findings that could have implications for the treatment of many neurological conditions, including severe traumatic brain injury (TBI).

28 Jul 2017

Spider threads show great potential for nerve and tissue repair

The golden orb-weaver spider from Tanzania spins such strong webs that Tanzanian fishermen use them for fishing.

28 Jul 2017

Neuro-oncology scientists discover unique molecular mechanism that maintains glioma stem cells

Glioblastoma is a primary brain tumor with dismal survival rates, even after treatment with surgery, chemotherapy, and radiation.

25 Jul 2017

Established therapeutic drugs may be effective against childhood dementia

Although dementia is most often seen in adults, childhood or adolescent dementia does occur. A team of researchers from the University of Würzburg believes that established therapeutic drugs might be effective against childhood dementia.

24 Jul 2017

New study links unhealthy diet during pregnancy to mental health disorders in offspring

A high-fat diet not only creates health problems for expectant mothers, but new research in an animal model suggests it alters the development of the brain and endocrine system of their offspring and has a long-term impact on offspring behavior.

21 Jul 2017

Study provides deeper understanding into genetic basis of neuropsychiatric disorders

A study by scientists at the Children's Medical Center Research Institute at UT Southwestern is providing insight into the genetic basis of neuropsychiatric disorders.

21 Jul 2017

Bacterium S. gallolyticus appears to actively promote development of colorectal cancer

Colorectal cancer is fairly treatable when caught early with regular screenings, but it is still the second-leading cause of cancer-related deaths in American men and the third-leading cause in women.

17 Jul 2017

Feinstein Institute professor finds protein as potential cause for lupus

Leading rheumatologist and Feinstein Institute for Medical Research Professor Betty Diamond, MD, may have identified a protein as a cause for the adverse reaction of the immune system in patients suffering from lupus.

14 Jul 2017

Targeting immune cells could lead to new treatments for pulmonary fibrosis

Northwestern Medicine scientists have demonstrated that a unique population of immune cells plays a key role in the development of pulmonary fibrosis, and showed that targeting such cells could lead to new treatments for the disease.

13 Jul 2017

Targeting acid metabolite reduces size and spread of breast cancer

It's a metabolite found in essentially all our cells that, like so many things, cancer overexpresses. Now scientists have shown that when they inhibit 20-HETE, it reduces both the size of a breast cancer tumor and its ability to spread to the lungs.

12 Jul 2017

Animal Model News and Research

Scientists show how immune system can be modulated by manipulation of sugar metabolism

Animal study shows how being bullied can have dramatic effects on sleep

Researcher receives NIH grant to study genetic mutation that prevents tooth formation

High-frequency alternating magnetic fields can help destroy bacterial biofilms

Mice study shows why women with obesity have more aggressive breast cancer

New clinical trial examines potential role of drug combination therapy to eliminate LAM cells

Protein that protects fetus during pregnancy could help treat atopic dermatitis

Biomedical researcher wins $1.9 million federal grant to develop enhanced influenza vaccines

GW researchers find nitric oxide-releasing nanoparticles as viable treatment for fungal skin infections

New substance restores brain function in Alzheimer's animal model

Researchers find neuroprotective effects of trigeminal nerve stimulation in severe TBI

Spider threads show great potential for nerve and tissue repair

Neuro-oncology scientists discover unique molecular mechanism that maintains glioma stem cells

Established therapeutic drugs may be effective against childhood dementia

New study links unhealthy diet during pregnancy to mental health disorders in offspring

Study provides deeper understanding into genetic basis of neuropsychiatric disorders

Bacterium S. gallolyticus appears to actively promote development of colorectal cancer

Feinstein Institute professor finds protein as potential cause for lupus

Targeting immune cells could lead to new treatments for pulmonary fibrosis

Targeting acid metabolite reduces size and spread of breast cancer

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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