DNA Sequencing News and Research

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Scientists develop novel approach to detect long-distance chromosomal interactions for CAD

The discovery that a "gene desert" on chromosome 9 was a hotspot for coronary artery disease (CAD) risk was among the highlights of findings produced recently by genome-wide association studies, which compare the genomes of many people for genetic variations and have been broadly used in the past few years to study hundreds of diseases and complex traits. Gene deserts are large genomic segments devoid of genes.

10 Feb 2011

Partek signs distribution agreement with Life Technologies

Partek Incorporated, a global leader in bioinformatics software, announced today the signing of a distribution agreement with Life Technologies Corporation, a provider of next-generation DNA sequencing technology. The agreement makes Partek Genomics Suite available through Life Technologies as a featured solution for analyzing data generated by Life Technologies' next-generation sequencing devices.

5 Feb 2011

Data generated on Ion Torrent PGM sequencer to be presented at AGBT

Life Technologies Corporation, today announced that just six weeks following the launch of the Ion Torrent PGM sequencer, independent researchers will present data they generated with the system at the annual Advances in Genome Biology and Technology (AGBT) conference.

4 Feb 2011

NIH awards CCTSI $2.2 million grant to advance personalized medicine

A federal grant totaling $2.2 million shows how the University of Colorado School of Medicine and Anschutz Medical Campus are using technology to advance the cutting-edge field of personalized medicine -- tailoring treatments to the individual based on their genetic make-up.

28 Jan 2011

Scientist identifies polymorphism that raises risk of poor outcomes in preterm infants

Researchers at Cincinnati Children's Hospital Medical Center have identified biomarkers of poor outcomes in preterm infants that may help identify new approaches to prevention.

28 Jan 2011

Golden Helix releases new Sequence Analysis Module for SNP & Variation Suite

Golden Helix, Inc. today announced the release of a new Sequence Analysis Module for its SNP & Variation Suite software. The new module introduces innovative tertiary analysis methods for next-generation DNA sequencing studies.

27 Jan 2011

Common genetic risk factor for heart failure in Caucasians also linked to kidney function

Nearly five million Americans live with heart failure, with as many as 700,000 new cases diagnosed each year. In addition to lifestyle factors, scientists have shown that heart failure has a strong heritable component, but identifying the responsible genes has been a major challenge. Now, new research has identified a common genetic risk factor for heart failure in Caucasians that is also linked to kidney function.

19 Jan 2011

Researchers find kidney-specific gene defects may increase risk of heart failure

Scientists have identified the first DNA sequence variant common in the population that is not only associated with an increased risk of heart failure, but appears to play a role in causing it.

18 Jan 2011

DNAVision purchases 4 of Life Technologies' NGS platforms

DNAVision, one of European leading genetic analysis service providers, is pleased to announce the purchase of four next-generation sequencing platforms from Life Technologies, including two latest 5500xl SOLiD™ Systems.

13 Jan 2011

Life Technologies announces new DNA sequencing portfolio for lab research

Life Technologies Corporation today announced a series of new product innovations across the company's DNA sequencing portfolio. To date, most sequencing technologies have primarily addressed the needs of researchers in the highest throughput laboratories, limiting widespread accessibility of these powerful next-generation sequencing technologies.

12 Jan 2011

Single cellular crisis shatters chromosomes in cancer causation

Remarkable new research overthrows the conventional view that cancer always develops in a steady, stepwise progression. It shows that in some cancers, the genome can be shattered into hundreds of fragments in a single cellular catastrophe, wreaking mutation on a massive scale.

7 Jan 2011

Spirogen, Genentech enter multi-year ADC research collaboration and license agreement

Spirogen Ltd. a leading oncology-focused company developing DNA sequence targeted agents, announced a multi-year research collaboration and license agreement with Genentech, a member of the Roche Group.

7 Jan 2011

First whole genome sequence of Parsi breast cancer woman

Avesthagen Limited has yet again established its position as a leader in the successful application of next gen technologies as it announces the completion of the first Parsi breast cancer whole genome sequence of a 74-year-old Parsi woman with a heritable form of breast cancer. The incidence of breast cancer in most populations is strongly linked to a genetic basis but little is known about the variants at the present time.

4 Jan 2011

Hydrocephalus in Ugandan children linked to farm animals, previous bacterial infection

Hydrocephalus in Ugandan children and other developing countries is seasonal, linked to farm animals and in part, caused by previous bacterial infection, according to an international team of researchers from Uganda and the United States, who believe that the best approach to this problem is prevention.

3 Jan 2011

Paternal diet affects lipid metabolizing genes in offspring

Scientists at the University of Massachusetts Medical School and the University of Texas at Austin have uncovered evidence that environmental influences experienced by a father can be passed down to the next generation, "reprogramming" how genes function in offspring. A new study published this week in Cell shows that environmental cues-in this case, diet-influence genes in mammals from one generation to the next, evidence that until now has been sparse.

24 Dec 2010

BioTime enters MTA with UC to make research-grade hES cell lines

BioTime, Inc. today announced a material transfer agreement (MTA) with the University of California (UC) system to make five research-grade human embryonic stem (hES) cell lines available to UC system researchers. These lines are genetically identical to a bank of GMP-compliant hES cell lines that will be made available to California-based researchers under a recent agreement between BioTime and the California Institute for Regenerative Medicine (CIRM).

23 Dec 2010

Study provides evidence on prevalence of two separate mosquito species which carry malaria parasite

In notable back-to-back papers appearing in the prestigioous journal Science in October, teams of researchers, one led by Nora Besansky, a professor of biological sciences and a member of the Eck Institute for Global Health at the University of Notre Dame, provided evidence that Anopheles gambiae, which is one of the major mosquito carriers of the malaria parasite in Sub-Saharan Africa, is evolving into two separate species with different traits.

21 Dec 2010

DNA sequence variations linked with heart's electrical rhythm in several surprising regions

A study among almost 50,000 people worldwide has identified DNA sequence variations linked with the heart's electrical rhythm in several surprising regions among 22 locations across the human genome. The variants were found by an international consortium, including Johns Hopkins researchers, and reported Nov. 14 in the Nature Genetics advance online publication.

21 Dec 2010

DNA tunneling detector embedded in a ‘Nanopore’

Scientists from Imperial College London are developing technology that could ultimately sequence a person's genome in mere minutes, at a fraction of the cost of current commercial techniques.

20 Dec 2010

EpiTherapeutics, Abbott to develop new anti-cancer drugs

EpiTherapeutics and Abbott today announced a collaboration agreement to develop new anti-cancer drugs by making small-molecule inhibitors against selected epigenetic oncology targets.