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Researchers awarded $25 million NIH grant to study critical limb ischemia treatment

A team of researchers from Brigham and Women's Hospital, Boston Medical Center and Massachusetts General Hospital has been awarded $25 million by the National Institutes of Health to conduct a four-year, randomized clinical trial-the BEST-CLI Trial (Best Endovascular versus Best Surgical Therapy in Patients with Critical Limb Ischemia). The trial will compare traditional bypass surgery with the less invasive alternative of endovascular treatment for patients with critical limb ischemia.

11 Dec 2013

Researchers find decreased energy metabolism in heart cells as significant independent risk factor

Johns Hopkins researchers have identified a new way to predict which heart failure patients are likely to see their condition get worse and which ones have a better prognosis. Their study is one of the first to show that energy metabolism within the heart, measured using a noninvasive magnetic resonance imaging test, is a significant predictor of clinical outcomes, independent of a patient's symptoms or the strength of the heart's ability to pump blood, known as the ejection fraction.

11 Dec 2013

Early tumor shrinkage predicts targeted therapy efficacy in RCC

Early tumor shrinkage in patients with metastatic renal cell carcinoma following vascular endothelial growth factor-targeted therapy may herald good long-term survival, research shows.

11 Dec 2013

Shared genetic risk for bipolar and alcohol use disorders

Shared genetic factors affect the risk for bipolar disorder and alcohol use disorder, suggesting a common underlying biology, research shows.

11 Dec 2013

Early antibiotic use linked to asthma, not atopy

Research from the UK has found a “robust and dose-dependent” association between antibiotic use in the first 2 years of life and subsequent asthma at the age of 7 and a half years.

11 Dec 2013

Schizophrenia treatment responses follow distinct trajectories

The positive and negative symptoms of schizophrenia generally change in parallel with each other, shows research, supporting the notion that the different symptom domains of the condition have a shared underlying pathology.

11 Dec 2013

HIV stigma: an interview with Dr. Vargas-Jackson, M.D. Howard University Hospital

Stigma has been defined as a social opportunistic disease that attaches to many illnesses and increases morbidity and mortality rates. Stigma is the shame or disgrace attached to illnesses and diseases regarded as socially unacceptable.

11 Dec 2013

AlzeCure deploys Vortex tool to develop novel therapies for Alzheimer's disease

Dotmatics, a leading provider of scientific informatics solutions and services to the pharmaceutical and biotechnology industries, announced today that the research foundation AlzeCure, has deployed and integrated the data visualization and analysis tool Vortex. AlzeCure is a novel innovative drug discovery unit that will use Vortex to help in the quest to discover and develop novel therapies for the treatment of Alzheimer's disease and other neurodegenerative disorders.

11 Dec 2013

Queen's University heads key European study to find new treatments for bowel cancer

Queen's University has announced it is to lead a €6 million European study to find new treatments for bowel cancer.

11 Dec 2013

Father's diet before conception plays crucial role in health of offspring

Mothers get all the attention. But a study led by McGill researcher Sarah Kimmins suggests that the father's diet before conception may play an equally important role in the health of their offspring. It also raises concerns about the long-term effects of current Western diets and of food insecurity.

11 Dec 2013

Valuable new approach to cancer treatment

Since the discovery of penicillin, fungi have been a nearly inexhaustible source for the discovery of new drugs. “Crowdsourcing”, the cooperation of a large number of interested nonscientists, has helped to find a new fungus from which American researchers have now isolated and characterized an unusual metabolite with interesting antitumor activity.

11 Dec 2013

Study set to shed new light on one of Australia's most debilitating illnesses

With Christmas just around the corner, a time where some people can face emotional difficulties, stress or isolation, a University of Sydney study is set to shed new light on one of Australia's most debilitating illnesses.

11 Dec 2013

Results-Based Financing for Health can get 20% more health care with same funds

Countries and major donors are changing the way they finance maternal and child, malaria, tuberculosis and HIV/AIDS health programs in low-income countries to increase their impact.

11 Dec 2013

Prana Biotechnology provides update on IMAGINE PBT2 trial for Alzheimer’s disease

Prana Biotechnology, a developer of best-in-class treatments for neurodegenerative disease, today provided an update of its IMAGINE Alzheimer’s Disease Extension trial.

11 Dec 2013

Detectable blood viral load increases prevalence of heart disease

HIV causes structural heart disease according to research presented at EuroEcho-Imaging 2013 by Dr Nieves Montoro from Madrid, Spain. The findings support the introduction of cardiovascular screening in all HIV patients, particularly those with a positive blood viral load.

11 Dec 2013

Sites selected by early human ancestors were abundant in nutrient-rich food, shows research

Research led by the University of Southampton has found that early humans were driven by a need for nutrient-rich food to select 'special places' in northern Europe as their main habitat.

11 Dec 2013

EPSRC donates £5 million for dementia research

Health ministers from the G8 nations will meet in London today (11 December) to discuss the global health challenge posed by dementia. The summit aims to develop co-ordinated global action on dementia. One area of focus at the summit is preventing and delaying dementia.

11 Dec 2013

Motivated forgetting often occurs when people feel the most threatened, says study

After a traumatic experience, the details we remember surrounding the event are sometimes foggy. According to a new study in the Journal of Consumer Research, consumers remember the least when they feel the most threatened.

11 Dec 2013

State highlights: Health care price data and transparency in N.Y. and Calif.; states shift tobacco settlement funds away from prevention

Just how expensive is your hospital? In New York, the answer may lie in a trove of hospital cost data newly posted online by the State Health Department. As part of an effort to make health care pricing more transparent, the state is naming hospitals and listing their median charges and costs for 1,400 conditions and procedures from 2009 to 2011.

11 Dec 2013

New family of drugs may help combat childhood tumor

St. Jude Children's Research Hospital-Washington University Pediatric Cancer Genome Project study identifies drugs that enhance oxidative stress as possible weapon against most common pediatric soft tissue tumor

11 Dec 2013

Research News and Research

Researchers awarded $25 million NIH grant to study critical limb ischemia treatment

Researchers find decreased energy metabolism in heart cells as significant independent risk factor

Early tumor shrinkage predicts targeted therapy efficacy in RCC

Shared genetic risk for bipolar and alcohol use disorders

Early antibiotic use linked to asthma, not atopy

Schizophrenia treatment responses follow distinct trajectories

HIV stigma: an interview with Dr. Vargas-Jackson, M.D. Howard University Hospital

AlzeCure deploys Vortex tool to develop novel therapies for Alzheimer's disease

Queen's University heads key European study to find new treatments for bowel cancer

Father's diet before conception plays crucial role in health of offspring

Valuable new approach to cancer treatment

Study set to shed new light on one of Australia's most debilitating illnesses

Results-Based Financing for Health can get 20% more health care with same funds

Prana Biotechnology provides update on IMAGINE PBT2 trial for Alzheimer’s disease

Detectable blood viral load increases prevalence of heart disease

Sites selected by early human ancestors were abundant in nutrient-rich food, shows research

EPSRC donates £5 million for dementia research

Motivated forgetting often occurs when people feel the most threatened, says study

State highlights: Health care price data and transparency in N.Y. and Calif.; states shift tobacco settlement funds away from prevention

New family of drugs may help combat childhood tumor

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