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SARS-CoV-2 viroporins mediate cytokine storm via mitochondrial permeability transition pore

Researchers demonstrated that the SARS-CoV-2 viroporins precipitate cytokine storm via the alteration of mitochondrial physiology in severe COVID-19.

24 Feb 2022

Study reveals sex-dimorphic immune imprints and in vivo functional impacts of mild COVID-19

Researchers used a systems immunology approach to analyze the immune states of healthy and non-obese subjects who recovered from mild COVID-19 and compared them with age- and sex-matched COVID-19-naive controls.

24 Feb 2022

Immunological landscape of England during Omicron-driven SARS-CoV-2 wave

In a new study, researchers determined the immunological landscape of England throughout the SARS-CoV-2 Omicron wave.

24 Feb 2022

Research reveals why a common genetic variant worsens outcomes for people with ALS and FTD

A pioneering new study led by UCL and National Institutes of Health (NIH) scientists has revealed, for the first time, why a common genetic variant worsens disease outcomes for people with the devastating adult-onset neurodegenerative diseases amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).

24 Feb 2022

Immune responses in patients with varying degrees of SARS-CoV-2 infection

In a recent research article published in the journal PLoS ONE, researchers looked at immunological responses in relation to established risk factors for serious illness. This prospective cohort study reports on long-lasting SARS-CoV-2 specific antibody and T-cellular immune responses six months after infection in rt-PCR confirmed cases of different illness severity (community and hospitalized patients).

24 Feb 2022

Scientists discover how a rare genetic disorder disrupts key neural interactions in the developing brain

Every time you chew, talk, yawn, or sense the zap of a toothache, cranial nerve cells are shuttling electrochemical signals to your brain.

23 Feb 2022

Study shows how certain RNA molecules control the repair of damaged DNA in cancer cells

A new study from Karolinska Institutet in Sweden shows how certain RNA molecules control the repair of damaged DNA in cancer cells, a discovery that could eventually give rise to better cancer treatments. The study is published today in the journal Nature Communications.

23 Feb 2022

Study on Omicron related mortality in cancer patients during recent COVID wave

A recent pre-proof study published in the journal Cancer Cell assessed the CFR of cancer patients during the third wave of the coronavirus disease 2019 (COVID-19) pandemic caused by the SARS-CoV-2 Omicron variant.

23 Feb 2022

Tiny lipid-based nanoparticles carry genetic instructions directly into the lungs

Researchers at the Tufts University School of Engineering are building a reputation for precision targeting in drug delivery.

23 Feb 2022

Discovery of signaling pathway in immune cells may lead to new therapeutic approach for autoimmune diseases

Autoimmune diseases are triggered when the immune system malfunctions and attacks the body's own structures.

23 Feb 2022

Neanderthal gene makes people susceptible to COVID-19, but protects against HIV

A study recently published in the top-tier journal Proceedings of the National Academy of Sciences of the United States of America (PNAS) shows how a specific gene flow from Neandertals can act as a double-edged sword by increasing the risk for the development of severe coronavirus disease 2019 (COVID-19), and at the same time decreasing the risk for the infection with the human immunodeficiency virus (HIV).

23 Feb 2022

Cell stress-related biochemical events may be partly driving Parkinson's disease

Parkinson's disease may be driven in part by cell stress-related biochemical events that disrupt a key cellular cleanup system, leading to the spread of harmful protein aggregates in the brain, according to a new study from scientists at Scripps Research.

23 Feb 2022

Merkel cell carcinoma has a higher post-treatment recurrence rate than other skin cancers

Patients treated for Merkel cell carcinoma (MCC) face a five-year recurrence rate of 40% - markedly higher than the recurrence rates for melanoma and other skin cancers, according to research published today in JAMA Dermatology.

23 Feb 2022

Genetics may influence how the body responds to vaccines and boosters

Genetics play an important role in how our bodies respond to vaccines and booster shots, suggesting that certain protective responses elicited by vaccination could be more effective with personalization, according to a new study led by University of Michigan researchers.

23 Feb 2022

New combination treatment strategy for managing metastatic hormone-sensitive prostate cancer

A new drug, administered in combination with standard androgen-deprivation therapy and docetaxel chemotherapy, increased survival in patients with metastatic hormone-sensitive prostate cancer, according to a trial published in The New England Journal of Medicine.

23 Feb 2022

B Cell News and Research

SARS-CoV-2 viroporins mediate cytokine storm via mitochondrial permeability transition pore

Study reveals sex-dimorphic immune imprints and in vivo functional impacts of mild COVID-19

Immunological landscape of England during Omicron-driven SARS-CoV-2 wave

Research reveals why a common genetic variant worsens outcomes for people with ALS and FTD

Immune responses in patients with varying degrees of SARS-CoV-2 infection

Scientists discover how a rare genetic disorder disrupts key neural interactions in the developing brain

Study shows how certain RNA molecules control the repair of damaged DNA in cancer cells

Study on Omicron related mortality in cancer patients during recent COVID wave

Tiny lipid-based nanoparticles carry genetic instructions directly into the lungs

Discovery of signaling pathway in immune cells may lead to new therapeutic approach for autoimmune diseases

Neanderthal gene makes people susceptible to COVID-19, but protects against HIV

Cell stress-related biochemical events may be partly driving Parkinson's disease

Merkel cell carcinoma has a higher post-treatment recurrence rate than other skin cancers

Genetics may influence how the body responds to vaccines and boosters

New combination treatment strategy for managing metastatic hormone-sensitive prostate cancer

Researchers show how the biological system can be steered with artificial organic neurons

Researchers create artificial tendons in vitro from human stem cells

Real-time imaging shows cells of developing fruit fly eye move into position

Tissue engineering advance could one day help patients regrow bones

White blood cell count as a prognostic indicator of COVID-19

Immunology eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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