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CHP Canada commends launch of consultations on proposed consumer health products

Consumer Health Products Canada (CHP Canada) applauds federal Health Minister Rona Ambrose for beginning consultations on a proposed consumer health products framework.

29 Nov 2014

New active substance effectively combats Philadelphia chromosome-positive leukaemia

Haematologists from Goethe University Frankfurt, working with a Russian pharmaceutical company, have developed a new active substance that effectively combats the most aggressive forms of Philadelphia chromosome-positive leukaemia.

29 Nov 2014

Researchers investigate FDA influence for improving pivotal drug studies

An examination of the potential interaction between pharmaceutical companies and the U.S. Food and Drug Administration (FDA) to discuss future studies finds that one-quarter of recent new drug approvals occurred without any meeting, and when such meetings occurred, pharmaceutical companies did not comply with one-quarter of the recommendations made by the FDA regarding study design or primary outcome, according to a study in the November 26 issue of JAMA.

28 Nov 2014

Study provides proof of concept for developing antibodies against human pathogens

Scientists investigating the potentially deadly hantavirus have used a novel approach to developing protective antibodies against it. Their work, published in today's online edition of Science Translational Medicine, provides proof of concept for producing antibodies against a broad range of human pathogens.

28 Nov 2014

Early intervention benefits may not stay the course in psychosis

Most of the benefits of a specialised early intervention for psychosis have disappeared by 8 years after its completion, shows follow-up of the OPUS trial.

27 Nov 2014

Better evidence needed for relationship between exercise and COPD

Researchers call for high-quality studies investigating the relationship between physical activity and chronic obstructive pulmonary disease after their systematic review found the level of evidence to be poor.

27 Nov 2014

Hovione submits first IND Application with FDA for minocycline gel

Hovione announced today it has filed its first Investigational New Drug (IND) Application with the U.S. Food and Drug Administration. This event represents a milestone in Hovione's strategy of developing improved drug delivery options for established drugs.

27 Nov 2014

Ebola vaccine shows promising results in human trial

An experimental vaccine against the Ebola virus has proved effective and well-tolerated in the first human trial of a candidate Ebola drug.

27 Nov 2014

Plymouth professor awarded grant to find effective treatment for patients with mantle cell lymphoma

Professor Simon Rule, Professor in Haematology at Plymouth University Peninsula Schools of Medicine and Dentistry and Consultant Haematologist at Plymouth Hospitals NHS Trust, has been awarded a significant grant by Cancer Research UK to carry out a research study into the treatment of older patients with mantle cell lymphoma.

27 Nov 2014

HIV drugs could be harnessed to treat leading cause of blindness

An established class of drugs, traditionally used to control HIV/AIDS infections, could soon be harnessed to treat the leading cause of blindness and visual impairment in the UK, for which currently there exists no cure.

27 Nov 2014

FDA issues Complete Response letter for Avanir’s AVP-825 NDA

Avanir Pharmaceuticals, Inc. today announced that the U.S. Food and Drug Administration (FDA) has issued a Complete Response letter to its New Drug Application (NDA) for AVP-825.

27 Nov 2014

Gothenburg study shows epilepsy surgery is a low-risk procedure

A study at Sahlgrenska Academy, University of Gothenburg, has found that epilepsy surgery is a safe, effective and low-risk procedure. Nevertheless, few Swedes have the operation, and those who are interested may have to wait a long time for presurgical counseling.

27 Nov 2014

Researchers use EHRs to uncover hidden drug benefits

With research and development costs for many drugs reaching well into the billions, pharmaceutical companies want more than ever to determine whether their drugs already at market have any hidden therapeutic benefits that could warrant putting additional indications on the label and increase production.

27 Nov 2014

Cimetidine drug could be one of many common over-the-counter medicines to treat cancer

A popular indigestion medication can increase survival in colorectal cancer, according to research published in ecancermedicalscience. But in fact, scientists have studied this for years - and a group of cancer advocates want to know why this research isn't more widely used.

