Immunization News and Research

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Nanozymes to the rescue - potential role in fighting COVID-19

Over the last few decades, researchers have developed artificial enzymes for many applications. Recently, they deployed nanomaterial-based enzyme mimetics or nanozymes in diagnosis and therapeutics. Nanozymes find applications in various biomedical applications, including antiviral agents and cancer therapy.

8 Jun 2021

Repeated low-dose dose exposure to SARS-CoV-2 may protect against severe COVID-19

The Italian authors of this paper, published in the journal Viruses, have taken this hypothesis and expanded it to include viral particles suspended in the air or on inanimate objects as a possible source of T cell immunity due to the repeated low-dose exposure, potentially explaining virus immunity found in non-infected individuals.

7 Jun 2021

mRNA vaccines shown to be 97% protective against COVID-19 in working-age population

Researchers in the United States have demonstrated the effectiveness of messenger RNA (mRNA)-based vaccination at protecting against infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among almost 47,000 healthcare workers.

7 Jun 2021

Single BioNTech/Pfizer vaccine dose reduces risk of COVID-19 by nearly 52%, matching clinical trial data

Data gathered from real-world vaccination programs following a single dose of Pfizer vaccine administration shows a reduction of 51.4% in infection risk and effectiveness of 54.4% against symptomatic coronavirus disease 2019 (COVID-19), matching clinical trial results.

7 Jun 2021

Methotrexate users fail to achieve adequate immune response to mRNA COVID-19 vaccines

Up to a third of patients taking methotrexate – a common treatment for immune mediated inflammatory conditions such as rheumatoid arthritis and psoriasis/psoriatic arthritis – failed to achieve an adequate immune response to mRNA COVID-19 vaccines in a small study accepted for publication in the journal Annals of the Rheumatic Diseases.

4 Jun 2021

Investigative journalist looks at independency of US and British vaccine advisory committees

Experts who sit on national vaccine advisory panels are asked to disclose any industry ties and other conflicts of interest. But an investigation published by The BMJ today finds that disclosure standards differ widely, often leaving the public in the dark.

4 Jun 2021

Study says COVID-19 vaccines passports will likely reduce inclination to accept vaccines

Now, a new study published on medRxiv* preprint server focuses on the quantitative evaluation of the impact of the implementation of vaccine passports for domestic and international travel.

4 Jun 2021

Researchers develop rapid antibody screening method for novel COVID-19 therapeutics development

New research undertaken by researchers in the USA describes two parallel but distinct in vivo approaches for the accelerated discovery of antibodies targeting SARS-CoV-2 spike protein.

3 Jun 2021

E484K mutation may confer immune evasion capability on UK variant of SARS-CoV-2

A new medRxiv* preprint reports the immunomodulatory effect of the E484K mutation newly acquired by the United Kingdom (U.K.) variant.

2 Jun 2021

Large-scale expansion of spike-reactive T cells feasible after COVID-19 vaccination

A new bioRxiv* preprint reports on the successful use of a protocol to expand SARS-CoV-2-reactive T-cells a thousand-fold.

2 Jun 2021

New vaccine candidate with RBD and N protein targets protects against SARS-CoV-2 in preclinical trials

A recent study published in the journal Science Advances, explores the immunization of RBD with the P2 epitope of tetanus toxoid, to enhance its immunogenicity, and also tests the benefit of N protein in the vaccine.

2 Jun 2021

Childhood vaccination rates in Texas have dropped steeply during COVID-19 pandemic

A team of researchers from universities in California and Texas has found immunization rates for children in Texas for a wide range of diseases, including polio and measles, have dropped steeply during the COVID-19 pandemic.

2 Jun 2021

Is COVID-19 vaccination in California equitable yet?

Researchers from the University of California, Davis recently conducted a short investigation to examine current vaccine equity and forecasts of vaccine coverage in California by June 15, 2020, in various scenarios.

1 Jun 2021

Report on the effectiveness of mRNA-1273 and BNT162b2 COVID-19 vaccines in Canada

The report has recently been published on the preprint server medRxiv* by Kwong et al. (May 28th, 2021) and focused on the Pfizer-BioNTech or Moderna vaccines, confirming the supposed greater efficacy in preventing infection or severe outcomes following the administration of two doses.

31 May 2021

A call to action to share 2 billion doses of COVAX in 2021

Countries that are advanced in their vaccination programmes are seeing cases of COVID-19 decline, hospitalizations decrease and early signs of some kind of normality resume.

31 May 2021

Identifying SARS-CoV-2 epitopes targeted by current vaccination could help improve future vaccines

Researchers in the United States have identified antibody-inducing epitopes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in individuals vaccinated against coronavirus disease 2019 (COVID-19) that could be used for future diagnostics, therapeutics, and vaccine design.

28 May 2021

Is a single Pfizer/BioNTech COVID-19 vaccine dose sufficient for individuals with prior SARS-CoV-2 infections?

A team of scientists from Spain has recently evaluated the immune responses induced by mRNA-based Pfizer/BioNTech coronavirus disease 2019 (COVID-19) vaccine in healthcare workers with or without a history of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

27 May 2021

New DNA COVID-19 vaccine proven effective in mice

A new study has shown that a new DNA-based COVID-19 vaccine successfully induced immunization against SARS-CoV-2 in mice and hamsters.

27 May 2021

Study shows more evidence that vaccines are safe for children, adults

A new study looking across a large body of research finds further evidence for the safety of vaccines that are Food and Drug Administration-approved and routinely recommended for children, adults and pregnant women.

27 May 2021

Moderna's COVID vaccine proves effective against South African variant in primates

Researchers in the United States have demonstrated the efficacy of Moderna’s coronavirus disease 2019 (COVID-19) vaccine at protecting against the South African B.1.351 variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in non-human primates.

26 May 2021

Immunization News and Research

Nanozymes to the rescue - potential role in fighting COVID-19

Repeated low-dose dose exposure to SARS-CoV-2 may protect against severe COVID-19

mRNA vaccines shown to be 97% protective against COVID-19 in working-age population

Single BioNTech/Pfizer vaccine dose reduces risk of COVID-19 by nearly 52%, matching clinical trial data

Methotrexate users fail to achieve adequate immune response to mRNA COVID-19 vaccines

Investigative journalist looks at independency of US and British vaccine advisory committees

Study says COVID-19 vaccines passports will likely reduce inclination to accept vaccines

Researchers develop rapid antibody screening method for novel COVID-19 therapeutics development

E484K mutation may confer immune evasion capability on UK variant of SARS-CoV-2

Large-scale expansion of spike-reactive T cells feasible after COVID-19 vaccination

New vaccine candidate with RBD and N protein targets protects against SARS-CoV-2 in preclinical trials

Childhood vaccination rates in Texas have dropped steeply during COVID-19 pandemic

Is COVID-19 vaccination in California equitable yet?

Report on the effectiveness of mRNA-1273 and BNT162b2 COVID-19 vaccines in Canada

A call to action to share 2 billion doses of COVAX in 2021

Identifying SARS-CoV-2 epitopes targeted by current vaccination could help improve future vaccines

Is a single Pfizer/BioNTech COVID-19 vaccine dose sufficient for individuals with prior SARS-CoV-2 infections?

New DNA COVID-19 vaccine proven effective in mice

Study shows more evidence that vaccines are safe for children, adults

Moderna's COVID vaccine proves effective against South African variant in primates

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