Immune System News and Research

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Simple blood test could detect early stages of type 1 diabetes

Scientists at the MRC's Clinical Sciences Centre in West London are the first to show that a small molecule circulates in the blood of people who are in the early stages of type 1 diabetes. A simple blood test could detect this biological marker years, maybe decades, before symptoms develop.

9 Jul 2015

Ludwig, CRI launch clinical trials to evaluate immunotherapies for treatment of GBM and solid tumors

Ludwig Cancer Research and the Cancer Research Institute have launched clinical trials evaluating an immunotherapy for the treatment of the brain cancer glioblastoma multiforme (GBM), and a combination of immunotherapies for a variety of solid tumors.

8 Jul 2015

Scientists elucidate which mechanisms block natural killer cells and how this could be lifted

Natural killer cells of the immune system can fend off malignant lymphoma cells and thus are considered a promising therapeutic approach. However, in the direct vicinity of the tumor they lose their effect.

8 Jul 2015

ImmunID announces publication of clinical study data on ImmunTraCkeR assay in the Journal for ImmunoTherapy of Cancer

ImmunID today announced the publication of a short report in the Journal for ImmunoTherapy of Cancer showing that the analysis of peripheral T cell receptor diversity using the company's ImmunTraCkeR assay is associated with clinical outcomes following Ipilimumab treatment in metastatic melanoma.

8 Jul 2015

Immune Pharmaceuticals amends licensing agreement with Endo Pharmaceuticals

Immune Pharmaceuticals, Inc. announced today that it has amended its 2003 Licensing Agreement with Endo Pharmaceuticals Inc., a subsidiary of Endo International plc. As a result, Immune will transfer to Endo its previously licensed patents related to the use of topical lidocaine in acute and chronic back pain and Endo will grant Immune a royalty-free, non-exclusive, fully transferable license to those patents.

8 Jul 2015

SISSA scientists create synthetic enzymes that can differentiate between active and inactive genes

Certain genetic diseases arise from a deficit of specific genes. An enzyme that amplifies gene transcription could be a viable therapy in these cases, as long as genes are not stimulated to work on the wrong part of the body. SISSA scientists have created synthetic "intelligent" enzymes which are able to differentiate between active and inactive genes and selectively stimulate the former ones.

8 Jul 2015

City of Hope offers islet cell transplant program to cure type 1 diabetes

For patients with severe type 1 diabetes, a strict diet and insulin shots are sometimes not enough to sufficiently control their disease. What they need are insulin-producing cells of their own - currently only available through a still-experimental procedure known as islet cell transplantation.

8 Jul 2015

ACCC launches new initiative to facilitate adoption of immuno-oncology in community cancer setting

The Association of Community Cancer Centers today launches the Institute for Clinical Immuno-Oncology, the first of its kind initiative aimed to rapidly facilitate the adoption of immuno-oncology in the community cancer setting.

8 Jul 2015

Cedars-Sinai researchers test new methods for preserving cognition in laboratory mice

Cedars-Sinai researchers have successfully tested two new methods for preserving cognition in laboratory mice that exhibit features of Alzheimer's disease by using white blood cells from bone marrow and a drug for multiple sclerosis to control immune response in the brain.

8 Jul 2015

Researchers develop novel technique to generate activated T cells to tackle advanced melanoma

T cells from patients with melanoma can trigger a protective immune response against the disease according to a new study out of University Hospitals Case Medical Center Seidman Cancer Center and Case Western Reserve University School of Medicine.

8 Jul 2015

UC researcher awarded NCI grant to study effect of MED1 protein on HER2-positive breast cancer

Xiaoting Zhang, PhD, associate professor in the Department of Cancer Biology at the University of Cincinnati College of Medicine, has received a $1.8 million, five-year, R01 award (R01CA197865) from the National Cancer Institute to continue breast cancer research focusing on the function of the protein MED1 on HER2-positive breast cancer.

8 Jul 2015

Study looks at effects of three levels of vitamin D supplementation in overweight, obese blacks

The current recommended minimum daily dose of vitamin D is not sufficient to restore healthy vitamin D levels in overweight or obese blacks, researchers report.

