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The phenolic composition, antioxidant capacity, and other functional properties of fresh and dried figs

Researchers explored the phytochemical contents and health benefits of consuming figs.

6 Jun 2023

How lipid metabolites in the gut aid in regulatory T-cell differentiation

Researchers describe the Treg-cell-inducing activity of lipid extracts from the feces of specific-pathogen-free mice.

6 Jun 2023

A SARS-CoV-2 spike-targeting bispecific T-cell engager strategy for controlling SARS-CoV-2 infection

Researchers described a novel strategy for controlling severe acute respiratory syndrome coronavirus 2.

5 Jun 2023

Multiple sclerosis: Immune cell invasion enabled by blood-brain barrier breakdown

Blood-brain barrier breakdown in multiple sclerosis leads to immune cell infiltration into the central nervous system. Antigen presentation at the barrier promotes CD8+ T cell entry, triggering focal breakdown and hindering their invasion.

4 Jun 2023

Researchers characterize a unique molecular mechanism of early stages of programmed cell death

Researchers have for the first time characterized a unique molecular mechanism of the early stages of programmed cell death or apoptosis, a process which plays a crucial role in prevention of cancer.

2 Jun 2023

MatTek and AIM Biotech Partner on Advanced 3D Tissue Culture Organ-on-a-Chip Systems

Today, MatTek Life Sciences and AIM Biotech announced a strategic partnership through which the AIM Biotech portfolio will be available for sale through MatTek.

From MatTek Corporation 2 Jun 2023

Study shows humans may have evolved a spring-like arch to help us walk on two feet

A recent study hypothesized that the arch recoils to propel the COM, which affects the ankle posture.

2 Jun 2023

Study suggests licorice-derived liquiritigenin has breast cancer prevention potential for high-risk postmenopausal women

Researchers evaluated the potential of three licorice (Glycyrrhiza) species, i.e., G. glabra (GG), G. uralensis (GU), and G. infata (GI), and hops (Humulus lupulus), and their main bioactive polyphenols, to prevent breast malignancy.

1 Jun 2023

New insight into how click chemistry EV/peptide/chemokine nanomissiles repair CNS injuries

This new article publication from Acta Pharmaceutica Sinica B, discusses click chemistry extracellular vesicle/peptide/chemokine nanocarriers for treating central nervous system injuries.

31 May 2023

Lipid-degrading enzyme, fatty acid amide hydrolase is a predictor of long-term survival in patients with breast cancer

Scientists have identified a lipid-degrading enzyme as a prognostic biomarker for luminal breast cancer.

31 May 2023

Study shows impacts of ASO-based MALAT1-inhibition on MAPK-pathway gene regulation in melanoma

A new research paper was published in Oncotarget's Volume 14 on May 26, 2023, entitled, "Deconstructing the role of MALAT1 in MAPK-signaling in melanoma: insights from antisense oligonucleotide treatment."

30 May 2023

Novel technology enhances potency and breadth of vaccine-induced responses through antigen presentation

Novel EABR technology enhances potency and breadth of vaccine-induced responses through antigen presentation.

30 May 2023

Novel assay for identifying individuals with synucleinopathies using serum samples

Synucleinopathies are a group of neurodegenerative diseases caused by the abnormal accumulation α-synuclein, a protein normally found in the brain and neurons. Incorrect folding of α-synuclein leads to formation of 'seeds', which attract more α-synuclein proteins to form larger clumps.

29 May 2023

Novel endoscopic imaging system design could accelerate the adoption of multi-tracer FGS

For patients with solid cancers, endoscopic surgery is one of the primary treatment options to remove tumors. However, there is a high risk of cancer recurrence if even a small number of cancerous cells are left behind after surgical resection.

26 May 2023

Using nanoparticles and magnetic field to guide immunotherapy cells

A novel ideal proposed by European researchers would guide immunotherapy cells to where they are needed most.

26 May 2023

The potential clinical benefit of the Multabody platform as a therapeutic for SARS-CoV-2

The potential clinical benefit of the Multabody platform as a therapeutic for SARS-CoV-2.

26 May 2023

T-cell-inducing mRNA COVID-19 vaccine improves effectiveness

Researchers develop a lipid nanoparticle-formulated mRNA-based antigen encoding three SARS-CoV-2 peptides derived from non-structural proteins.

25 May 2023

Bridging the Gap between Academia and Industry: The Power of Collaboration in Life Sciences

In this behind-the-scenes interview, we speak to Dr. Sinead Knight, chair of SLAS Europe 2023, about this years programme, highlighting the key topics and speakers.

From Society for Laboratory Automation and Screening (SLAS) 25 May 2023

COVID-19 'bites the apple': Abdominal obesity ignites cytokine storm

Abdominal obesity increases the risk of severe COVID-19 and mortality due to heightened inflammatory responses, according to a study on Japanese patients and a murine COVID-19 model. Blocking inflammatory cytokines and preventing obesity may improve survival rates.

24 May 2023

Gut check: Our microbiome's vitamin factory could redefine personal health

Research highlights the crucial role of vitamins in metabolic and regulatory processes. It explores the microbial contribution of essential vitamins, such as vitamin K and B-group vitamins, in the gastrointestinal tract, emphasizing their impact on human health and the gut microbiome.

23 May 2023

in vivo News and Research

The phenolic composition, antioxidant capacity, and other functional properties of fresh and dried figs

How lipid metabolites in the gut aid in regulatory T-cell differentiation

A SARS-CoV-2 spike-targeting bispecific T-cell engager strategy for controlling SARS-CoV-2 infection

Multiple sclerosis: Immune cell invasion enabled by blood-brain barrier breakdown

Researchers characterize a unique molecular mechanism of early stages of programmed cell death

MatTek and AIM Biotech Partner on Advanced 3D Tissue Culture Organ-on-a-Chip Systems

Study shows humans may have evolved a spring-like arch to help us walk on two feet

Study suggests licorice-derived liquiritigenin has breast cancer prevention potential for high-risk postmenopausal women

New insight into how click chemistry EV/peptide/chemokine nanomissiles repair CNS injuries

Lipid-degrading enzyme, fatty acid amide hydrolase is a predictor of long-term survival in patients with breast cancer

Study shows impacts of ASO-based MALAT1-inhibition on MAPK-pathway gene regulation in melanoma

Novel technology enhances potency and breadth of vaccine-induced responses through antigen presentation

Novel assay for identifying individuals with synucleinopathies using serum samples

Novel endoscopic imaging system design could accelerate the adoption of multi-tracer FGS

Using nanoparticles and magnetic field to guide immunotherapy cells

The potential clinical benefit of the Multabody platform as a therapeutic for SARS-CoV-2

T-cell-inducing mRNA COVID-19 vaccine improves effectiveness

Bridging the Gap between Academia and Industry: The Power of Collaboration in Life Sciences

COVID-19 'bites the apple': Abdominal obesity ignites cytokine storm

Gut check: Our microbiome's vitamin factory could redefine personal health

eBook: Using iPSCs models for human disease research and drug discovery eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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