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AI scores breakthrough in anemia treatment with novel PHD inhibitor

Clinical stage generative artificial intelligence (AI)-driven biotechnology company InSilico Medicine ("InSilico"), today announced that the Journal of Medicinal Chemistry, an ACS Publications journal focusing on critical studies about molecular structure and biological activity, has published the company's discovery of a novel PHD inhibitor for the treatment of anemia.

19 Jan 2024

Insilico Medicine leverages AI to identify promising new target for breast and gynecological cancers

Insilico Medicine("Insilico"), a clinical stage generative artificial intelligence (AI)-driven drug discovery company, recently published an early research that it has identified MYT1 as a promising new therapeutic target for breast and gynecological cancer, and discovered a series of novel, potent, and highly selective inhibitors specifically targeting MYT1.

19 Jan 2024

New oral insulin delivered via nano-carriers could soon replace injections

There are approximately 425 million people worldwide with diabetes. Approximately 75 million of these inject themselves with insulin daily.

19 Jan 2024

Unveiling the cellular mechanisms of engram consolidation and memory refinement

Think of a time when you had two different but similar experiences in a short period. Maybe you attended two holiday parties in the same week or gave two presentations at work.

19 Jan 2024

Study analyzes the use of tissue-agnostic therapeutics in patients with primary brain tumors

Researchers from Miami Cancer Institute, part of Baptist Health South Florida, today published a study in Trends in Cancer that analyzes the use of tissue-agnostic therapeutics in patients with primary brain tumors (PBTs).

19 Jan 2024

New discovery sheds light on the genetic basis of a rare skeletal disorder

A McGill-led team of researchers have made an important discovery shedding light on the genetic basis of a rare skeletal disorder.

19 Jan 2024

Mathematical model ushers in era of cost-effective early diabetes detection

A simple blood test could perform better than a complex test thanks to mathematical modeling.

19 Jan 2024

Clinical trial shows MRI and tracking-guided delivery of magnetic stimulation to brains of people with severe depression eases symptoms

Researchers performed a randomized clinical trial to compare resting-state functional magnetic resonance imaging connectivity-guided intermittent theta burst stimulation vs. repetitive transcranial magnetic stimulation for therapy-resistant depression.

19 Jan 2024

Study provides new evidence of weight loss benefits for type 2 diabetes patients

Researchers in the School of Population Health at RCSI University of Medicine and Health Sciences have provided new evidence of the health benefits of weight loss efforts that lead to diabetes remission for type 2 diabetes patients.

18 Jan 2024

New device rapidly provides white blood cell count with a single drop of blood

A Rutgers researcher, through his spinoff company, has led a team to design and test a device that quickly counts a person's white blood cells with a single drop of blood, similar to the way glucometers rapidly scan for blood sugar levels.

18 Jan 2024

Novel imaging approach accurately identifies sub-types of primary aldosteronism

A novel imaging approach, 68Ga-pentixafor PET/CT, has been shown to accurately identify sub-types of primary aldosteronism (an adrenal gland disorder), outperforming traditional methods for diagnosis.

18 Jan 2024

Study explores social and economic factors linked to withdrawal of life support after intracerebral hemorrhage

Living in a high-income neighborhood, having private health insurance, and being older are tied to an increased likelihood that life support will be withdrawn for people who have suffered severe bleeding in the brain, a new study shows.

18 Jan 2024

Remission of diabetes from weight-loss significantly reduces cardiovascular disease risk

While several trials have shown that substantial weight loss using diet and lifestyle can reverse type 2 diabetes, new research published in Diabetologia (the journal of the European Association of the Study of Diabetes [EASD]) is among the first to show the subsequent impact of remission on cardiovascular outcomes.

18 Jan 2024

UNC scientists develop "smart" patch for precision drug delivery

University of North Carolina at Chapel Hill scientists created a new drug delivery system, called the Spatiotemporal On-Demand Patch (SOP), which can receive commands wirelessly from a smartphone or computer to schedule and trigger the release of drugs from individual microneedles.

18 Jan 2024

New structural insights pave the way for drug-resistant malaria therapies

Structural insights into a potent antimalarial drug candidate's interaction with the malaria parasite Plasmodium falciparum have paved the way for drug-resistant malaria therapies, according to a new study by researchers at Weill Cornell Medicine and Van Andel Institute.

18 Jan 2024

Oxford launches LEGACY03 trial to unravel age-related vaccine mysteries

Vaccines are the most effective way to prevent infectious diseases (NHS, 2023) however, people respond to them in different ways.

18 Jan 2024

Machine learning algorithm decodes mutations driving cancer treatment resistance

In a groundbreaking study published on January 18, 2024, in Cancer Discovery, scientists at University of California San Diego School of Medicine leveraged a machine learning algorithm to tackle one of the biggest challenges facing cancer researchers: predicting when cancer will resist chemotherapy.

18 Jan 2024

St. Jude announces $13 million investment to expand the understanding of G-protein coupled receptors

St. Jude Children's Research Hospital today announced a nearly $13 million investment toward a new research collaboration with scientists at Columbia University, Duke University and Stanford University to expand the understanding of G-protein coupled receptors (GPCR), which are vital proteins that impact human health and disease.

18 Jan 2024

ARCHA at Aston University secures £400,000 to recruit four PhD students for dementia research

The Aston Research Centre for Health in Ageing (ARCHA) at Aston University has received £400,000 in funding to recruit four PhD students for a dementia research programme.

18 Jan 2024

Cord blood-derived CAR NK cell therapy targeting CD19 shows promise for treating patients with B-cell malignancies

Researchers from The University of Texas MD Anderson Cancer Center reported promising results in a Phase I/II trial of 37 patients with relapsed or refractory B-cell malignancies who were treated with cord blood-derived chimeric antigen receptor (CAR) natural killer (NK) cell therapy targeting CD19.

18 Jan 2024

Medicine News and Research

AI scores breakthrough in anemia treatment with novel PHD inhibitor

Insilico Medicine leverages AI to identify promising new target for breast and gynecological cancers

New oral insulin delivered via nano-carriers could soon replace injections

Unveiling the cellular mechanisms of engram consolidation and memory refinement

Study analyzes the use of tissue-agnostic therapeutics in patients with primary brain tumors

New discovery sheds light on the genetic basis of a rare skeletal disorder

Mathematical model ushers in era of cost-effective early diabetes detection

Clinical trial shows MRI and tracking-guided delivery of magnetic stimulation to brains of people with severe depression eases symptoms

Study provides new evidence of weight loss benefits for type 2 diabetes patients

New device rapidly provides white blood cell count with a single drop of blood

Novel imaging approach accurately identifies sub-types of primary aldosteronism

Study explores social and economic factors linked to withdrawal of life support after intracerebral hemorrhage

Remission of diabetes from weight-loss significantly reduces cardiovascular disease risk

UNC scientists develop "smart" patch for precision drug delivery

New structural insights pave the way for drug-resistant malaria therapies

Oxford launches LEGACY03 trial to unravel age-related vaccine mysteries

Machine learning algorithm decodes mutations driving cancer treatment resistance

St. Jude announces $13 million investment to expand the understanding of G-protein coupled receptors

ARCHA at Aston University secures £400,000 to recruit four PhD students for dementia research

Cord blood-derived CAR NK cell therapy targeting CD19 shows promise for treating patients with B-cell malignancies

Everything there is to know about biosimilars eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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