Neurodegenerative Diseases News and Research

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Small molecule drug can attenuate the triggers of neuroinflammation, preclinical study shows

Neuroinflammation can worsen outcomes in stroke, traumatic brain injury, or spinal cord injury, as well as accelerate neurodegenerative diseases like ALS, Parkinson's, or Alzheimer's. This suggests that limiting neuroinflammation may represent a promising new approach to treat neurological diseases and neuropathic pain that are driven by neuroinflammation.

24 Sep 2021

Neuroscientists discover how associative memories are formed

Has the scent of freshly baked chocolate chip cookies ever taken you back to afternoons at your grandmother's house? Has an old song ever brought back memories of a first date? The ability to remember relationships between unrelated items (an odor and a location, a song and an event) is known as associative memory.

23 Sep 2021

Immune cells in the brain join together to break down toxic proteins more quickly

To break down toxic proteins more quickly, immune cells in the brain can join together to form networks when needed. This is shown by a joint study of the University of Bonn, the German Center for Neurodegenerative Diseases, and the Institut François Jacob in France.

23 Sep 2021

Ryans make $25 million gift to name and endow the Robert J. Havey, MD, Institute for Global Health

Northwestern University Trustees and alumni Patrick G. Ryan and Shirley W. Ryan have made a $25 million gift to name and endow the Robert J. Havey, MD, Institute for Global Health at Northwestern University Feinberg School of Medicine.

22 Sep 2021

Study investigates if music can improve memory in people with Alzheimer's disease

The main goal of the study, named "The Mozart Effect and memory in patients with cognitive impairment (MEM-COG)", is to investigate whether music can be used to facilitate or enhance learning in those with mild cognitive impairment (MCI) or mild Alzheimer's disease (AD).

21 Sep 2021

Revival of the cell and gene therapy field opens new avenues for repairing the Parkinsonian brain

After several decades of pre-clinical development, cell- and gene-based therapies for Parkinson's disease (PD) are now actively being explored.

21 Sep 2021

Popular class of diabetes medications may be protective against glaucoma

A popular class of diabetes medications called GLP-1R agonists (Trulicity and Rybelsus) may also protect against glaucoma in diabetic patients, according to a new study led by researchers in the Scheie Eye Institute at the University of Pennsylvania's Perelman School of Medicine.

20 Sep 2021

Researchers identify key factor responsible for brain development during evolution

As humans, we have a large and intricately folded neocortex that accounts for many of our intellectual abilities and sets us apart from all other species

16 Sep 2021

Study finds possible direct connection between neurodegenerative diseases and the herpesvirus

A new study by researchers at University of Illinois Chicago suggests that when the protein optineurin, or OPTN, is present in cells it restricts the spread of HSV-1, the herpes simplex virus type 1.

13 Sep 2021

Study offers molecular insights into how toxic proteins are regulated in brain diseases

Rutgers researchers have discovered some of the first molecular insights into how toxic proteins are regulated in neurodegenerative diseases such as Alzheimer's and Parkinson's.

13 Sep 2021

NIH researchers develop a detailed cellular map of chronic MS lesions

Chronic lesions with inflamed rims, or "smoldering" plaques, in the brains of people with multiple sclerosis (MS) have been linked to more aggressive and disabling forms of the disease.

10 Sep 2021

Researchers decipher genetic mechanisms governing the speed of protein synthesis

In all eukaryotic organisms, genetic material is stored in the cell nucleus in the form of DNA. In order to be used, this DNA is first transcribed into messenger RNA in the cell cytoplasm, then translated into protein with the help of ribosomes, small machines capable of decoding messenger RNA to synthesise the appropriate proteins.

31 Aug 2021

NYU Tandon describes novel peptide with broad therapeutic potential to combat multiple diseases

NYU Tandon professors Mary Cowman and Jin Ryoun Kim recently published a paper describing a novel peptide with broad therapeutic potential to combat chronic inflammation in multiple diseases.

28 Aug 2021

Restoring DAXX protein levels may prevent misfolding of rogue proteins known to drive Alzheimer's

For the first time, Penn Medicine researchers showed how restoring levels of the protein DAXX and a large group of similar proteins prevents the misfolding of the rogue proteins known to drive Alzheimer's and other neurodegenerative diseases, as well as certain mutations that contribute to cancers.

26 Aug 2021

Atomic-level imaging of infectious prions reveals new therapeutic targets for untreatable diseases

The highest-ever resolution imaging of an infectious prion provides the first atomic-level data of how these abnormal proteins are assembled to cause fatal neurodegenerative diseases in people and animals - and how they can be potentially targeted by new therapies.

24 Aug 2021

Neurodegenerative Diseases News and Research

Small molecule drug can attenuate the triggers of neuroinflammation, preclinical study shows

Neuroscientists discover how associative memories are formed

Immune cells in the brain join together to break down toxic proteins more quickly

Ryans make $25 million gift to name and endow the Robert J. Havey, MD, Institute for Global Health

Study investigates if music can improve memory in people with Alzheimer's disease

Revival of the cell and gene therapy field opens new avenues for repairing the Parkinsonian brain

Popular class of diabetes medications may be protective against glaucoma

Researchers identify key factor responsible for brain development during evolution

Study finds possible direct connection between neurodegenerative diseases and the herpesvirus

Study offers molecular insights into how toxic proteins are regulated in brain diseases

NIH researchers develop a detailed cellular map of chronic MS lesions

Researchers decipher genetic mechanisms governing the speed of protein synthesis

NYU Tandon describes novel peptide with broad therapeutic potential to combat multiple diseases

Restoring DAXX protein levels may prevent misfolding of rogue proteins known to drive Alzheimer's

Atomic-level imaging of infectious prions reveals new therapeutic targets for untreatable diseases

Regular physical exercise modulates iron metabolism in Alzheimer’s mouse model

New mouse line reveals the state of protein balance in the mammalian brain for the first time

Research shines light on histamine as a potential key player in depression

Protein implicated in tumor growth may protect against neurodegenerative diseases

Having a good listener is associated with greater cognitive resilience

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