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Researchers conduct first-in-man clinical trial for new stem cell technology

Institutes and centres under the SingHealth Duke-NUS Academic Medical Centre (AMC) are joining hands together with Singapore's first private cord blood bank, Cordlife Group Limited (Cordlife), to test a novel technology that expands the number of blood-forming stem cells from stored umbilical cord blood (UCB) in a first-in-man study in Singapore.

12 May 2021

Microneedle patch delivers antibiotics to effectively reduce MRSA bacteria in the skin

MRSA skin infections are often treated with intravenous injection of antibiotics, which can cause significant side effects and promote the development of resistant bacterial strains.

10 May 2021

Four-part small-molecule cocktail can prevent cellular stress

Researchers at the National Institutes of Health (NIH) have devised a four-part small-molecule cocktail that can protect stem cells called induced pluripotent stem cells (iPSCs) from stress and maintain normal stem cell structure and function.

4 May 2021

Scientists develop an ultrasonic imaging system to visualize cell abnormalities in 3D

Scientists at the University of Nottingham have developed an ultrasonic imaging system, which can be deployed on the tip of a hair-thin optical fiber, and will be insertable into the human body to visualize cell abnormalities in 3D.

30 Apr 2021

New study reveals mechanisms that result in lethal COVID-19

A new study is drawing the most detailed picture yet of SARS-CoV-2 infection in the lung, revealing mechanisms that result in lethal COVID-19, and may explain long-term complications and show how COVID-19 differs from other infectious diseases.

30 Apr 2021

Single protein could be a new target for delaying onset of aging symptoms in the brain

It is not every day that scientists come across a phenomenon so fundamental that it is observed across fruit flies, rodents and humans.

29 Apr 2021

Researchers develop first 3D organoid models of the pancreas from human stem cells

This year, more than 60,000 adults in the United States will be diagnosed with pancreatic cancer and, statistically, as few as 10 percent will survive five years after diagnosis, according to the American Cancer Society.

28 Apr 2021

First-of-its-kind method cryopreserves fruit fly embryos in liquid nitrogen

Cryopreservation, or the long-term storage of biomaterials at ultralow temperatures, has been used across cell types and species.

28 Apr 2021

Study reveals mechanisms that cause muscle weakness in patients with Becker disease

Muscle weakness in patients with Becker disease is caused by unusual electrical activity in muscle fibres termed 'plateau potentials' that make them temporarily inactive, says a study published today in eLife.

27 Apr 2021

Scientists identify many genes that are important in fruit flies' neuron development

Neurons result from a highly complex and unique series of cell divisions. For example, in fruit flies, the process starts with stem cells that divide into mother cells (progenitor cells), that then divide into precursor cells that eventually become neurons.

27 Apr 2021

UCI biologists develop new mouse model to study late-onset Alzheimer's disease

University of California, Irvine biologists have developed a new genetically engineered mouse model that, unlike its predecessors, is based on the most common form of Alzheimer's disease.

27 Apr 2021

New platform helps non-experts use AI to analyze microscopy images

A new, freely available platform helps non-experts use artificial intelligence to analyze microscopy images. The platform has been developed at Åbo Akademi University in Finland and Instituto Gulbenkian de Ciência, Portugal, and will be of big help in research and diagnostics using modern day microscopes.

23 Apr 2021

Researchers discover molecule that provides dual protection against vascular inflammation

A multidisciplinary team of researchers from Duke-NUS Medical School and the Agency for Science, Technology and Research (A*STAR) in Singapore discovered a new mitochondrial peptide called MOCCI that plays an important role in regulating inflammation of blood vessel and immunity.

22 Apr 2021

New nanomedicine device is effective for treating glioblastoma multiforme

A micro-sized polymeric net wrapping around brain tumors, just like a fishing net around a shoal of fish: this is the microMESH, a new nanomedicine device capable to conform around the surface of tumor masses and efficiently deliver drugs.

20 Apr 2021

Simple dietary supplement ameliorates schizophrenic traits in mice

A simple dietary supplement reduces behavioral symptoms in mice with a genetic mutation that causes schizophrenia.

19 Apr 2021

SARS-CoV-2 does not directly infect the brain but can inflict neurological damage

SARS-CoV-2, the virus that causes COVID-19, likely does not directly infect the brain but can still inflict significant neurological damage, according to a new study from neuropathologists, neurologists, and neuroradiologists at Columbia University Vagelos College of Physicians and Surgeons.

17 Apr 2021

Researchers develop a rapid method to assess thirdhand smoke contaminants in household fabrics

A study led by scientists at the University of California, Riverside, has found chemicals in thirdhand smoke, or THS, get extracted more readily from household fabrics in a humid environment than in a dry one.

16 Apr 2021

S-2-hydroxyglutarate keeps endothelial cells in a dormant state, reveals study

The inner surface of blood vessels is lined by a wafer-thin layer of cells known as the endothelium, which forms a crucial barrier between blood and the surrounding tissue.

16 Apr 2021

Series of reviews discuss key issues in chronic kidney disease and bone disorders

Metabolic bone disease is a common complication of chronic kidney disease (CKD) and involves a broad spectrum of disorders of mineral metabolism that result in both skeletal and extra-skeletal consequences.

15 Apr 2021

Experts to discuss advanced cancer cell and gene therapies at Summit 2021

April 29 marks a pivotal moment in cancer research when the world's brightest minds come together to discuss how to translate the success of CAR T-cell therapies for blood cancers into successful cell and gene therapies for the most complex and deadly solid tumor cancers.

15 Apr 2021

Cell Biology News and Research

Researchers conduct first-in-man clinical trial for new stem cell technology

Microneedle patch delivers antibiotics to effectively reduce MRSA bacteria in the skin

Four-part small-molecule cocktail can prevent cellular stress

Scientists develop an ultrasonic imaging system to visualize cell abnormalities in 3D

New study reveals mechanisms that result in lethal COVID-19

Single protein could be a new target for delaying onset of aging symptoms in the brain

Researchers develop first 3D organoid models of the pancreas from human stem cells

First-of-its-kind method cryopreserves fruit fly embryos in liquid nitrogen

Study reveals mechanisms that cause muscle weakness in patients with Becker disease

Scientists identify many genes that are important in fruit flies' neuron development

UCI biologists develop new mouse model to study late-onset Alzheimer's disease

New platform helps non-experts use AI to analyze microscopy images

Researchers discover molecule that provides dual protection against vascular inflammation

New nanomedicine device is effective for treating glioblastoma multiforme

Simple dietary supplement ameliorates schizophrenic traits in mice

SARS-CoV-2 does not directly infect the brain but can inflict neurological damage

Researchers develop a rapid method to assess thirdhand smoke contaminants in household fabrics

S-2-hydroxyglutarate keeps endothelial cells in a dormant state, reveals study

Series of reviews discuss key issues in chronic kidney disease and bone disorders

Experts to discuss advanced cancer cell and gene therapies at Summit 2021

Driving innovation in drug discovery with in vitro biology solutions eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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