Immune System News and Research

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Vitamin K-deficient bleeding increasingly common in newborns

Vitamin K, which has been administered to newborns as an injection since it was first recommended by the American Academy of Pediatrics in 1961, is vital for blood to clot normally. Despite it being given as standard medical practice since then, vitamin K-deficient bleeding (VKDB) is being seen more often in newborns than it has in decades.

23 Jun 2015

PROMISSE study: Most women with lupus can expect good pregnancy outcomes

One of the most important and anxiety-producing concerns among patients with lupus is whether it is safe to become pregnant. A pioneering study led by researchers at Hospital for Special Surgery has shown that most women can expect a good pregnancy outcome if their lupus is inactive and they are free of certain risk factors.

23 Jun 2015

High-fat, high-sugar diet can cause bacterial changes that appear related to loss of 'cognitive flexibility'

A study at Oregon State University indicates that both a high-fat and a high-sugar diet, compared to a normal diet, cause changes in gut bacteria that appear related to a significant loss of "cognitive flexibility," or the power to adapt and adjust to changing situations.

23 Jun 2015

Stress during pregnancy affects babies' brain development

Stress during the first trimester of pregnancy alters the population of microbes living in a mother's vagina. Those changes are passed on to newborns during birth and are associated with differences in their gut microbiome as well as their brain development, according to a new study by University of Pennsylvania researchers.

23 Jun 2015

Vaxil's ImMucin receives FDA orphan drug designation for treatment of multiple myeloma

Vaxil Bio, a company specializing in the development of immunotherapy-based drugs, reports today that its lead product, ImMucin, has been granted an "orphan drug" designation by the US Food and Drug Administration, for the treatment of multiple myeloma (MM).

22 Jun 2015

Experimental vaccine candidate can stimulate immune system activity to prevent HIV infection

New research led by scientists at The Scripps Research Institute (TSRI), International AIDS Vaccine Initiative (IAVI) and The Rockefeller University shows in mice that an experimental vaccine candidate designed at TSRI can stimulate the immune system activity necessary to stop HIV infection. The findings could provide key information for the development of an effective AIDS vaccine.

22 Jun 2015

Researchers use different approaches to test ways to manipulate nanoparticles in medicine

Nanoparticles are the smallest particles capable of reaching virtually all parts of the body. Researchers use various approaches to test ways in which nanoparticles could be used in medicine - for instance, to deliver substances to a specific site in the body such as a tumor.

22 Jun 2015

Small intestine causes chronic inflammation in obese patients

Obesity is caused by numerous and complex factors, some of which are as yet unsuspected. Scientists from the CNRS, INSERM, UPMC and Université Paris Descartes, working with research clinicians from Paris Public Hospitals (AP-HP) have now shown that severe obesity is accompanied by inflammation of the small intestine and enhanced immune response in that region.

22 Jun 2015

Planning for first clinical trial of MERS-CoV vaccine candidate now underway

Researchers from Ludwig-Maximilians-Universitaet in Munich have demonstrated, in a preclinical setting, the protective effect of a candidate vaccine directed against the coronavirus that causes Middle East Respiratory Syndrome. Planning for the first clinical trial is now underway.

22 Jun 2015

Celimmune to provide oral presentation on AMG 714 antibody at 16th International Coeliac Disease Symposium

Celimmune LLC, a clinical development-stage immunotherapy company focused on treating and preventing autoimmune diseases, announced today that Dr. Francisco Leon, CEO and Chief Medical Officer, will provide an oral presentation on an abstract related to the company's lead product candidate, AMG 714, at the 16th International Coeliac Disease Symposium, June 24, 2015, in Prague, Czech Republic.

22 Jun 2015

Cardiac device wearers ought to keep safe distance from smartphones to prevent unwanted painful shocks

Cardiac device wearers should keep a safe distance from smartphones to avoid unwanted painful shocks or pauses in function, reveals research presented today at EHRA EUROPACE -- CARDIOSTIM 2015 by Dr. Carsten Lennerz, first author and cardiology resident in the Clinic for Heart and Circulatory Diseases, German Heart Centre, Munich, Germany.

22 Jun 2015

Study explores effects of household smoking on children's later weight gain

Children whose parents smoked when they were toddlers are likely to have a wider waist and a higher BMI by time they reach ten years of age, reveal researchers at the University of Montreal and its affiliated CHU Sainte Justine Research Centre. "We suspect the statistics we've established linking childhood obesity to exposure to parents' smoking may underestimate the effect due to parents under reporting the amount they smoked out of shame," explained Professor Linda Pagani, who led the study.