8 Jul 2015

Southern Research receives $22 million to support HIV cure initiative

Southern Research has been awarded a seven-year contract of up to $22 million to support research that could contribute to the cure of HIV disease. Under this contract, Southern Research will develop and standardize assays that quantitate latent reservoirs of HIV.

7 Jul 2015

Study sheds light on how dengue virus adapts, causes outbreaks as it travels

A researcher from The University of Texas Medical Branch at Galveston is an integral member of a collaborative group that is the first to explain the mechanisms that the Dengue virus has developed to optimize its ability to cause outbreaks as it travels across the globe to new places and revisits old ones.

7 Jul 2015

City of Hope researchers to use patients' own modified T cells to treat advanced brain tumors

Already pioneers in the use of immunotherapy, City of Hope researchers are now testing the bold approach to cancer treatment against one of medicine's biggest challenges: brain cancer. This month, they will launch a clinical trial using patients' own modified T cells to fight advanced brain tumors.

7 Jul 2015

Bacterial biofilms play role in development of systemic lupus erythematosus

Lupus, multiple sclerosis, and type-1 diabetes are among more than a score of diseases in which the immune system attacks the body it was designed to defend. But just why the immune system begins its misdirected assault has remained a mystery.

7 Jul 2015

WPI-led study provides clues to new ways to treat difficult-to-cure fungal infections

A study by a multidisciplinary research team, co-directed by Worcester Polytechnic Institute, offers new insights into how virulent fungi adapt through genetic modifications to fight back against the effects of medication designed to block their spread, and how that battle leaves them temporarily weakened. These insights may provide clues to new ways to treat notoriously difficult-to-cure fungal infections like thrush and vaginitis.

7 Jul 2015

Findings reveal new pathway to develop effective treatments and therapies for asthma, allergy

Investigators have discovered the precise molecular steps that enable immune cells implicated in certain forms of asthma and allergy to develop and survive in the body. The findings from Weill Cornell Medical College reveal a new pathway that scientists could use to develop more effective treatments and therapies for the chronic lung disorder.

7 Jul 2015

NIH-sponsored clinical trial evaluates new investigational vaccine against West Nile Virus infection

A clinical trial of a new investigational vaccine designed to protect against West Nile Virus infection will be sponsored by the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health.

7 Jul 2015

Study could provide paradigm shift in treatment of age-related disease, cancer

Intermittent dosing with rapamycin selectively breaks the cascade of inflammatory events that follow cellular senescence, a phenomena in which cells cease to divide in response to DNA damaging agents, including many chemotherapies.

7 Jul 2015

Immune System News and Research

Simple blood test could detect early stages of type 1 diabetes

Ludwig, CRI launch clinical trials to evaluate immunotherapies for treatment of GBM and solid tumors

Scientists elucidate which mechanisms block natural killer cells and how this could be lifted

ImmunID announces publication of clinical study data on ImmunTraCkeR assay in the Journal for ImmunoTherapy of Cancer

Immune Pharmaceuticals amends licensing agreement with Endo Pharmaceuticals

SISSA scientists create synthetic enzymes that can differentiate between active and inactive genes

City of Hope offers islet cell transplant program to cure type 1 diabetes

ACCC launches new initiative to facilitate adoption of immuno-oncology in community cancer setting

Cedars-Sinai researchers test new methods for preserving cognition in laboratory mice

Researchers develop novel technique to generate activated T cells to tackle advanced melanoma

UC researcher awarded NCI grant to study effect of MED1 protein on HER2-positive breast cancer

Study looks at effects of three levels of vitamin D supplementation in overweight, obese blacks

Southern Research receives $22 million to support HIV cure initiative

Study sheds light on how dengue virus adapts, causes outbreaks as it travels

City of Hope researchers to use patients' own modified T cells to treat advanced brain tumors

Bacterial biofilms play role in development of systemic lupus erythematosus

WPI-led study provides clues to new ways to treat difficult-to-cure fungal infections

Findings reveal new pathway to develop effective treatments and therapies for asthma, allergy

NIH-sponsored clinical trial evaluates new investigational vaccine against West Nile Virus infection

Study could provide paradigm shift in treatment of age-related disease, cancer

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