Genetic News and Research

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Fewer kids enroll in pediatric oncology clinical trials, study shows

Historically, pediatric cancer patients have been much more likely than adult cancer patients to enroll in clinical trials as part of their treatment.

23 Apr 2020

Low-cost, portable detector takes about 30 minutes to identify pathogens

Most viral test kits rely on labor- and time-intensive laboratory preparation and analysis techniques; for example, tests for the novel coronavirus can take days to detect the virus from nasal swabs.

23 Apr 2020

Researchers discover physiological mechanisms underlying pediatric B-ALL

B-cell acute lymphoblastic leukemia (B-ALL) is characterized by the accumulation of abnormal immature B-cell precursors in the bone marrow and is the most common pediatric cancer.

23 Apr 2020

People with metabolic syndrome can benefit from light physical exercise

Physical exercise can act prophylactically for people with the metabolic syndrome and protect them against cardiovascular diseases, a new study from the Swedish School of Sport and Health Sciences, GIH, and Karolinska Institutet, Sweden, published in the European Journal of Preventive Cardiology reports.

23 Apr 2020

Breakthrough discovery in HIV research opens path to new, better therapies

New research on the human immunodeficiency virus (HIV) structure has revealed a promising novel drug target for treating it.

23 Apr 2020

Combinations of PAC and WFA are highly synergistic against proliferation of non-small cell lung cancer

Oncotarget Volume 11 Issue 16 showed that the sensitivity of H1299 and A549 cells to concomitant treatment with PAC and WFA was greater than that of either PAC or WFA alone.

23 Apr 2020

New study on African bats charts new ways to share and link published data

Newly published findings about the phylogenetics and systematics of some previously known, but also other yet to be identified species of Old World Leaf-nosed bats, provide the first contribution to a recently launched collection of research articles, whose task is to help scientists from across disciplines to better understand potential hosts and vectors of zoonotic diseases, such as the Coronavirus.

23 Apr 2020

Many cells in human uterus carry 'cancer-driving' mutations that arise early in life

Many cells in the inner lining of the uterus carry 'cancer-driving' mutations that frequently arise early in life, report scientists from the Wellcome Sanger Institute, the University of Cambridge and their collaborators.

23 Apr 2020

UMD professor outlines new theoretical framework for heredity

The common view of heredity is that all information passed down from one generation to the next is stored in an organism's DNA. But Antony Jose, associate professor of cell biology and molecular genetics at the University of Maryland, disagrees.

23 Apr 2020

Georgia Tech researchers create key components for COVID-19 tests

Gaps in the supply of coronavirus tests are propelling initiatives to fill them across the country. At the Georgia Institute of Technology, bioscience researchers are burning midnight oil to produce key components for tests in the state of Georgia.

23 Apr 2020

Indiana Network for Population Health aims to address the social determinants of health

The Indiana Network for Population Health has been launched by the Regenstrief Institute and collaborators, including the State of Indiana, Indiana University and the Indiana Health Information Exchange, to provide the secure exchange of comprehensive data -- especially information on social determinants of health such as housing stability and access to nutritious food -- to researchers, policy makers, healthcare providers and others on the front lines fighting opioid and other addictions.

23 Apr 2020

Study: Patients’ genetically edited stem cells successfully reversed diabetes in mice

Using induced pluripotent stem cells produced from the skin of a patient with a rare, genetic form of insulin-dependent diabetes called Wolfram syndrome, researchers transformed the human stem cells into insulin-producing cells and used the gene-editing tool CRISPR-Cas9 to correct a genetic defect that had caused the syndrome.

22 Apr 2020

Genomic sequencing shows COVID-19 spread patterns

Throughout the spread of the virus, genomic sequencing has played a role in epidemiologic tracking of the viral strains carried all over the world. Such strains are traced back to their origin by their unique mutations and help to link remote infections.

22 Apr 2020

Coronavirus has mutated into at least 30 variants

The coronavirus disease (COVID-19) continues to threaten millions of people across the globe, and lockdowns appear set to remain in place in many countries amid rising death tolls, as governments decide whether to extend restrictions aimed at reducing the spread of the virus. Now, a new study reveals that the novel coronavirus has mutated into at least 30 different genetic variants, affecting different parts of the world.

22 Apr 2020