27 Nov 2014

Minimally invasive surgeries successfully performed at Policlinico Gemelli in Rome with ALF-X system

It's called ALF-X and it's the innovative robotic surgical system being used by gynaecological surgeons at the A. Gemelli University Polyclinic in Rome, which has been in operation in the surgical field for a year in the Department for the Protection of Health of Women, Newborns, Children and Adolescents, directed by professor Giovanni Scambia.

26 Nov 2014

Researchers demonstrate efficacy of Bozepinib drug against cancerogenic stem cells

An Andalusian team of researchers led by the University of Granada has demonstrated the efficacy of a new drug against cancerogenic stem cells, which cause the onset and development of cancer, of relapse after chemotherapy and metastasis. This drug, called Bozepinib, has proved to be effective in tests with mice.

26 Nov 2014

Promethera Biosciences completes €25.33 million ($31.4 million) Series C fundraising

Promethera Biosciences, a Belgian biotechnology company developing Promethera HepaStem, a cell-based therapy for the treatment of in-born errors of metabolism and acquired liver diseases, today announces the completion of its Series C fundraising round. The company has raised €25.33 million ($31.4 million), including €20.33 million in capital.

26 Nov 2014

New NIH funding to help researchers develop drug delivery system to prevent HIV infection in women

The University of Texas Medical Branch is part of a collaboration led by the Oak Crest Institute of Science that received a $20 million grant from the National Institutes of Health to develop a novel intravaginal ring capable of delivering powerful antiretroviral drugs to prevent the spread of sexually transmitted HIV in women. The total award to UTMB is approximately $2.5 million.

26 Nov 2014

Janssen submits YONDELIS NDA for treatment of advanced soft tissue sarcoma

PharmaMar announces that Janssen Research & Development, LLC has submitted a New Drug Application (NDA) for YONDELIS (trabectedin) to the U.S. Food and Drug Administration for the treatment of patients with advanced soft tissue sarcoma (STS), including liposarcoma and leiomyosarcoma subtypes, who have received prior chemotherapy including an anthracycline.

26 Nov 2014

Automated biospecimen thawing: an interview with Dr Rolf Ehrhardt, CEO of BioCision

Surprisingly, even with decades of cryopreservation research, little progress has been made in the way frozen biospecimens are thawed. It’s still very common for researchers and clinicians to thaw cells and other frozen biological samples in a variety of manual ways ...

25 Nov 2014

Efficacy News and Research

CHP Canada commends launch of consultations on proposed consumer health products

New active substance effectively combats Philadelphia chromosome-positive leukaemia

Researchers investigate FDA influence for improving pivotal drug studies

Study provides proof of concept for developing antibodies against human pathogens

Early intervention benefits may not stay the course in psychosis

Better evidence needed for relationship between exercise and COPD

Hovione submits first IND Application with FDA for minocycline gel

Ebola vaccine shows promising results in human trial

Plymouth professor awarded grant to find effective treatment for patients with mantle cell lymphoma

HIV drugs could be harnessed to treat leading cause of blindness

FDA issues Complete Response letter for Avanir’s AVP-825 NDA

Gothenburg study shows epilepsy surgery is a low-risk procedure

Researchers use EHRs to uncover hidden drug benefits

Cimetidine drug could be one of many common over-the-counter medicines to treat cancer

Minimally invasive surgeries successfully performed at Policlinico Gemelli in Rome with ALF-X system

Researchers demonstrate efficacy of Bozepinib drug against cancerogenic stem cells

Promethera Biosciences completes €25.33 million ($31.4 million) Series C fundraising

New NIH funding to help researchers develop drug delivery system to prevent HIV infection in women

Janssen submits YONDELIS NDA for treatment of advanced soft tissue sarcoma

Automated biospecimen thawing: an interview with Dr Rolf Ehrhardt, CEO of BioCision

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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