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Computational approach can help identify chemoresistant potential targets in cancer stem cells

In cancer, one of the most important features is the methylation of deoxycytosine to form 5-methylcytosine (5mC). DNA methylation is a process by which methyl groups (structural units of organic compounds consisting of three hydrogen atoms bonded to a carbon atom) are added to the DNA molecule.

30 Jan 2018

Viral replication process weak spot may help develop cure for infections

Researchers at the Morgridge Institute for Research believe they have identified a weak spot in the replication process of positive-strand RNA viruses, which could yield treatment for viral infections such as Zika, Polio, Chikungunya, Hepatitis C and even common cold viruses.

29 Jan 2018

Enzyme inhibitor and chemotherapy combination regresses glioblastoma

In animal experiments, a human-derived glioblastoma significantly regressed when treated with the combination of an experimental enzyme inhibitor and the standard glioblastoma chemotherapy drug, temozolomide.

24 Jan 2018

Scientists develop unique technique to map elasticity of cell components

Scientists at Université de Montréal have developed a unique technique to map, on a scale of milliseconds, the elasticity of the components inside a cell.

17 Jan 2018

Researchers use novel PET tracer to assess myelin damage in mouse models of MS

The loss or damage of myelin, a cellular sheath that surrounds and insulates nerves, is the hallmark of the immune-mediated neurological disorder multiple sclerosis.

12 Jan 2018

Unhealthy diet makes the body's defenses more aggressive in the long term

The immune system reacts similarly to a high fat and high-calorie diet as to a bacterial infection. This is shown by a recent study led by the University of Bonn.

11 Jan 2018

Discovery of key protein’s structure may help improve drug design

Scientists at The Scripps Research Institute have peered deep into the heart of a key protein used in drug design and discovered dynamic structural features that may lead to new ways to target diseases.

29 Dec 2017

Nanomedicine platform can guide doctors to remove tumors and kill malignant cells

Oregon State University scientists have developed a nanomedicine platform for cancer that can help doctors know which tissue to cut out as well as kill any malignant cells that can't be surgically removed.

21 Dec 2017

Silky webs of spiders may hold secrets to repairing our skeletons

Some secrets to repairing our skeletons might be found in the silky webs of spiders, according to recent experiments guided by supercomputers. Scientists involved say their results will help understand the details of osteoregeneration, or how bones repair themselves.

20 Dec 2017

Excessive copper in diabetes impedes ability to make new blood vessels

It's a metal we worry thieves will steal from our air conditioners or power lines, but inside our bodies too much copper can result in a much larger loss.

18 Dec 2017

Live-cell microscopy reveals internal forces that direct cell migration

Two new studies conducted at the Marine Biological Laboratory (MBL) indicate the way by which cells react to internal forces when they orient, gain traction, and migrate in a particular direction.

11 Dec 2017

Scientists discover how axons in developing visual system stabilize their connections

Scientists at Tokyo Tech have made an important discovery concerning the development of layer-specific axonal connections in the developing visual system of Drosophila flies.

8 Dec 2017

Scientists study behavior of Listeria monocytogenes during asymptomatic infection

Listeriosis is a disease caused by eating foods that have been contaminated by the Listeria monocytogenes bacterium.

1 Dec 2017

Tufts professor receives early-career award from AFOSR for ultra-high-resolution bio-imaging

Xiaocheng Jiang, assistant professor of biomedical engineering in the School of Engineering at Tufts University, has been awarded an early-career award from the Air Force Office of Scientific Research for his work developing graphene-based microfluidics for ultra-high-resolution, dynamic bio-imaging.

28 Nov 2017

New molecule demonstrates ability to block lymphoma growth

The prestigious scientific journal Clinical Cancer Research has published a study conducted by the research group led by Dr. Francesco Bertoni of the Institute of Oncology Research, that have tested a new molecule that demonstrates its ability to inhibit lymphoma growth.

28 Nov 2017