Protein C News and Research

RSS

Gift boosts efforts to understand and combat rare cancers

Curing cancer has been the dream of countless doctors and researchers over the decades. Yet some types of cancer, whether because they affect relatively few people or lack influential advocates, receive less attention and funding than others.

9 Apr 2021

Novel protein transport system mediates toxin secretion by tuberculosis pathogen

Six years ago, Michael Niederweis, Ph.D., described the first toxin ever found for the deadly pathogen Mycobacterium tuberculosis.

9 Apr 2021

Study reveals molecular mechanisms of drug resistance in Mycobacterium tuberculosis

A consortium of researchers from Russia, Belarus, Japan, Germany and France led by a Skoltech scientist have uncovered the way in which Mycobacterium tuberculosis survives in iron-deficient conditions by utilizing rubredoxin B, a protein from a rubredoxin family that play an important role in adaptation to changing environmental conditions.

9 Apr 2021

Novel PF74 molecule effectively targets HIV capsid protein

Of all known small molecules targeting human immunodeficiency virus (HIV) capsid protein (CA), PF74 represents by far the best characterized chemotype, due to its ability to confer antiviral phenotypes in both early and late phases of viral replication.

9 Apr 2021

Study shows how melanoma cells evade detection and destruction by immune cells

A dysfunctional immune system significantly contributes to the development of cancer. Several therapeutic strategies to activate the immune system to target cancer cells have been approved to treat different types of cancer, including melanoma.

9 Apr 2021

Altered calcium signaling is linked to early-stage Alzheimer's pathology

Alzheimer's disease is known for its slow attack on neurons crucial to memory and cognition. But why are these particular neurons in aging brains so susceptible to the disease's ravages, while others remain resilient?

9 Apr 2021

Oxford-AstraZeneca COVID vaccine induces cell spikes similar to SARS-CoV-2's

Scientists from the University of Oxford and the University of Southampton report in the journal ACS Central Science that cells infected with the ChAdOx1 vaccine produce spike proteins on the cells similar to those produced by natural SARS-CoV-2 infection.

9 Apr 2021

More new SARS-CoV-2 variants are highly likely

In a recent report posted to the bioRxiv preprint server, researchers from the United Kingdom and Uganda reveal unique protein features of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) relative to other representatives of Sarbecoviruses.

8 Apr 2021

Powerful algorithms can 'predict' the biological language of cancer and Alzheimer's

Powerful algorithms used by Netflix, Amazon and Facebook can 'predict' the biological language of cancer and neurodegenerative diseases like Alzheimer's, scientists have found.

8 Apr 2021

Researchers identify nonelectrical cells that transition the brain from plasticity to stability

Researchers exploring the developing central nervous system of fruit flies have identified nonelectrical cells that transition the brain from highly plastic into a less moldable, mature state.

8 Apr 2021

Mutations to autism-associated gene cause a cascade of problems in developing mouse brains

Damage to the autism-associated gene Dyrk1a, sets off a cascade of problems in developing mouse brains, resulting in abnormal growth-factor signaling, undergrowth of neurons, smaller-than-average brain size, and, eventually, autism-like behaviors, a new study from Scripps Research, Florida, finds.

8 Apr 2021

Novel mRNA delivery system produces a therapeutic protein that protects neurons from ischemia

A lack of oxygen to brain tissue--known as ischemia--leads to the death of neurons, which results in stroke. Despite considerable research, there are currently no treatments that successfully prevent neuronal death.

8 Apr 2021

Moderna COVID-19 vaccine ensures long-term protection against SARS-CoV-2 infection, suggests study

A recent report published in the New England Journal of Medicine has revealed that the COVID-19 vaccine developed by Moderna, Inc, USA, is capable of inducing robust and durable antibody responses for at least six months post-vaccination.

8 Apr 2021

Breath Analysis: How Could it Improve Healthcare and Diagnosis?

In this interview, News-Medical talks to Santi Dominguez (SD) and Michael Graz (MG), CEOs at Imspex Diagnostics and Imspex Medical respectively, about the role breath analysis has to play in healthcare and diagnosis.

From Imspex Medical 8 Apr 2021

Prefusion SARS-CoV-2 spike-based vaccine candidate shows high safety and efficacy in phase I trial

A new preprint research paper posted to the medRxiv server reports the results of the first human trial of the prefusion stabilized SARS-CoV-2 spike vaccine MVC-COV1901 in Taiwan.

8 Apr 2021

Mouse monoclonal antibodies protect against SARS-CoV-2 wildtype, UK and South African variants

A new preprint research paper posted to the bioRxiv server reports on the ability of a set of neutralizing mouse antibodies to protect mice against multiple lineages of SARS-CoV-2.

8 Apr 2021

Microrna-29 molecule controls brain maturation in mammals

A team led by scientists at the UNC School of Medicine identified a molecule called microRNA-29 as a powerful controller of brain maturation in mammals. Deleting microRNA-29 in mice caused problems very similar to those seen in autism, epilepsy, and other neurodevelopmental conditions.

8 Apr 2021

Landmark discovery may lead to safe, effective antiviral drugs against COVID-19

The COVID-19 vaccines currently rolling out are providing hope that the spread of the disease can be halted. But infection rates are still high, and for those who contract COVID-19, the search for effective treatments remains important.

8 Apr 2021

Hydrogels offer new hope for cancer treatment

Hydrogels are often used as drug delivery systems, but to be effective carriers for anti-cancer drugs, they need to be responsive to varied stimuli in the tumor microenvironment.

8 Apr 2021

Leaky gut and microbial dysbiosis could contribute to cytokine storm in severely ill COVID-19 cases

The gut is a well-established route of infection and target for viral damage by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent for COVID-19. This is supported by the clinical observation that about half of COVID-19 patients exhibit gastrointestinal (GI) symptoms.

8 Apr 2021

Protein C News and Research

Gift boosts efforts to understand and combat rare cancers

Novel protein transport system mediates toxin secretion by tuberculosis pathogen

Study reveals molecular mechanisms of drug resistance in Mycobacterium tuberculosis

Novel PF74 molecule effectively targets HIV capsid protein

Study shows how melanoma cells evade detection and destruction by immune cells

Altered calcium signaling is linked to early-stage Alzheimer's pathology

Oxford-AstraZeneca COVID vaccine induces cell spikes similar to SARS-CoV-2's

More new SARS-CoV-2 variants are highly likely

Powerful algorithms can 'predict' the biological language of cancer and Alzheimer's

Researchers identify nonelectrical cells that transition the brain from plasticity to stability

Mutations to autism-associated gene cause a cascade of problems in developing mouse brains

Novel mRNA delivery system produces a therapeutic protein that protects neurons from ischemia

Moderna COVID-19 vaccine ensures long-term protection against SARS-CoV-2 infection, suggests study

Breath Analysis: How Could it Improve Healthcare and Diagnosis?

Prefusion SARS-CoV-2 spike-based vaccine candidate shows high safety and efficacy in phase I trial

Mouse monoclonal antibodies protect against SARS-CoV-2 wildtype, UK and South African variants

Microrna-29 molecule controls brain maturation in mammals

Landmark discovery may lead to safe, effective antiviral drugs against COVID-19

Hydrogels offer new hope for cancer treatment

Leaky gut and microbial dysbiosis could contribute to cytokine storm in severely ill COVID-19 cases

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Latest News