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Food preservative nisin: A gut game changer that safely alters microbiome composition

Nisin, a powerful bacteriocin, influences the gut microbiota and its functionality by modulating the abundance of specific bacterial groups and altering short-chain fatty acid synthesis.

18 May 2023

How estrogens and progesterone present in human milk impact infants' health

Review examines the presence of estrogens and progesterone in human milk and their potential impact on infant growth and health. It explores factors influencing hormone levels and provides insights for effective intervention strategies.

18 May 2023

Researchers identify a major stem cell variant in lungs of patients with idiopathic pulmonary fibrosis

A pair of internationally renowned stem cell cloning experts at the University of Houston is reporting their findings of variant cells in the lungs of patients with Idiopathic Pulmonary Fibrosis (IPF) which likely represent key targets in any future therapy for the condition.

17 May 2023

Novel antibodies target human receptors to neutralize SARS-CoV-2 variants and future sarbecoviruses

Researchers generated six human monoclonal antibodies that prevented infection.

17 May 2023

Machine learning reveals sex-specific Alzheimer's risk genes

Research explores sex-specific gene associations in Alzheimer's disease using a machine-learning approach. It reveals immune response pathways in both sexes and stress-response pathways in males, highlighting potential biomarkers and therapeutic targets for personalized treatments.

16 May 2023

Molecular mechanism behind a DNA repair pathway revealed

A new study adds to an emerging, radically new picture of how bacterial cells continually repair faulty sections of their DNA.

16 May 2023

HER2-TPMC proves to be a reasonable alternative for HER2-positive cancer chemotherapeutics

Announcing a new article publication for BIO Integration journal. Antibody-drug conjugates (ADCs) have the following advantages: target specificity; wide therapeutic index; and prolonged circulation half-life.

15 May 2023

Study shows two distinct types of cerebellar neurons differentially regulate motor and social behaviors

The cerebellum, a major part of the hindbrain in all vertebrates, is important for motor coordination, language acquisition, and regulating social and emotional behaviors.

15 May 2023

Phase 1 clinical trial of CAR-NKT cell therapy shows promising results in neuroblastoma patients

Researchers at Baylor College of Medicine/Texas Children's Cancer Center and collaborating institutions report interim results from a first-in-human phase 1 clinical trial evaluating the safety, antitumor activity and immunological characteristics of a genetically engineered natural killer T (NKT) cell immunotherapy for neuroblastoma, a childhood tumor that most commonly arises in the adrenal gland.

15 May 2023

Humanized mouse model for rare genetic disease developed for the first time

Mice with a defected human gene responsible for a rare genetic disease, called congenital adrenal hyperplasia, have been developed for the first time.

15 May 2023

Nanoparticles take aim at COVID-19 with lysosome-targeted delivery

Researchers discuss the use of endo-lysosome-targeted nanoparticles for delivering antiviral therapy to treat coronavirus infections.

15 May 2023

Novel ingestible device enables non-invasive profiling of the gut microbiome, proteome, and metabolome

Researchers developed an ingestible device to collect samples from the human intestine.

12 May 2023

How eating mushrooms may lower blood pressure levels

Scientists review the potential of edible mushrooms as functional foods in improving cardiovascular function and ameliorating hypertension.

11 May 2023

New CRISPR genome-editing technology helps scientists to explore many cancer-linked mutations

Genomic studies of cancer patients have revealed thousands of mutations linked to tumor development.

11 May 2023

Evaluating the effect of resveratrol-enriched bread in preventing early type 2 diabetes cardiomyopathy in vivo

Researchers examined the effects of resveratrol-enriched bread on a diabetes model.

11 May 2023

Unlocking the secrets of Omicron: study reveals how unique spike mutations enable enhanced infectivity and resistance to immune barrier

Researchers reported the increased transmissibility of the severe acute respiratory syndrome coronavirus 2.

11 May 2023

New toolkit enables in-vivo cross-linking of protein complexes in live cells

As the executor of life activities, proteins exert their specific biological functions through interactions such as forming protein complexes.

9 May 2023

First CRISPR-armed phage therapeutic can specifically target and remove E. coli in the human gut

SNIPR Biome ApS ("SNIPR"), the company pioneering CRISPR-based microbial gene therapy, announces today that Nature Biotechnology has published research findings from its preclinical work on SNIPR001, the first CRISPR-armed phage therapeutic developed to specifically target and remove E. coli, including antibiotic-resistant strains, in the human gastrointestinal tract.

8 May 2023

Plant-based dairy alternatives in the human diet

Researchers explored the association between plant-based dairy alternatives (PBDAs) and the human diet.

5 May 2023

Study finds a pharmacological-based approach to revert immune escape of breast cancer cells

Freiburg researchers discover a mechanism by which cancer cells escape the immune system.

4 May 2023

in vivo News and Research

Food preservative nisin: A gut game changer that safely alters microbiome composition

How estrogens and progesterone present in human milk impact infants' health

Researchers identify a major stem cell variant in lungs of patients with idiopathic pulmonary fibrosis

Novel antibodies target human receptors to neutralize SARS-CoV-2 variants and future sarbecoviruses

Machine learning reveals sex-specific Alzheimer's risk genes

Molecular mechanism behind a DNA repair pathway revealed

HER2-TPMC proves to be a reasonable alternative for HER2-positive cancer chemotherapeutics

Study shows two distinct types of cerebellar neurons differentially regulate motor and social behaviors

Phase 1 clinical trial of CAR-NKT cell therapy shows promising results in neuroblastoma patients

Humanized mouse model for rare genetic disease developed for the first time

Nanoparticles take aim at COVID-19 with lysosome-targeted delivery

Novel ingestible device enables non-invasive profiling of the gut microbiome, proteome, and metabolome

How eating mushrooms may lower blood pressure levels

New CRISPR genome-editing technology helps scientists to explore many cancer-linked mutations

Evaluating the effect of resveratrol-enriched bread in preventing early type 2 diabetes cardiomyopathy in vivo

Unlocking the secrets of Omicron: study reveals how unique spike mutations enable enhanced infectivity and resistance to immune barrier

New toolkit enables in-vivo cross-linking of protein complexes in live cells

First CRISPR-armed phage therapeutic can specifically target and remove E. coli in the human gut

Plant-based dairy alternatives in the human diet

Study finds a pharmacological-based approach to revert immune escape of breast cancer cells

eBook: Using iPSCs models for human disease research and drug discovery eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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