Sclerosis News and Research

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Cedars-Sinai researchers uncover the cause of UTI-induced delirium

Cedars-Sinai researchers have found that blocking the action of a protein called interleukin 6 (IL-6), part of the immune system, could resolve the delirium that often accompanies urinary tract infection (UTI) in elderly patients.

2 Dec 2021

NEI researchers identify unique population of B cells that tamps down the immune system

Researchers at the National Eye Institute (NEI) have identified, isolated, and characterized a unique population of B cells that tamps down the immune system, reducing chronic inflammation.

2 Dec 2021

Novel set of immune cells may have the opposite effect in multiple sclerosis, other brain conditions

A group of immune cells that normally protect against inflammation in the gastrointestinal tract may have the opposite effect in multiple sclerosis (MS) and other brain inflammation-related conditions, according to a new study by Weill Cornell Medicine and NewYork-Presbyterian researchers.

1 Dec 2021

Fast-tracked human stroke drug may also be a safe and powerful defense against dementia

A human stroke drug, fast-tracked by the Food and Drug Administration and soon entering Phase 3 clinical trials, shows intriguing signs that it might also be a safe and powerful defense against Alzheimer's and other forms of dementia.

1 Dec 2021

Novel anti-inflammatory drug target identified by CRISPR

In this interview, News-Medical speaks to Dr. Jeffrey Rathmell about his recent research into how metabolic pathways impact immune function.

1 Dec 2021

Teriflunomide tempers lesion growth in pediatric patients with multiple sclerosis

There are few treatment options for children with multiple sclerosis - a condition in which the immune system attacks the protective covering of nerves in the brain and spinal cord - and most therapies for the disease have not been tested in children.

30 Nov 2021

Brain scans of athletes exposed to repetitive head impacts show white matter hyperintensities

Certain markers of injury to the brain's white matter, called white matter hyperintensities, can be seen on brain scans.

25 Nov 2021

Experimental compound reduces diabetic complications in mice

An experimental compound reduced complications of type 1 and type 2 diabetes in mice—not by lowering blood sugar—but by countering its consequences of cell death, inflammation, and organ damage.

24 Nov 2021

People taking immunosuppressant produce weaker, shorter-lived antibodies after COVID-19 vaccination

People who received two doses of the Pfizer COVID-19 vaccine while on TNF inhibitors - a class of immunosuppressants used to treat rheumatoid arthritis and other autoimmune conditions - generated less powerful and shorter-lived antibodies against the virus that causes COVID-19 than healthy people and those on other kinds of immunosuppressants, according to a study by researchers at Washington University School of Medicine in St. Louis.

21 Nov 2021

Repurposed ALS drug could slow gradual brain cell loss in Niemann-Pick disease type C1

Riluzole, a drug approved to treat amyotrophic lateral sclerosis (ALS), a disease affecting nerve cells controlling movement, could slow the gradual loss of a particular brain cell that occurs in Niemann-Pick disease type C1 (NPC1), a rare genetic disorder affecting children and adolescents, suggests a study in mice by scientists at the National Institutes of Health.

20 Nov 2021

$10 million gift helps launch the Colton Center for Autoimmunity at Penn

Thanks to a generous $10 million gift from Stewart and Judy Colton, the Perelman School of Medicine at the University of Pennsylvania will continue to be on the leading edge of autoimmune research and care with the launch of the Colton Center for Autoimmunity at Penn.

18 Nov 2021

ALS also causes retinal alterations, study reveals

Amyotrophic lateral sclerosis (ALS), characterized by harm to brain neurons and to the spinal cord, also affects the tissue of the retina, according to a study headed up by Universidad Complutense de Madrid.

16 Nov 2021

Scientists identify new gene that contributes to type 1 diabetes progression

When the pro-inflammatory pair, a receptor called CCR2 and its ligand CCL-2, get together, it increases the risk of developing type 1 diabetes, scientists report.

16 Nov 2021

Study offers new insight into the role of tau proteins in ALS pathogenesis

A team led by investigators at Massachusetts General Hospital has shown that people living with amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, who carry a mutation in the C9orf72 gene exhibit elevated levels of tau and phosphorylated tau protein in the motor cortex region of the brain.

15 Nov 2021

Inflammatory chemicals involved in fat metabolism play key role in ALS, study shows

A new study using genetically engineered mice and human cell and tissue samples has added to evidence that higher levels of inflammatory chemicals involved in fat metabolism occur in people with amyotrophic lateral sclerosis (ALS), the neuromuscular disorder, also known as Lou Gehrig's disease.

15 Nov 2021

Your out-of-pocket health care costs need not be a mystery

If you've ever had a serious illness or cared for someone who has, you know how quickly the medical bills can pile up: from labs, radiology clinics, pharmacies, doctors, different departments within the same hospital — some of them in your insurance network, others not.

15 Nov 2021

Can COVID-19 vaccination lead to neurological complications?

A new review article discusses the neurological side effects due to SARS-CoV-2 vaccination.

14 Nov 2021

Identifying an important protein for motor coordination

News-Medical speaks to Professor Jorge Ruas about how he has identified an important protein involved in motor coordination.

10 Nov 2021

Study reveals the role of SPOP protein in an inherited form of ALS

The damaging effects of toxic proteins created in one inherited form of amyotrophic lateral sclerosis (ALS) are mediated by a protein called SPOP, according to a study published in the Proceedings of the National Academy of the Sciences.

8 Nov 2021

Prescription drug for multiple sclerosis improves memory in Alzheimer's mouse model

Losing memory is a hallmark of Alzheimer's, a symptom of the disease that depletes a patient's quality of life. Improving memory and slowing cognitive changes caused by the disease is an ongoing challenge for researchers seeking to develop novel therapies.

7 Nov 2021

Sclerosis News and Research

Cedars-Sinai researchers uncover the cause of UTI-induced delirium

NEI researchers identify unique population of B cells that tamps down the immune system

Novel set of immune cells may have the opposite effect in multiple sclerosis, other brain conditions

Fast-tracked human stroke drug may also be a safe and powerful defense against dementia

Novel anti-inflammatory drug target identified by CRISPR

Teriflunomide tempers lesion growth in pediatric patients with multiple sclerosis

Brain scans of athletes exposed to repetitive head impacts show white matter hyperintensities

Experimental compound reduces diabetic complications in mice

People taking immunosuppressant produce weaker, shorter-lived antibodies after COVID-19 vaccination

Repurposed ALS drug could slow gradual brain cell loss in Niemann-Pick disease type C1

$10 million gift helps launch the Colton Center for Autoimmunity at Penn

ALS also causes retinal alterations, study reveals

Scientists identify new gene that contributes to type 1 diabetes progression

Study offers new insight into the role of tau proteins in ALS pathogenesis

Inflammatory chemicals involved in fat metabolism play key role in ALS, study shows

Your out-of-pocket health care costs need not be a mystery

Can COVID-19 vaccination lead to neurological complications?

Identifying an important protein for motor coordination

Study reveals the role of SPOP protein in an inherited form of ALS

Prescription drug for multiple sclerosis improves memory in Alzheimer's mouse model

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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