Protein C News and Research

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HP1a is a key epigenetic regulator that maintains chromosome integrity

The information of the human genome is encoded by approximately 3 billion DNA base pairs and packaged into 23 pairs of chromosomes.

16 Apr 2021

Researchers probe intriguing interaction between sugars and the SARS-CoV-2 spike protein

A new study posted to the bioRxiv preprint server focuses on a novel formulation of magnetization or saturation transfer. This method is developed by amalgamating theoretical and computational approaches based on a Bayesian deconvolution algorithm, which helps obtain data more accurately and determine the ligand-protein interaction.

16 Apr 2021

Targeting brain protein may lead to new therapeutic approaches for neurodegenerative disorders

Neurological disorders are the number one cause of disability in the world, leading to seven million deaths each year. Yet few treatments exist for these diseases, which progressively diminish a person's ability to move and think.

16 Apr 2021

Novel gene mutations may help identify patients with a specific form of muscular dystrophy

New research from the University of Minnesota Medical School found mutations in a novel gene that may help identify patients with a specific form of muscular dystrophy.

16 Apr 2021

Cell receptor neuropilin-1 offers a promising anti-tumor strategy

Cancer is an insidious disease that, despite being around for centuries, is still very difficult to diagnose and treat. Thus, cancer has been the focus much research in the biomedical fields.

16 Apr 2021

Modeling study suggests how different SARS-CoV-2 mutations prevent antibody binding

This suggests a cocktail of antibodies will work better at neutralizing the virus than a single antibody alone. In a study published in the bioRxiv* preprint server, researchers report the structure of binding complexes of the different classes of antibodies to the spike RBD using computational modeling, which may also help explain how the virus generates escape mutations.

16 Apr 2021

More SARS-CoV-2 variants have emerged from immunocompromised hosts, shows research

A number of SARS-CoV-2 variants have emerged from immunocompromised hosts, research has identified. It is thought that variants of concern - including B.1.1.7, a variant first identified in Kent - were a result of long-term infection in people with a weakened immune system.

16 Apr 2021

Researchers invent new technique to measure the speed of fibril growth

Amyloid fibrils are deposits of proteins in the body that join together to form microscopic fibres. Their formation has been linked to many serious human diseases including Alzheimer's, Parkinson's and Type 2 diabetes.

16 Apr 2021

Single dose of Oxford–AstraZeneca COVID vaccine shown to be more immunogenic than natural infection

By investigating antibody and T cell responses to a single dose of the Oxford–AstraZeneca COVID-19 vaccine, researchers from Sri Lanka and the United Kingdom have found that more than 90% of vaccinated individuals produced an adequate amount of antibodies after receiving only one dose of the vaccine – irrespective of their age and gender.

16 Apr 2021

Scientists illuminate how some antibodies can effectively disable ebolaviruses

Some survivors of ebolavirus outbreaks make antibodies that can broadly neutralize these viruses--and now, scientists at Scripps Research have illuminated how these antibodies can disable the viruses so effectively.

16 Apr 2021

COVID-19 vaccine INO-4800 shows efficacy against SARS-CoV-2 variants

Researchers in the United States have demonstrated the efficacy of the vaccine INO-4800 against variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

15 Apr 2021

Japanese–European scientists detect novel genetic mitochondrial disorder

The list of known genetic mitochondrial disorders is ever-growing, and ongoing research continues to identify new disorders in this category.

15 Apr 2021

CityU researchers identify super-enhancers that stimulate the activity of breast cancer genes

Triple-negative breast cancer (TNBC) is an aggressive type of breast cancer with a high fatality rate. Currently, chemotherapy is the major treatment option, but the clinical result is unsatisfactory.

15 Apr 2021

New machine learning method for designing more effective antibody drugs

Antibodies are not only produced by our immune cells to fight viruses and other pathogens in the body. For a few decades now, medicine has also been using antibodies produced by biotechnology as drugs.

15 Apr 2021

CHOP researchers identify key target responsible for treatment failure in patients with hemophilia A

Researchers at Children's Hospital of Philadelphia have identified a key target that may be responsible for treatment failure in about 30% of patients with hemophilia A.

15 Apr 2021

Researchers develop “Nano-Glue” with therapeutic potential against SARS-CoV-2

In a recent study, researchers target the electropositive receptor-binding domain (RBD) on the SARS-CoV-2 spike protein with the abundant β-sheet structure as a novel COVID-19 therapeutic drug design.

15 Apr 2021

Researchers unravel the molecular basis of how Mtb uses and transports an essential sugar

Tuberculosis is a devastating disease that claims over 1.5 million lives each year. The increase in TB cases that are resistant to the current antibiotics means that novel drugs to kill Mycobacterium tuberculosis (Mtb) are urgently needed.

15 Apr 2021

Doctors warn about the potential cardiovascular dangers of energy drink consumption

Heavy energy drink consumption may be linked to heart failure, doctors have warned in the journal BMJ Case Reports after treating a 21 year old, who had regularly drunk 4 such cans every day for around 2 years.

15 Apr 2021

DNAJC9 protein plays a key role in safeguarding histones, shows study

In the cell nucleus histones play a crucial role packaging DNA into chromatin. Histones are however very sticky to both DNA and RNA, so to ensure they are transported to the cell nucleus after synthesis and bind to the right portion of DNA to organize the chromatin, they are guarded by complexes of histone chaperones.

15 Apr 2021

Self-assembling nanofibers can help limit damage caused by inflammatory diseases

Biomedical engineers at Duke University have developed a self-assembling nanomaterial that can help limit damage caused by inflammatory diseases by activating key cells in the immune system.

15 Apr 2021

Protein C News and Research

HP1a is a key epigenetic regulator that maintains chromosome integrity

Researchers probe intriguing interaction between sugars and the SARS-CoV-2 spike protein

Targeting brain protein may lead to new therapeutic approaches for neurodegenerative disorders

Novel gene mutations may help identify patients with a specific form of muscular dystrophy

Cell receptor neuropilin-1 offers a promising anti-tumor strategy

Modeling study suggests how different SARS-CoV-2 mutations prevent antibody binding

More SARS-CoV-2 variants have emerged from immunocompromised hosts, shows research

Researchers invent new technique to measure the speed of fibril growth

Single dose of Oxford–AstraZeneca COVID vaccine shown to be more immunogenic than natural infection

Scientists illuminate how some antibodies can effectively disable ebolaviruses

COVID-19 vaccine INO-4800 shows efficacy against SARS-CoV-2 variants

Japanese–European scientists detect novel genetic mitochondrial disorder

CityU researchers identify super-enhancers that stimulate the activity of breast cancer genes

New machine learning method for designing more effective antibody drugs

CHOP researchers identify key target responsible for treatment failure in patients with hemophilia A

Researchers develop “Nano-Glue” with therapeutic potential against SARS-CoV-2

Researchers unravel the molecular basis of how Mtb uses and transports an essential sugar

Doctors warn about the potential cardiovascular dangers of energy drink consumption

DNAJC9 protein plays a key role in safeguarding histones, shows study

Self-assembling nanofibers can help limit damage caused by inflammatory diseases

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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