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Study provides new understanding of the earliest molecular events in Type 1 Diabetes pathogenesis

For the first time, researchers have revealed that during the development of Type 1 Diabetes (T1D), when insulin-producing cells in the pancreas are under attack from T lymphocytes, the cells lining the pancreatic duct reprogram themselves in an attempt to suppress autoimmune T cell responses.

28 Feb 2022

A study on the evolution of avian coronavirus escape mutants in vitro

A recent study included an in vitro assessment of the effect of antibody titers and vaccine combinations on the emergence of escape mutants of AvCoV.

28 Feb 2022

Study compares heterologous and homologous third vaccination in kidney transplant recipients

A new study assesses the comparative neutralizing antibody level elicited by three mRNA vaccine doses to a heterologous COVID-19 vaccine regimen.

28 Feb 2022

Researchers show a relationship between regionalized myocardial fibrosis and mitral valve prolapse

The larger the sail, the more wind it catches. But as that size increases, so does the stress experienced by each sheet and line connected to the canvas.

28 Feb 2022

Novel molecular pathway shared by two neurodegenerative disorders discovered

Scientists from two independent research teams have discovered how the mislocalization of a protein, known as TDP-43, alters the genetic instructions for UNC13A, providing a possible therapeutic target that could also have implications in treating amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and other forms of dementia.

28 Feb 2022

NYITCOM researchers secure NIH grant to investigate diabetic heart failure treatments

A research team from New York Institute of Technology College of Osteopathic Medicine, led by Biomedical Sciences Instructor Satoru Kobayashi, Ph.D., has secured a grant from the National Institutes of Health National Heart, Lung, and Blood Institute.

28 Feb 2022

MUSC study sheds light on better ways to prevent and treat colorectal cancer

An MUSC Hollings Cancer Center study sheds light on better ways to prevent and treat colorectal cancer, which often is found at advanced stages when it's much harder to treat.

28 Feb 2022

New data analysis tool reveals immune cell types associated with COVID-19 mortality risk

A new data analysis tool developed by Yale researchers has revealed the specific immune cell types associated with increased risk of death from COVID-19, they report Feb. 28 in the journal Nature Biotechnology.

28 Feb 2022

Novel mechanism that connects circadian rhythm and muscle repair discovered

Northwestern Medicine investigators have discovered a novel mechanism that connects circadian rhythm-controlled cellular metabolism and regeneration with muscle repair after injury, according to recent findings published in the journal Genes and Development.

28 Feb 2022

Study reveals new way viruses trigger autoimmunity

Autoimmune diseases such as rheumatoid arthritis and Type 1 diabetes are thought to arise when people with a genetic susceptibility to autoimmunity encounter something in the environment that triggers their immune systems to attack their own bodies.

28 Feb 2022

New imaging approach provides a clearer ‘picture’ of blood vessels in health and disease

Johns Hopkins Medicine researchers have developed and tested a new imaging approach they say will accelerate imaging-based research in the lab by allowing investigators to capture images of blood vessels at different spatial scales.

28 Feb 2022

Researchers develop new precision medicine technology for cancer immunotherapy

In recent years, great advances have been made in the development of new successful immunotherapies to treat cancer. CAR T-cell therapy and antibody treatments are two types of targeted immunotherapies that have revolutionized areas of cancer care.

28 Feb 2022

Histopathologic and molecular effects in the placenta after SARS-CoV-2 infection during pregnancy

A recent study evaluated the molecular and histopathological effects in the placenta following a SARS-CoV-2 infection during pregnancy.

28 Feb 2022

Immunity before and after the SARS-CoV-2 Omicron variant in South Africa

Researchers conducted a national epidemiological survey to determine the seropositivity against SARS-CoV-2 before the emergence of the novel Omicron variant of concern.

28 Feb 2022

Peptide-based vaccine fails to protect mice against SARS-CoV-2 despite T cell response

A recent study observed that peptide-based vaccination against SARS-CoV-2 failed to protect mice against COVID-19, albeit eliciting T cell responses.

28 Feb 2022

ESMO announces a new series of resources to guide physicians in oncological practice

ESMO, the leading professional organization for medical oncology, announces a new series of resources designed to guide physicians in areas of oncological practice not covered by guidelines, where current evidence is insufficient to evenly inform clinical decision-making.

28 Feb 2022

B Cell News and Research

Study provides new understanding of the earliest molecular events in Type 1 Diabetes pathogenesis

A study on the evolution of avian coronavirus escape mutants in vitro

Study compares heterologous and homologous third vaccination in kidney transplant recipients

Researchers show a relationship between regionalized myocardial fibrosis and mitral valve prolapse

Novel molecular pathway shared by two neurodegenerative disorders discovered

NYITCOM researchers secure NIH grant to investigate diabetic heart failure treatments

MUSC study sheds light on better ways to prevent and treat colorectal cancer

New data analysis tool reveals immune cell types associated with COVID-19 mortality risk

Novel mechanism that connects circadian rhythm and muscle repair discovered

Study reveals new way viruses trigger autoimmunity

New imaging approach provides a clearer ‘picture’ of blood vessels in health and disease

Researchers develop new precision medicine technology for cancer immunotherapy

Histopathologic and molecular effects in the placenta after SARS-CoV-2 infection during pregnancy

Immunity before and after the SARS-CoV-2 Omicron variant in South Africa

Peptide-based vaccine fails to protect mice against SARS-CoV-2 despite T cell response

ESMO announces a new series of resources to guide physicians in oncological practice

Health events amongst pregnant females after COVID-19 vaccination

Triple antibody cocktail is a promising candidate for immunotherapy against SARS-CoV-2 variants of concern

The need for a holistic and unbiased approach to develop a more universal vaccine for coronaviruses

Study finds Omicron sublineage BA.2 is less pathogenic in rodent models than prior SARS-CoV-2 variants

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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