22 Jun 2015

Drug discovery experts receive £3m to find new treatments for Alzheimer's disease

Funding worth nearly half a million pounds will unite academics at the University of Southampton with drug discovery experts at the medical research charity MRC Technology, to target the immune system in the hunt for new treatments for Alzheimer's disease.

19 Jun 2015

UNC Lineberger scientists contribute to better understanding of genetic mutations in melanoma

UNC Lineberger Comprehensive Cancer Center researchers have significantly contributed to a better understanding of the genetic alterations found in cutaneous melanoma, the most lethal form of skin cancer, as part of a multi-institution, international effort of The Cancer Genome Atlas.

19 Jun 2015

Scientists identify four melanoma subtypes that share common 'downstream' signaling pathways

Cutaneous melanoma, the most deadly form of skin cancer, is now believed to be divided into four distinct genomic subtypes, say researchers at The University of Texas MD Anderson Cancer Center, a finding that could prove valuable in the ever-increasing pursuit of personalized medicine.

19 Jun 2015

Preventing neutrophils from producing NETs can accelerate wound healing in diabetic mice

One of the body's tools for fighting off infection in a wound may actually slow down the healing process, according to new research by a team of Harvard University, Boston Children's Hospital, and Penn State University scientists.

19 Jun 2015

New book examines all aspects of HBV and HDV infections

Despite the availability of an effective vaccine for hepatitis B, hundreds of millions of people worldwide are infected with the hepatitis B virus (HBV). This virus can cause serious liver damage and cancer in chronically infected patients. Hepatitis delta virus (HDV), a satellite of HBV, can exacerbate the disease.

19 Jun 2015

Mayo Clinic, TGen researchers help launch national clinical trial to treat advanced skin cancer patients

Mayo Clinic and the Translational Genomics Research Institute are helping launch a national clinical trial that will apply the latest in precision medicine to treat advanced melanoma skin cancer.

19 Jun 2015

Three studies describe advances toward development of antibodies to stop HIV

A trio of studies being published today in the journals Science and Cell describes advances toward the development of an HIV vaccine. The three study teams all demonstrated techniques for stimulating animal cells to produce antibodies that either could stop HIV from infecting human cells in the laboratory or had the potential to evolve into such antibodies.

19 Jun 2015

Sequence of immunizations could be the promising route to HIV vaccine

The secret to preventing HIV infection lies within the human immune system, but the more-than-25-year search has so far failed to yield a vaccine capable of training the body to neutralize the ever-changing virus. New research from The Rockefeller University, and collaborating institutions, suggests no single shot will ever do the trick. Instead, the scientists find, a sequence of immunizations might be the most promising route to an HIV vaccine.

19 Jun 2015

Immune System News and Research

Vitamin K-deficient bleeding increasingly common in newborns

PROMISSE study: Most women with lupus can expect good pregnancy outcomes

High-fat, high-sugar diet can cause bacterial changes that appear related to loss of 'cognitive flexibility'

Stress during pregnancy affects babies' brain development

Vaxil's ImMucin receives FDA orphan drug designation for treatment of multiple myeloma

Experimental vaccine candidate can stimulate immune system activity to prevent HIV infection

Researchers use different approaches to test ways to manipulate nanoparticles in medicine

Small intestine causes chronic inflammation in obese patients

Planning for first clinical trial of MERS-CoV vaccine candidate now underway

Celimmune to provide oral presentation on AMG 714 antibody at 16th International Coeliac Disease Symposium

Cardiac device wearers ought to keep safe distance from smartphones to prevent unwanted painful shocks

Study explores effects of household smoking on children's later weight gain

Drug discovery experts receive £3m to find new treatments for Alzheimer's disease

UNC Lineberger scientists contribute to better understanding of genetic mutations in melanoma

Scientists identify four melanoma subtypes that share common 'downstream' signaling pathways

Preventing neutrophils from producing NETs can accelerate wound healing in diabetic mice

New book examines all aspects of HBV and HDV infections

Mayo Clinic, TGen researchers help launch national clinical trial to treat advanced skin cancer patients

Three studies describe advances toward development of antibodies to stop HIV

Sequence of immunizations could be the promising route to HIV vaccine

Understanding the DNA Damage Response in Innate Immunity eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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